JPH026326B2 - - Google Patents

Info

Publication number
JPH026326B2
JPH026326B2 JP8980682A JP8980682A JPH026326B2 JP H026326 B2 JPH026326 B2 JP H026326B2 JP 8980682 A JP8980682 A JP 8980682A JP 8980682 A JP8980682 A JP 8980682A JP H026326 B2 JPH026326 B2 JP H026326B2
Authority
JP
Japan
Prior art keywords
background background
animals
humans
infections
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP8980682A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58206517A (ja
Inventor
Masakazu Yamamoto
Seiichi Araki
Hiroshi Yamamoto
Isao Yamatsu
Takeshi Suzuki
Shoji Kajiwara
Yoshikazu Suzuki
Masae Arai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to JP57089806A priority Critical patent/JPS58206517A/ja
Priority to DE3348492A priority patent/DE3348492C2/de
Priority to DE3348500A priority patent/DE3348500C2/de
Priority to GB08314419A priority patent/GB2122610B/en
Priority to DE3348493A priority patent/DE3348493C2/de
Priority to DE3318989A priority patent/DE3318989C2/de
Priority to SE8303013A priority patent/SE461650B/sv
Priority to DK239483A priority patent/DK171640B1/da
Priority to CH2902/83A priority patent/CH654823A5/fr
Priority to NL8301892A priority patent/NL194300C/nl
Priority to ES522789A priority patent/ES8406992A1/es
Priority to BE2/60109A priority patent/BE896865A/fr
Priority to CA000429108A priority patent/CA1310660C/en
Priority to IT21364/83A priority patent/IT1164256B/it
Priority to AT0197283A priority patent/AT389871B/de
Priority to FR838308941A priority patent/FR2527597B1/fr
Priority to FR8317171A priority patent/FR2532844B1/fr
Priority to FR8317176A priority patent/FR2532847B1/fr
Priority to FR8317169A priority patent/FR2532843A1/fr
Priority to FR8317173A priority patent/FR2532845B1/fr
Priority to FR8317175A priority patent/FR2532846B1/fr
Priority to FR8317170A priority patent/FR2532848B1/fr
Publication of JPS58206517A publication Critical patent/JPS58206517A/ja
Priority to ES529753A priority patent/ES8506567A1/es
Priority to ES529754A priority patent/ES8507444A1/es
Priority to GB08508215A priority patent/GB2159709B/en
Priority to GB08508217A priority patent/GB2159710B/en
Priority to GB08508220A priority patent/GB2159713A/en
Priority to GB08508218A priority patent/GB2159711B/en
Priority to GB08508216A priority patent/GB2159055B/en
Priority to GB08508219A priority patent/GB2159712B/en
Priority to GB08508214A priority patent/GB2159054B/en
Priority to US06/760,221 priority patent/US4624966A/en
Priority to FR858513026A priority patent/FR2569108B1/fr
Priority to SE8801514A priority patent/SE502923C2/sv
Priority to SE8801513A priority patent/SE502922C2/sv
Priority to SE8801515A priority patent/SE502924C2/sv
Publication of JPH026326B2 publication Critical patent/JPH026326B2/ja
Priority to US08/011,197 priority patent/US5280048A/en
Priority to US08/584,145 priority patent/US6111131A/en
Priority to US08/601,489 priority patent/US6288128B1/en
Priority to US08/599,944 priority patent/US5658958A/en
Priority to NL9900009A priority patent/NL9900009A/nl
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/15—Unsaturated ethers containing only non-aromatic carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/203—Unsaturated compounds containing keto groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/14—Acetic acid esters of monohydroxylic compounds
    • C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP57089806A 1982-05-28 1982-05-28 免疫機能不全による疾患の予防・治療剤 Granted JPS58206517A (ja)

Priority Applications (41)

Application Number Priority Date Filing Date Title
JP57089806A JPS58206517A (ja) 1982-05-28 1982-05-28 免疫機能不全による疾患の予防・治療剤
DE3348492A DE3348492C2 (de) 1982-05-28 1983-05-25 Verwendung eines ß,gamma-Dihydropolyprenylalkoholderivats zur Prophylaxe und Therapie von durch Immunmangelerscheinungen verursachten Infektionskrankheiten
DE3348500A DE3348500C2 (de) 1982-05-28 1983-05-25 beta,gamma-Dihydropolyprenylalkoholderivat
GB08314419A GB2122610B (en) 1982-05-28 1983-05-25 A polyprenyl compound and a pharmaceutical composition containing a polyprenyl compound
DE3348493A DE3348493C2 (de) 1982-05-28 1983-05-25 Verwendung von Docosanol zur Behandlung und Prophylaxe von durch Immunmangelerscheinungen verursachten Infektionskrankheiten
DE3318989A DE3318989C2 (de) 1982-05-28 1983-05-25 ß,gamma-Dihydropolyprenylalkoholderivate und diese enthaltende Arzneimittel und deren Verwendung
SE8303013A SE461650B (sv) 1982-05-28 1983-05-27 B -dihydropolyprenylalkoholderivat och farmaceutisk komposition innehaallande detsamma
DK239483A DK171640B1 (da) 1982-05-28 1983-05-27 Analogifremgangsmåde til fremstilling af beta, gamma-dihydro-polyprenylalkoholderivater
CH2902/83A CH654823A5 (fr) 1982-05-28 1983-05-27 Derives de l'alcool beta, gamma-dihydropolyprenylique et compositions pharmaceutiques contenant un compose polyprenylique.
NL8301892A NL194300C (nl) 1982-05-28 1983-05-27 Farmaceutisch preparaat, dat een polyprenol als werkzaam bestanddeel bevat, alsmede voor toepassing daarin geschikte polyprenolen.
ES522789A ES8406992A1 (es) 1982-05-28 1983-05-27 Un derivado de un alcohol b,v-dihidropoliprenilico.
BE2/60109A BE896865A (fr) 1982-05-28 1983-05-27 Derives de l'alcool beta, alpha-dihydropolyprenylique et composition pharmaceutique contenant un compose de polyprenyle.
CA000429108A CA1310660C (en) 1982-05-28 1983-05-27 B, -dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
IT21364/83A IT1164256B (it) 1982-05-28 1983-05-30 Derivati di beta, alfa-diidropoliprenil alcool e composizione farmaceutica contenente un composto di poliprenile
AT0197283A AT389871B (de) 1982-05-28 1983-05-30 Verfahren zur herstellung von beta, gamma -dihydropolyprenylalkoholderivaten
FR838308941A FR2527597B1 (fr) 1982-05-28 1983-05-30 Derives d'alcool b,g-dihydropolyprenylique et composition pharmaceutique contenant un compose polyprenylique
FR8317170A FR2532848B1 (fr) 1982-05-28 1983-10-27 Composition pharmaceutique contenant un derive polyprenylique
FR8317176A FR2532847B1 (fr) 1982-05-28 1983-10-27 Composition pharmaceutique comprenant a titre de principe actif le 3,7,11,15-tetramethylhexadeca-1-ene-3-ol
FR8317169A FR2532843A1 (fr) 1982-05-28 1983-10-27 Composition pharmaceutique comprenant a titre de principe actif le phytol ou l'isophytol
FR8317173A FR2532845B1 (fr) 1982-05-28 1983-10-27 Composition pharmaceutique comprenant a titre de principe actif le docosanol
FR8317175A FR2532846B1 (fr) 1982-05-28 1983-10-27 Composition pharmaceutique comprenant a titre de principe actif le 3,7,11,15 - tetramethyl -1,6,10,14-hexadecatetraene-3-ol
FR8317171A FR2532844B1 (fr) 1982-05-28 1983-10-27 Composition pharmaceutique contenant un compose polyprenylique
ES529753A ES8506567A1 (es) 1982-05-28 1984-02-15 Un procedimiento para la preparacion de un derivado de un alcohol , -dihidropoliprenilico
ES529754A ES8507444A1 (es) 1982-05-28 1984-02-15 Un procedimiento para la preparacion de un derivado de un alcohol , -dihidropoliprenilico
GB08508214A GB2159054B (en) 1982-05-28 1985-03-29 Pharmaceutical compositions of polyprenyl alcohols
GB08508216A GB2159055B (en) 1982-05-28 1985-03-29 Pharmaceutical compositions of 3,7,11,15-tetra-methylhexadec-1-en-3-ol
GB08508217A GB2159710B (en) 1982-05-28 1985-03-29 Containing a polyprenyl compound
GB08508220A GB2159713A (en) 1982-05-28 1985-03-29 Containing a polyprenyl compound
GB08508218A GB2159711B (en) 1982-05-28 1985-03-29 Containing a polyprenyl compound
GB08508215A GB2159709B (en) 1982-05-28 1985-03-29 Containing a polyprenyl compound
GB08508219A GB2159712B (en) 1982-05-28 1985-03-29 Containing a polyprenyl compound
US06/760,221 US4624966A (en) 1982-05-28 1985-07-29 β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
FR858513026A FR2569108B1 (fr) 1982-05-28 1985-09-02 Composition pharmaceutique contenant un compose polyprenylique
SE8801515A SE502924C2 (sv) 1982-05-28 1988-04-22 Farmaceutisk komposition innehållande en verksam mängd av 3,7,11,15-tetrametyl-hexadeka-1-en-3-ol eller 3,7,11,15- tetrametyl-1,6,10,14-hexadekatetraen-3-ol
SE8801514A SE502923C2 (sv) 1982-05-28 1988-04-22 Användning av en polyprenylförening för framställning av protylaktiskt/terapeutiskt medel för humana och animala sjukdomar beroende på bristfälligt immunförsvar
SE8801513A SE502922C2 (sv) 1982-05-28 1988-04-22 Användning av en polyprenylförening för framställning av profylaktiskt/terapeutiskt medel för humana och animala sjukdomar beroende på bristfälligt immunförsvar
US08/011,197 US5280048A (en) 1982-05-28 1993-01-29 β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
US08/584,145 US6111131A (en) 1982-05-28 1996-01-11 Beta, gamma-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
US08/601,489 US6288128B1 (en) 1982-05-28 1996-02-14 β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
US08/599,944 US5658958A (en) 1982-05-28 1996-02-14 β, γ-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals
NL9900009A NL9900009A (nl) 1982-05-28 2000-12-05 Beta, gamma-dihydropolyprenylalcoholderivaten en farmaceutisch preparaat, dat een polyprenylverbinding bevat.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57089806A JPS58206517A (ja) 1982-05-28 1982-05-28 免疫機能不全による疾患の予防・治療剤

Publications (2)

Publication Number Publication Date
JPS58206517A JPS58206517A (ja) 1983-12-01
JPH026326B2 true JPH026326B2 (enrdf_load_stackoverflow) 1990-02-08

Family

ID=13980959

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57089806A Granted JPS58206517A (ja) 1982-05-28 1982-05-28 免疫機能不全による疾患の予防・治療剤

Country Status (2)

Country Link
JP (1) JPS58206517A (enrdf_load_stackoverflow)
BE (1) BE896865A (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5973533A (ja) * 1982-10-21 1984-04-25 Eisai Co Ltd β，γ−ジヒドロポリプレニルアルコ−ル誘導体

Also Published As

Publication number Publication date
BE896865A (fr) 1983-11-28
JPS58206517A (ja) 1983-12-01

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