JPH0223191B2 - - Google Patents

Info

Publication number
JPH0223191B2
JPH0223191B2 JP56500145A JP50014581A JPH0223191B2 JP H0223191 B2 JPH0223191 B2 JP H0223191B2 JP 56500145 A JP56500145 A JP 56500145A JP 50014581 A JP50014581 A JP 50014581A JP H0223191 B2 JPH0223191 B2 JP H0223191B2
Authority
JP
Japan
Prior art keywords
cells
culture
epithelium
tissue
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP56500145A
Other languages
English (en)
Japanese (ja)
Other versions
JPS56501601A (https=
Inventor
Hawaado Guriin
Oranii Kehinde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of JPS56501601A publication Critical patent/JPS56501601A/ja
Publication of JPH0223191B2 publication Critical patent/JPH0223191B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915—Method or apparatus for preparing biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP56500145A 1979-11-14 1980-11-12 Expired - Lifetime JPH0223191B2 (https=)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/094,003 US4304866A (en) 1979-11-14 1979-11-14 Transplantable sheets of living keratinous tissue

Publications (2)

Publication Number Publication Date
JPS56501601A JPS56501601A (https=) 1981-11-05
JPH0223191B2 true JPH0223191B2 (https=) 1990-05-23

Family

ID=22242181

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56500145A Expired - Lifetime JPH0223191B2 (https=) 1979-11-14 1980-11-12

Country Status (5)

Country Link
US (1) US4304866A (https=)
EP (1) EP0040240A1 (https=)
JP (1) JPH0223191B2 (https=)
CA (1) CA1159777A (https=)
WO (1) WO1981001416A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2230298A1 (en) 2003-02-06 2010-09-22 Cellseed Inc. Anterior ocular segment related cell sheets, three-dimensional structures, and processes for producing the same
EP2450065A1 (en) 2003-02-06 2012-05-09 Cellseed Inc. Corneal epithelium forming cell sheets, processes for producing the same, and methods of using the same

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458678A (en) * 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US4505266A (en) * 1981-10-26 1985-03-19 Massachusetts Institute Of Technology Method of using a fibrous lattice
US4520821A (en) * 1982-04-30 1985-06-04 The Regents Of The University Of California Growing of long-term biological tissue correction structures in vivo
DE3247387C2 (de) * 1982-12-22 1984-11-22 Rolf Prof. Dr.med. 7400 Tübingen Hettich Verfahren zur Herstellung eines Transplantats und Vorrichtung zur Durchführung des Verfahrens
US4769317A (en) * 1983-06-14 1988-09-06 Hefton John M Process for growing human epidermis, product thereof
US5000963A (en) * 1983-06-14 1991-03-19 Hefton John M Method of treating the skin using human epidermal sheets
US4609551A (en) * 1984-03-20 1986-09-02 Arnold Caplan Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites
IL79289A (en) * 1985-07-05 1992-01-15 Whitehead Biomedical Inst Introduction and expression of foreign genetic material into keratinocytes using a recombinant retrovirus
FR2585567B1 (fr) * 1985-08-01 1988-09-16 Seguin Marie Christine Nouvelle composition cosmetique issue de cultures cellulaires de tissu conjonctif
FR2589165B1 (fr) * 1985-10-24 1989-01-20 Inst Nat Sante Rech Med Procede d'obtention d'un epithelium humain de culture, tissu epithelial obtenu et son application aux allogreffes
US4918002A (en) * 1986-08-21 1990-04-17 President And Fellows Of Harvard College Keratinocyte megacolonies, and assays for growth factors
US6309635B1 (en) 1986-11-20 2001-10-30 Children's Medical Center Corp. Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo
CA1340581C (en) * 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
US5804178A (en) * 1986-11-20 1998-09-08 Massachusetts Institute Of Technology Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue
US5567612A (en) * 1986-11-20 1996-10-22 Massachusetts Institute Of Technology Genitourinary cell-matrix structure for implantation into a human and a method of making
US4888291A (en) * 1987-06-19 1989-12-19 President And Fellows Of Harvard College Human epithelium originating from cell cultures
IT1207525B (it) * 1987-06-23 1989-05-25 Ist Naz Ric Sul Cancro Metodo per la preservazione difogli trapiantabili di epitelio coltivato in vitro vitale.
EP0430996A4 (en) * 1988-08-04 1991-11-13 President And Fellows Of Harvard College Transplantig cultured epithelial cells with a desired phenotypic trait
US5817075A (en) * 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US6514238B1 (en) * 1989-08-14 2003-02-04 Photogenesis, Inc. Method for preparation and transplantation of volute grafts and surgical instrument therefor
SG49267A1 (en) * 1989-08-14 1998-05-18 Photogenesis Inc Surgical instrument and cell isolation and transplantation
US5423778A (en) * 1989-12-14 1995-06-13 Elof Eriksson System and method for transplantation of cells
US5661132A (en) * 1989-12-14 1997-08-26 Auragen, Inc. Wound healing
US5697901A (en) * 1989-12-14 1997-12-16 Elof Eriksson Gene delivery by microneedle injection
US6090790A (en) 1989-12-14 2000-07-18 Eriksson; Elof Gene delivery by microneedle injection
US5292655A (en) * 1990-01-29 1994-03-08 Wille Jr John J Method for the formation of a histologically-complete skin substitute
US5834312A (en) * 1990-01-29 1998-11-10 Hy-Gene, Inc. Process and media for the growth of human epithelia
US5100676A (en) * 1990-02-02 1992-03-31 Biosurface Technology, Inc. Cool storage of cultured epithelial sheets
RU2135191C1 (ru) * 1990-04-24 1999-08-27 Ортек Интернэшнл, Инк. Композиционный эквивалент живой кожи, способ его получения, тест-набор
US5040677A (en) * 1990-06-04 1991-08-20 Biosurface Technology, Inc. Container for storage and distribution of a skin wound dressing
US8067149B2 (en) * 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
US6120991A (en) * 1990-10-30 2000-09-19 Fred Hutchinson Cancer Research Center Epiligrin, an epithelial ligand for integrins
US5830678A (en) * 1990-10-30 1998-11-03 Fred Hutchinson Cancer Research Center Method for identifying a target peptide that modulates the binding of epinectin ligand to integrin receptors
WO1993007913A1 (en) * 1991-10-24 1993-04-29 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
WO1993008776A1 (en) * 1991-11-01 1993-05-13 Culture Technology, Inc. Cultured skin graft carrier
US6585969B1 (en) 1991-11-20 2003-07-01 N. V. Innogenetics S.A. Non-viable keratinocyte cell composition or lysate for promoting wound healing
ES2149779T3 (es) * 1991-11-20 2000-11-16 Innogenetics Nv Lisados derivados de queratinocitos para utilizacion como substancias cicatrizantes.
US6045791A (en) * 1992-03-06 2000-04-04 Photogenesis, Inc. Retinal pigment epithelium transplantation
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5411872A (en) * 1993-09-08 1995-05-02 Cornell Research Foundation, Inc. Method for transfected cell selection
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5618718A (en) * 1994-12-30 1997-04-08 Universite Laval Production of a contractile smooth muscle
US5868728A (en) * 1995-02-28 1999-02-09 Photogenesis, Inc. Medical linear actuator for surgical delivery, manipulation, and extraction
US6123727A (en) 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US7422574B2 (en) * 1995-05-19 2008-09-09 Applied Tissue Technologies, Llc Microseeding device for gene delivery by microneedle injection
US5741685A (en) * 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
US6129761A (en) * 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US6692961B1 (en) * 1996-10-11 2004-02-17 Invitrogen Corporation Defined systems for epithelial cell culture and use thereof
US6378527B1 (en) 1998-04-08 2002-04-30 Chondros, Inc. Cell-culture and polymer constructs
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
DE19958693C2 (de) * 1999-12-06 2002-07-18 Biotissue Technologies Gmbh Verfahren und Zusammensetzungen zur Herstellung von Zelltransplantaten
DE60143892D1 (de) * 2000-07-21 2011-03-03 Cellseed Ind Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung
US8889417B2 (en) 2000-07-21 2014-11-18 Cellseed Inc. Epidermal cultured cell sheet, multi-layered cultured skin sheet and processes for producing those sheets
AUPR298901A0 (en) * 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
US7262174B2 (en) * 2001-05-09 2007-08-28 Geron Corporation Treatment for wounds
FR2825370A1 (fr) * 2001-05-31 2002-12-06 Inst Nat Sante Rech Med Keratinocytes obtenus a partir de cellules souches embryonnaires de mammiferes
US7189245B2 (en) * 2002-02-14 2007-03-13 Photogenesis, Inc. Subretinal implantation device and surgical cannulas for use therewith
JP4338493B2 (ja) * 2003-10-10 2009-10-07 株式会社 ジャパン・ティッシュ・エンジニアリング 細胞培養体の生産方法
WO2014009276A1 (en) * 2012-07-09 2014-01-16 Roche Diagnostics Gmbh Recombinantly produced neutral protease originating from paenibacillus polymyxa
AU2013205148B2 (en) 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom
DE202023002794U1 (de) 2022-12-27 2024-07-15 AVITA Medical Americas, LLC Kassette zur Herstellung einer regenerativen epidermalen Suspension
US12570949B2 (en) 2022-12-27 2026-03-10 AVITA Medical Americas, LLC Systems and devices for wound therapy and related methods of use
USD1112812S1 (en) 2023-12-22 2026-02-10 AVITA Medical Americas, LLC Tissue processing cartridge

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5651747B2 (https=) * 1973-05-31 1981-12-08
US4016036A (en) * 1975-11-14 1977-04-05 Massachusetts Institute Of Technology Process for serially culturing keratinocytes

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2230298A1 (en) 2003-02-06 2010-09-22 Cellseed Inc. Anterior ocular segment related cell sheets, three-dimensional structures, and processes for producing the same
EP2267115A1 (en) 2003-02-06 2010-12-29 Cellseed Inc. Anterior ocular segment related cell sheets, three-dimensional structures, and processes for producing the same
EP2450065A1 (en) 2003-02-06 2012-05-09 Cellseed Inc. Corneal epithelium forming cell sheets, processes for producing the same, and methods of using the same

Also Published As

Publication number Publication date
WO1981001416A1 (en) 1981-05-28
JPS56501601A (https=) 1981-11-05
US4304866A (en) 1981-12-08
EP0040240A1 (en) 1981-11-25
CA1159777A (en) 1984-01-03

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