JPH0120153B2 - - Google Patents

Info

Publication number
JPH0120153B2
JPH0120153B2 JP55080482A JP8048280A JPH0120153B2 JP H0120153 B2 JPH0120153 B2 JP H0120153B2 JP 55080482 A JP55080482 A JP 55080482A JP 8048280 A JP8048280 A JP 8048280A JP H0120153 B2 JPH0120153 B2 JP H0120153B2
Authority
JP
Japan
Prior art keywords
chloroform
acetone
culture
methanol
silica gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55080482A
Other languages
English (en)
Japanese (ja)
Other versions
JPS577479A (en
Inventor
Fusao Tomita
Tatsuya Tamaoki
Kimikatsu Shirahata
Masaji Kasai
Noriaki Hirayama
Makoto Morimoto
Masanori Fukui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP8048280A priority Critical patent/JPS577479A/ja
Priority to US06/252,062 priority patent/US4346075A/en
Priority to EP81104619A priority patent/EP0042172B1/en
Priority to DE8181104619T priority patent/DE3167053D1/de
Priority to US06/273,377 priority patent/US4393056A/en
Publication of JPS577479A publication Critical patent/JPS577479A/ja
Publication of JPH0120153B2 publication Critical patent/JPH0120153B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora
    • C12R2001/30—Micromonospora chalcea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
JP8048280A 1980-06-14 1980-06-14 Tetronolide compound Granted JPS577479A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP8048280A JPS577479A (en) 1980-06-14 1980-06-14 Tetronolide compound
US06/252,062 US4346075A (en) 1980-06-14 1981-04-08 Antibiotic DC-11 and process for production thereof
EP81104619A EP0042172B1 (en) 1980-06-14 1981-06-15 Antibiotic compounds, pharmaceutical compositions containing such compounds, process for production thereof
DE8181104619T DE3167053D1 (en) 1980-06-14 1981-06-15 Antibiotic compounds, pharmaceutical compositions containing such compounds, process for production thereof
US06/273,377 US4393056A (en) 1980-06-14 1981-06-15 Antibiotics tetronolide compounds and process for production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8048280A JPS577479A (en) 1980-06-14 1980-06-14 Tetronolide compound

Publications (2)

Publication Number Publication Date
JPS577479A JPS577479A (en) 1982-01-14
JPH0120153B2 true JPH0120153B2 (en, 2012) 1989-04-14

Family

ID=13719489

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8048280A Granted JPS577479A (en) 1980-06-14 1980-06-14 Tetronolide compound

Country Status (4)

Country Link
US (1) US4393056A (en, 2012)
EP (1) EP0042172B1 (en, 2012)
JP (1) JPS577479A (en, 2012)
DE (1) DE3167053D1 (en, 2012)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5661398A (en) * 1979-10-26 1981-05-26 Kyowa Hakko Kogyo Co Ltd Substance dc-45 and its preparation
CA2342325A1 (en) * 1998-08-31 2000-03-09 Kyowa Hakko Kogyo Co., Ltd. An agent for inducing apoptosis
CN111170975B (zh) * 2020-01-19 2021-11-23 中国科学院南海海洋研究所 抗生素lobophorin及其制备方法和应用
CN114180599B (zh) * 2021-12-23 2023-04-14 江苏兄弟维生素有限公司 从硝酸硫胺母液中回收硝酸铵的工艺及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3144466A (en) * 1963-03-08 1964-08-11 Pfizer & Co C Diacyl esters of de-oleandrosehydroxyoleandomycin and process therefor
DE2329012A1 (de) * 1972-06-12 1973-12-20 Scherico Ltd Aminoglykosidantibiotika und ihre herstellung aus micromonospora
US4161523A (en) * 1972-11-15 1979-07-17 Schering Corporation Rosamicin esters, acid addition salts and methods for production thereof
JPS54138501A (en) * 1978-04-20 1979-10-27 Kyowa Hakko Kogyo Co Ltd Antibiotic dc-11 and preparation thereof
US4346075A (en) * 1980-06-14 1982-08-24 Kyowa Hakko Kogyo Co., Ltd. Antibiotic DC-11 and process for production thereof

Also Published As

Publication number Publication date
JPS577479A (en) 1982-01-14
EP0042172A1 (en) 1981-12-23
US4393056A (en) 1983-07-12
EP0042172B1 (en) 1984-11-07
DE3167053D1 (en) 1984-12-13

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