JP7842776B2 - インドシアニングリーンの安定な処方物 - Google Patents

インドシアニングリーンの安定な処方物

Info

Publication number
JP7842776B2
JP7842776B2 JP2023557322A JP2023557322A JP7842776B2 JP 7842776 B2 JP7842776 B2 JP 7842776B2 JP 2023557322 A JP2023557322 A JP 2023557322A JP 2023557322 A JP2023557322 A JP 2023557322A JP 7842776 B2 JP7842776 B2 JP 7842776B2
Authority
JP
Japan
Prior art keywords
indocyanine green
composition
edta
composition according
icg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2023557322A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024510302A5 (enExample
JP2024510302A (ja
Inventor
ローラン・マリナ
サヤ・ババ
ロペ・ニコラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Provepharm Life Solutions SA
Original Assignee
Provepharm Life Solutions SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Provepharm Life Solutions SA filed Critical Provepharm Life Solutions SA
Publication of JP2024510302A publication Critical patent/JP2024510302A/ja
Publication of JP2024510302A5 publication Critical patent/JP2024510302A5/ja
Application granted granted Critical
Publication of JP7842776B2 publication Critical patent/JP7842776B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2023557322A 2021-03-17 2022-03-14 インドシアニングリーンの安定な処方物 Active JP7842776B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21305323.4 2021-03-17
EP21305323 2021-03-17
PCT/EP2022/056445 WO2022194733A2 (en) 2021-03-17 2022-03-14 Stable formulations of indocyanine green

Publications (3)

Publication Number Publication Date
JP2024510302A JP2024510302A (ja) 2024-03-06
JP2024510302A5 JP2024510302A5 (enExample) 2025-02-06
JP7842776B2 true JP7842776B2 (ja) 2026-04-08

Family

ID=75302475

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023557322A Active JP7842776B2 (ja) 2021-03-17 2022-03-14 インドシアニングリーンの安定な処方物

Country Status (6)

Country Link
US (1) US20240165275A1 (enExample)
EP (1) EP4308081A2 (enExample)
JP (1) JP7842776B2 (enExample)
CN (1) CN116997325B (enExample)
BR (1) BR112023018942A2 (enExample)
WO (1) WO2022194733A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119215199B (zh) * 2024-10-12 2025-12-09 石家庄四药有限公司 一种注射用吲哚菁绿的冻干工艺

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002508760A (ja) 1997-06-16 2002-03-19 ニユコメド・イメージング・アクシエセルカペト 光音響画像形成方法
JP2009100702A (ja) 2007-10-25 2009-05-14 Chiba Univ 胚性幹細胞から肝芽細胞を得る方法
JP2015040185A (ja) 2013-08-21 2015-03-02 キヤノン株式会社 造影用組成物
JP2018524278A (ja) 2015-05-11 2018-08-30 イーティーエイチ・チューリッヒ 循環系視覚化のための組成物
WO2020240514A1 (en) 2019-05-30 2020-12-03 Leiutis Pharmaceuticals Pvt, Ltd. Stable formulations of indocyanine green

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08509260A (ja) * 1993-04-20 1996-10-01 マリンクロット・メディカル・インコーポレイテッド 電圧感受性染料の安定化
FR2710060B1 (fr) 1993-09-17 1995-11-17 Rech Biolog Et Procédé de préparation de benz[e]indoles substitués de pureté élevée et leurs sels alcalins.
US6944493B2 (en) 1999-09-10 2005-09-13 Akora, Inc. Indocyanine green (ICG) compositions and related methods of use
US8337809B2 (en) * 2006-09-11 2012-12-25 William Marsh Rice University Charge-assembled capsules for phototherapy
DE102007030403A1 (de) 2007-06-29 2009-01-08 Universität Bielefeld Verfahren zur Verbesserung der Photostabilität von Fluoreszenzfarbstoffen
CN103301482B (zh) 2013-06-27 2014-12-17 深圳先进技术研究院 两亲性三嵌段聚多肽载icg胶束及其制备方法
JP6623479B2 (ja) 2015-02-08 2019-12-25 トンリ・バイオメディカル・カンパニー・リミテッド 脂質ナノ粒子及びその使用
DK3383436T3 (da) 2015-12-01 2023-11-20 Dishman Carbogen Amcis Ltd Forbedret fremgangsmåde til fremstilling af indocyaningrønt
US20190337896A1 (en) 2018-05-02 2019-11-07 Biophore India Pharmaceuticals Pvt. Ltd. PROCESS FOR THE PREPARATION OF SODIUM 4-(2-((1E,3E,5E,7Z)-7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO[e]INDOL-2(3H)-YLIDENE) HEPTA-1,3,5-TRIENYL)-1,1-DIMETHYL-1H-BENZO[e]INDOLIUM-3-YL) BUTANE-1-SULFONATE (INDOCYANINE GREEN)
CN111514125B (zh) * 2020-05-26 2021-03-23 中山万汉制药有限公司 含有喹诺酮类化合物与依地酸类化合物的组合物

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002508760A (ja) 1997-06-16 2002-03-19 ニユコメド・イメージング・アクシエセルカペト 光音響画像形成方法
JP2009100702A (ja) 2007-10-25 2009-05-14 Chiba Univ 胚性幹細胞から肝芽細胞を得る方法
JP2015040185A (ja) 2013-08-21 2015-03-02 キヤノン株式会社 造影用組成物
JP2018524278A (ja) 2015-05-11 2018-08-30 イーティーエイチ・チューリッヒ 循環系視覚化のための組成物
WO2020240514A1 (en) 2019-05-30 2020-12-03 Leiutis Pharmaceuticals Pvt, Ltd. Stable formulations of indocyanine green

Also Published As

Publication number Publication date
CN116997325A (zh) 2023-11-03
EP4308081A2 (en) 2024-01-24
US20240165275A1 (en) 2024-05-23
WO2022194733A2 (en) 2022-09-22
BR112023018942A2 (pt) 2023-10-10
WO2022194733A3 (en) 2022-11-10
JP2024510302A (ja) 2024-03-06
CN116997325B (zh) 2025-12-05

Similar Documents

Publication Publication Date Title
US20240091198A1 (en) Aqueous composition comprising dantrolene
CN103826612B (zh) 一种新的包含阿朴吗啡作为活性成分的治疗组合物
JP2018531268A6 (ja) ダントロレンを含む水性組成物
US20200188478A1 (en) Pre-mixed, ready to use vancomycin compositions
WO2008023807A1 (fr) Composition pharmaceutique stabilisée
US20210059967A1 (en) Liquid parenteral compositions of levothyroxine
JP7400180B2 (ja) 非経口製剤及びその使用
JP2025011312A (ja) p-ボロノフェニルアラニンを含有する注射液剤の析出防止方法
CN116997325B (zh) 稳定的吲哚菁绿制剂
JP2024500187A (ja) 非経口カンナビノイド配合物およびその使用
EP4308076B1 (en) Stable formulations of indocyanine green
JP2019502751A5 (enExample)
WO2026066169A1 (zh) 维生素d3注射液药物组合物及其用途
CN117062597B (zh) 稳定的吲哚菁绿制剂
EP1293206A1 (en) Water-based liquid preparation
MXPA94002884A (es) Composicion acuosa estable durante el almacenamiento y metodo para hacer la misma.
JP3668225B2 (ja) Oct製剤
CA2486571C (en) Pharmaceutical composition
CN116367822A (zh) 植物甲萘醌组合物
TW202114717A (zh) 含有對硼苯基丙胺酸之注射液劑
US20210251889A1 (en) N-Acetylcysteine Compositions and Methods
WO2026008654A1 (en) Liquid pharmaceutical composition of tretinoin

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250129

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20250129

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20251205

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20251209

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20251212

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20260303

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20260327

R150 Certificate of patent or registration of utility model

Ref document number: 7842776

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150