JP7809729B2 - ニコチンアミドアデニンジヌクレオチドの安定化方法及び安定化用組成物 - Google Patents
ニコチンアミドアデニンジヌクレオチドの安定化方法及び安定化用組成物Info
- Publication number
- JP7809729B2 JP7809729B2 JP2023577019A JP2023577019A JP7809729B2 JP 7809729 B2 JP7809729 B2 JP 7809729B2 JP 2023577019 A JP2023577019 A JP 2023577019A JP 2023577019 A JP2023577019 A JP 2023577019A JP 7809729 B2 JP7809729 B2 JP 7809729B2
- Authority
- JP
- Japan
- Prior art keywords
- nad
- nicotinamide
- sample
- composition
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90209—Oxidoreductases (1.) acting on NADH or NADPH (1.6), e.g. those with a heme protein as acceptor (1.6.2) (general), Cytochrome-b5 reductase (1.6.2.2) or NADPH-cytochrome P450 reductase (1.6.2.4)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022011518 | 2022-01-28 | ||
| JP2022011518 | 2022-01-28 | ||
| PCT/JP2023/002617 WO2023145872A1 (ja) | 2022-01-28 | 2023-01-27 | ニコチンアミドアデニンジヌクレオチドの安定化方法及び安定化用組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2023145872A1 JPWO2023145872A1 (https=) | 2023-08-03 |
| JPWO2023145872A5 JPWO2023145872A5 (https=) | 2024-10-04 |
| JP7809729B2 true JP7809729B2 (ja) | 2026-02-02 |
Family
ID=87471637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023577019A Active JP7809729B2 (ja) | 2022-01-28 | 2023-01-27 | ニコチンアミドアデニンジヌクレオチドの安定化方法及び安定化用組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250101486A1 (https=) |
| EP (1) | EP4471153A4 (https=) |
| JP (1) | JP7809729B2 (https=) |
| CN (1) | CN118591635A (https=) |
| WO (1) | WO2023145872A1 (https=) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000007696A (ja) | 1998-06-25 | 2000-01-11 | Iatron Lab Inc | 還元型ニコチンアミドアデニンジヌクレオチド類の分解を防止する方法及び分解防止用試薬 |
| JP2003057235A (ja) | 2001-08-10 | 2003-02-26 | Internatl Reagents Corp | 物質の安定化方法 |
| JP2020033288A (ja) | 2018-08-29 | 2020-03-05 | 株式会社シノテスト | Ｎａｄｈ及びｎａｄｐｈの安定化方法 |
| JP2020048473A (ja) | 2018-09-26 | 2020-04-02 | 株式会社シノテスト | Ｎａｄｈ及びｎａｄｐｈの安定化法 |
| WO2021192683A1 (ja) | 2020-03-27 | 2021-09-30 | オリエンタル酵母工業株式会社 | β－ニコチンアミドモノヌクレオチド又はその薬理学的に許容される塩からなる化合物、並びにその品質評価方法および酵素反応性の判定方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53107486A (en) * | 1977-02-28 | 1978-09-19 | Wako Pure Chem Ind Ltd | Stabilized nadh aqueous solution |
| DE2814154A1 (de) * | 1978-04-01 | 1979-10-11 | Behringwerke Ag | Stabilisierte nicotinamid-nucleotide und verfahren zu ihrer herstellung |
| WO2017155100A1 (en) | 2016-03-11 | 2017-09-14 | Okinawa Institute Of Science And Technology School Corporation | A method, an apparatus, a system and a kit for determining the extent of aging |
| CN111269957A (zh) * | 2020-02-17 | 2020-06-12 | 宁波荷仁健康科技有限公司 | 一种基于比色法检测生物样品中nad+含量的方法及其应用 |
| JP7493761B2 (ja) | 2020-06-30 | 2024-06-03 | 株式会社川本製作所 | 多段ポンプ |
-
2023
- 2023-01-27 EP EP23747082.8A patent/EP4471153A4/en active Pending
- 2023-01-27 US US18/833,652 patent/US20250101486A1/en active Pending
- 2023-01-27 JP JP2023577019A patent/JP7809729B2/ja active Active
- 2023-01-27 WO PCT/JP2023/002617 patent/WO2023145872A1/ja not_active Ceased
- 2023-01-27 CN CN202380018381.3A patent/CN118591635A/zh active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000007696A (ja) | 1998-06-25 | 2000-01-11 | Iatron Lab Inc | 還元型ニコチンアミドアデニンジヌクレオチド類の分解を防止する方法及び分解防止用試薬 |
| JP2003057235A (ja) | 2001-08-10 | 2003-02-26 | Internatl Reagents Corp | 物質の安定化方法 |
| JP2020033288A (ja) | 2018-08-29 | 2020-03-05 | 株式会社シノテスト | Ｎａｄｈ及びｎａｄｐｈの安定化方法 |
| JP2020048473A (ja) | 2018-09-26 | 2020-04-02 | 株式会社シノテスト | Ｎａｄｈ及びｎａｄｐｈの安定化法 |
| WO2021192683A1 (ja) | 2020-03-27 | 2021-09-30 | オリエンタル酵母工業株式会社 | β－ニコチンアミドモノヌクレオチド又はその薬理学的に許容される塩からなる化合物、並びにその品質評価方法および酵素反応性の判定方法 |
Non-Patent Citations (1)
| Title |
|---|
| YOSHINO J. et al., Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiolog，Cell metabolism，2011年10月05日，vol. 14, no. 4，pp. 528-536 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023145872A1 (ja) | 2023-08-03 |
| JPWO2023145872A1 (https=) | 2023-08-03 |
| EP4471153A1 (en) | 2024-12-04 |
| US20250101486A1 (en) | 2025-03-27 |
| EP4471153A4 (en) | 2026-02-18 |
| CN118591635A (zh) | 2024-09-03 |
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