JP7808084B2 - （－）－アンブロックスを精製するための方法 - Google Patents

（－）－アンブロックスを精製するための方法

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Publication number
JP7808084B2
JP7808084B2 JP2023505874A JP2023505874A JP7808084B2 JP 7808084 B2 JP7808084 B2 JP 7808084B2 JP 2023505874 A JP2023505874 A JP 2023505874A JP 2023505874 A JP2023505874 A JP 2023505874A JP 7808084 B2 JP7808084 B2 JP 7808084B2
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Prior art keywords
ambrox
equal
crude
aqueous
washing
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Japanese (ja)
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JP2023536825A (ja
JP2023536825A5 (https=
Inventor
バラス，ジャン－ピエール
モレル，シルヴィー
アイクホルン，エリック
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ジボダン エス エー
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    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0069—Heterocyclic compounds
    • C11B9/0073—Heterocyclic compounds containing only O or S as heteroatoms
    • C11B9/0076—Heterocyclic compounds containing only O or S as heteroatoms the hetero rings containing less than six atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017—Squalene--hopene cyclase (5.4.99.17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
JP2023505874A 2020-07-30 2021-07-29 （－）－アンブロックスを精製するための方法 Active JP7808084B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2011823.8 2020-07-30
GBGB2011823.8A GB202011823D0 (en) 2020-07-30 2020-07-30 Method
PCT/EP2021/071246 WO2022023464A1 (en) 2020-07-30 2021-07-29 Method for purifying (-)-ambrox

Publications (3)

Publication Number Publication Date
JP2023536825A JP2023536825A (ja) 2023-08-30
JP2023536825A5 JP2023536825A5 (https=) 2024-07-18
JP7808084B2 true JP7808084B2 (ja) 2026-01-28

Family

ID=72425216

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023505874A Active JP7808084B2 (ja) 2020-07-30 2021-07-29 （－）－アンブロックスを精製するための方法

Country Status (8)

Country Link
US (2) US12404531B2 (https=)
EP (1) EP4188916A1 (https=)
JP (1) JP7808084B2 (https=)
CN (1) CN115803324A (https=)
BR (1) BR112023001441A2 (https=)
GB (1) GB202011823D0 (https=)
MX (1) MX2022014988A (https=)
WO (1) WO2022023464A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119137269A (zh) 2022-03-17 2024-12-13 奇华顿股份有限公司 Shc酶和酶变体
GB202313239D0 (en) * 2023-08-31 2023-10-18 Givaudan Sa Organic compounds

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010189285A (ja) 2009-02-16 2010-09-02 Kao Corp （±）−３ａ，６，６，９ａ−テトラメチルドデカヒドロナフト［２，１−ｂ］フラン類の製造方法
JP2013136625A (ja) 2003-02-20 2013-07-11 Eisai R & D Management Co Ltd Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法
JP2013224413A (ja) 2012-03-23 2013-10-31 Daxin Material Corp 硬質脆性材料の工作物を切削又は研削工具で切断する際に使用するための加工組成物
JP2014502956A (ja) 2010-10-19 2014-02-06 フューチャーフューエル ケミカル カンパニー 酢酸洗浄を用いた低硫酸エステル濃度の、５−スルホイソフタル酸モノリチウム塩の調製
WO2017017994A1 (ja) 2015-07-27 2017-02-02 栗田工業株式会社 逆浸透膜用洗浄剤、洗浄液、および洗浄方法
JP2018513198A (ja) 2015-04-24 2018-05-24 ジボダン エス エー アンブロクスを単離および精製するためのプロセス
JP2018513691A (ja) 2015-04-24 2018-05-31 ジボダン エス エー 酵素およびその適用
JP2020508651A (ja) 2017-02-24 2020-03-26 インターナショナル フレーバーズ アンド フラグランシズ インコーポレイテッド スクアレンホペンシクラーゼ、およびアンブロキサンを生成するためのその使用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58117294A (ja) * 1981-12-30 1983-07-12 ライオン株式会社 芳香性洗剤組成物
JPS60239481A (ja) 1984-05-14 1985-11-28 T Hasegawa Co Ltd （±）−アンブロツクスの製法及びその利用
DE3912318A1 (de) 1989-04-14 1990-10-18 Henkel Kgaa Verfahren zur stereoselektiven herstellung von 8(alpha),12-oxido-13,14,15,16-tetranorlabdan
US4970163A (en) 1989-08-28 1990-11-13 International Flavors & Fragrances Inc. Process for producing diol and lactone and microorganisms capable of same
US5290955A (en) 1991-12-29 1994-03-01 Kuraray Co., Ltd. Process for producing L-ambrox
DE4341275A1 (de) 1993-12-03 1995-06-08 Henkel Kgaa Verfahren zur Herstellung von 8alpha,12-Oxido-13,14,15,16-tetranorlabdan
JP5137834B2 (ja) * 2006-07-20 2013-02-06 旭化成ファーマ株式会社 置換フェニルアルカン酸の新規結晶及び製造方法
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product
JP7263244B2 (ja) 2017-02-24 2023-04-24 ビーエーエスエフ ソシエタス・ヨーロピア （３Ｅ，７Ｅ）－ホモファルネセン酸（ｈｏｍｏｆａｒｎｅｓｉｃ ａｃｉｄ）、または、（３Ｅ，７Ｅ）－ホモファルネセン酸エステルの製造のための方法

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013136625A (ja) 2003-02-20 2013-07-11 Eisai R & D Management Co Ltd Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法
JP2010189285A (ja) 2009-02-16 2010-09-02 Kao Corp （±）−３ａ，６，６，９ａ−テトラメチルドデカヒドロナフト［２，１−ｂ］フラン類の製造方法
JP2014502956A (ja) 2010-10-19 2014-02-06 フューチャーフューエル ケミカル カンパニー 酢酸洗浄を用いた低硫酸エステル濃度の、５−スルホイソフタル酸モノリチウム塩の調製
JP2013224413A (ja) 2012-03-23 2013-10-31 Daxin Material Corp 硬質脆性材料の工作物を切削又は研削工具で切断する際に使用するための加工組成物
JP2018513198A (ja) 2015-04-24 2018-05-24 ジボダン エス エー アンブロクスを単離および精製するためのプロセス
JP2018513691A (ja) 2015-04-24 2018-05-31 ジボダン エス エー 酵素およびその適用
WO2017017994A1 (ja) 2015-07-27 2017-02-02 栗田工業株式会社 逆浸透膜用洗浄剤、洗浄液、および洗浄方法
JP2020508651A (ja) 2017-02-24 2020-03-26 インターナショナル フレーバーズ アンド フラグランシズ インコーポレイテッド スクアレンホペンシクラーゼ、およびアンブロキサンを生成するためのその使用

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Adv. Synth. Catal.，2018年，Vol. 360，pp. 2339-2351
Agric. Biol. Chem.，1986年，Vol. 50, No. 6，pp. 1475-1480
Chemistry Letters，1999年，pp. 51-52
化学と生物，1967年，Vol. 5, No. 1，pp. 37-44
栄養と食糧，1978年，Vol. 31, No. 4，pp. 389-394
粉体技術，2009年，Vol. 1, No. 2，pp. 62-63

Also Published As

Publication number Publication date
MX2022014988A (es) 2023-01-04
US12404531B2 (en) 2025-09-02
CN115803324A (zh) 2023-03-14
JP2023536825A (ja) 2023-08-30
BR112023001441A2 (pt) 2023-02-14
US20260062725A1 (en) 2026-03-05
GB202011823D0 (en) 2020-09-16
EP4188916A1 (en) 2023-06-07
US20230212624A1 (en) 2023-07-06
WO2022023464A1 (en) 2022-02-03

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