JP7785452B2 - 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素 - Google Patents

免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素

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JP7785452B2
JP7785452B2 JP2020543733A JP2020543733A JP7785452B2 JP 7785452 B2 JP7785452 B2 JP 7785452B2 JP 2020543733 A JP2020543733 A JP 2020543733A JP 2020543733 A JP2020543733 A JP 2020543733A JP 7785452 B2 JP7785452 B2 JP 7785452B2
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cells
tgfbr2
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engineered
rna
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JP2021502113A (ja
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スティーブン マイケル バーリー
メリッサ チン
フレッド ハービンスキー
クリストファー ヒース ナイ
ブライズ ディー． サザー
クウィーニー ボン
ゴードン グラント ウェルステッド
クリス ウィルソン
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エディタス・メディシン，インコーポレイテッド
ジュノー セラピューティクス インコーポレイテッド
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12N2310/00—Structure or type of the nucleic acid
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JP2020543733A 2017-11-01 2018-11-01 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素 Active JP7785452B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023146660A JP2023179469A (ja) 2017-11-01 2023-09-11 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素
JP2025129240A JP2025156493A (ja) 2017-11-01 2025-08-01 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素

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US201762580320P 2017-11-01 2017-11-01
US62/580,320 2017-11-01
PCT/US2018/058635 WO2019089884A2 (en) 2017-11-01 2018-11-01 Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy

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JP2023146660A Division JP2023179469A (ja) 2017-11-01 2023-09-11 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素

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JP2021502113A5 JP2021502113A5 (https=) 2021-12-09
JP7785452B2 true JP7785452B2 (ja) 2025-12-15

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JP2023146660A Pending JP2023179469A (ja) 2017-11-01 2023-09-11 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素
JP2025129240A Pending JP2025156493A (ja) 2017-11-01 2025-08-01 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素

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JP2025129240A Pending JP2025156493A (ja) 2017-11-01 2025-08-01 免疫療法のためのｔ細胞におけるｔｇｆｂｒ２のｃｒｉｓｐｒ－ｃａｓ９編集のための方法、組成物、および構成要素

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US (1) US20230061455A1 (https=)
EP (1) EP3704251A2 (https=)
JP (3) JP7785452B2 (https=)
CN (1) CN111527209B (https=)
AU (2) AU2018358250B2 (https=)
BR (1) BR112020008478A2 (https=)
CA (1) CA3081456A1 (https=)
IL (1) IL274299B1 (https=)
MA (1) MA50858A (https=)
MX (2) MX2020004608A (https=)
SG (1) SG11202003862PA (https=)
WO (1) WO2019089884A2 (https=)

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