JP7778468B2 - Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断 - Google Patents

Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断

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JP7778468B2
JP7778468B2 JP2019547605A JP2019547605A JP7778468B2 JP 7778468 B2 JP7778468 B2 JP 7778468B2 JP 2019547605 A JP2019547605 A JP 2019547605A JP 2019547605 A JP2019547605 A JP 2019547605A JP 7778468 B2 JP7778468 B2 JP 7778468B2
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JP2019536480A (ja
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カンパーナ，ダリオ
ビナニカ，ナターシャ
尚宏 神谷
ピン，イ，ティアン
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ナショナル ユニバーシティ オブ シンガポール
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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JP2019547605A 2016-11-22 2017-11-22 Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断 Active JP7778468B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023012793A JP2023059873A (ja) 2016-11-22 2023-01-31 Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断
JP2025004349A JP2025065142A (ja) 2016-11-22 2025-01-10 Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662425398P 2016-11-22 2016-11-22
US62/425,398 2016-11-22
US201762543696P 2017-08-10 2017-08-10
US62/543,696 2017-08-10
PCT/US2017/063048 WO2018098306A1 (en) 2016-11-22 2017-11-22 Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies

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JP7778468B2 true JP7778468B2 (ja) 2025-12-02

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JP2023012793A Pending JP2023059873A (ja) 2016-11-22 2023-01-31 Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断
JP2025004349A Pending JP2025065142A (ja) 2016-11-22 2025-01-10 Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断

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JP2025004349A Pending JP2025065142A (ja) 2016-11-22 2025-01-10 Ｔ細胞悪性腫瘍の免疫療法のためのｃｄ７発現およびキメラ抗原受容体の遮断

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US (4) US11440958B2 (enExample)
EP (1) EP3545082A4 (enExample)
JP (3) JP7778468B2 (enExample)
KR (2) KR102889007B1 (enExample)
CN (3) CN118581046A (enExample)
AU (3) AU2017363278B2 (enExample)
CA (1) CA3043752A1 (enExample)
NZ (1) NZ752984A (enExample)
SG (2) SG10201912387PA (enExample)
WO (1) WO2018098306A1 (enExample)

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