JP7769607B2 - ウシ乳汁単離粉末状エクソソーム、栄養組成物および方法 - Google Patents

ウシ乳汁単離粉末状エクソソーム、栄養組成物および方法

Info

Publication number
JP7769607B2
JP7769607B2 JP2022525659A JP2022525659A JP7769607B2 JP 7769607 B2 JP7769607 B2 JP 7769607B2 JP 2022525659 A JP2022525659 A JP 2022525659A JP 2022525659 A JP2022525659 A JP 2022525659A JP 7769607 B2 JP7769607 B2 JP 7769607B2
Authority
JP
Japan
Prior art keywords
exosomes
powdered
nutritional composition
composition
milk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022525659A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023500674A (ja
JP2023500674A5 (enExample
Inventor
ペドロサ，ジョゼ マリア ロペス
マルティネス，ジョージ ガルシア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2023500674A publication Critical patent/JP2023500674A/ja
Publication of JP2023500674A5 publication Critical patent/JP2023500674A5/ja
Application granted granted Critical
Publication of JP7769607B2 publication Critical patent/JP7769607B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13—Nucleic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1276—Globules of milk; Constituents thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2022525659A 2019-11-08 2020-11-05 ウシ乳汁単離粉末状エクソソーム、栄養組成物および方法 Active JP7769607B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382978 2019-11-08
EP19382978.5 2019-11-08
PCT/US2020/059155 WO2021092209A1 (en) 2019-11-08 2020-11-05 Bovine milk-isolated powdered exosomes, nutritional compositions and methods

Publications (3)

Publication Number Publication Date
JP2023500674A JP2023500674A (ja) 2023-01-10
JP2023500674A5 JP2023500674A5 (enExample) 2023-11-10
JP7769607B2 true JP7769607B2 (ja) 2025-11-13

Family

ID=68610122

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022525659A Active JP7769607B2 (ja) 2019-11-08 2020-11-05 ウシ乳汁単離粉末状エクソソーム、栄養組成物および方法

Country Status (11)

Country Link
US (1) US20220395535A1 (enExample)
EP (2) EP4054604B1 (enExample)
JP (1) JP7769607B2 (enExample)
CN (1) CN114615897A (enExample)
CA (1) CA3156527A1 (enExample)
DK (1) DK4054604T3 (enExample)
ES (1) ES3069472T3 (enExample)
IL (1) IL292703A (enExample)
MX (2) MX2022005462A (enExample)
PH (1) PH12022551086A1 (enExample)
WO (1) WO2021092209A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115361879A (zh) * 2020-04-03 2022-11-18 雅培制药有限公司 牛奶外泌体产品和方法、营养组合物和治疗方法
KR102559516B1 (ko) * 2020-08-31 2023-07-26 경희대학교 산학협력단 우유 엑소좀을 포함하는 갈색지방화 유도용 조성물
CN116036298B (zh) * 2021-10-28 2024-06-04 光武惠文生物科技(北京)有限公司 牛奶外泌体在制备药物载体中的应用
WO2023076144A1 (en) * 2021-10-29 2023-05-04 Abbott Laboratories Methods and compositions for improving insulin production and secretion
JP2025514761A (ja) * 2022-04-21 2025-05-09 アボット・ラボラトリーズ 糖尿病の発症を遅らせる又は糖尿病のリスクを軽減するための方法及び組成物
CN117618575A (zh) * 2022-08-25 2024-03-01 逸惟生物科技(北京)有限公司 一种牛奶外泌体制剂及其应用
CN115873786B (zh) * 2022-12-29 2025-03-25 陕西慧康生物科技有限责任公司 一种鲜乳中外泌体规模化提取方法
ES2977833A1 (es) 2023-01-17 2024-08-30 Univ Madrid Autonoma Procedimiento para la obtención de exosomas a partir de mazada, exosomas obtenidos y aplicaciones de los mismos
WO2024249615A1 (en) * 2023-05-31 2024-12-05 Abbott Laboratories Bovine milk exosomes for delivering vitamin d

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014134132A1 (en) 2013-02-26 2014-09-04 University Of Louisville Research Foundation, Inc. Milk-derived microvesicle compositions and related methods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2639726B2 (ja) * 1989-02-27 1997-08-13 森永乳業株式会社 水溶性食物繊維およびその製造法
US6596302B2 (en) * 2000-04-13 2003-07-22 Abbott Laboratories Infant formulas containing long-chain polyunsaturated fatty acids and uses thereof
EP1656839A1 (en) * 2004-11-11 2006-05-17 N.V. Nutricia Nutrition containing lipid blend
BR112013031086A2 (pt) * 2011-06-08 2016-11-29 Nestec Sa composições nutricionais tendo componentes de membrana de glóbulo de gordura de leite exógenos
EP2583562A1 (en) * 2011-10-21 2013-04-24 Nestec S.A. Use of whey protein micelles for infants at risk of obesity or diabetes
CN106455662A (zh) * 2014-06-03 2017-02-22 雅培制药有限公司 包含亲脂性活性成分的营养组合物
WO2016033695A1 (en) * 2014-09-05 2016-03-10 Exerkine Corporation Exosome isolation
US10874114B2 (en) * 2015-11-29 2020-12-29 Hadasit Medical Research Services And Development Ltd. Supplementation of milk formulas with microvesicles isolated from milk
IT201600109148A1 (it) * 2016-10-28 2018-04-28 Pharmaexceed Srl Processo per isolare e liofilizzare vescicole extracellulari
CN109468265B (zh) * 2018-11-06 2021-06-22 广州市创唯曦旺生物科技有限公司 一种提取乳外泌体的方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014134132A1 (en) 2013-02-26 2014-09-04 University Of Louisville Research Foundation, Inc. Milk-derived microvesicle compositions and related methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of Nutritional Biochemistry，2018年，Vol.59，pp.123-128, Supplemental Table

Also Published As

Publication number Publication date
CA3156527A1 (en) 2021-05-14
MX2022005462A (es) 2022-05-26
WO2021092209A1 (en) 2021-05-14
CN114615897A (zh) 2022-06-10
PH12022551086A1 (en) 2024-06-24
EP4054604A1 (en) 2022-09-14
EP4736670A1 (en) 2026-05-06
JP2023500674A (ja) 2023-01-10
EP4054604B1 (en) 2026-03-04
MX2026004694A (es) 2026-06-01
US20220395535A1 (en) 2022-12-15
IL292703A (en) 2022-07-01
ES3069472T3 (en) 2026-06-08
DK4054604T3 (da) 2026-05-26

Similar Documents

Publication Publication Date Title
EP4054604B1 (en) Bovine milk-isolated powdered exosomes, nutritional compositions and methods
AU2010293145B2 (en) Probiotic derived non-viable material for allergy prevention and treatment
RU2437581C2 (ru) Способ стимуляции целостности кишечного барьера после родов не через естественные родовые пути
CN109890222B (zh) 包含人乳低聚糖的个性化儿科营养产品
US9730969B2 (en) Nutritional compositions for promoting gut barrier function and ameliorating visceral pain
CN113662199A (zh) 用于预防胃肠道损伤和/或促进胃肠道愈合的人乳寡糖
WO2018237149A1 (en) Methods for increasing growth of beneficial bacteria in the gastrointestinal tract
EP3223826A1 (en) Infant formula with rrr-alpha-tocopherol, 2'-fucosyllactose, and a probiotic
CN108347986A (zh) 包含鼠李糖乳杆菌gg以及膳食丁酸和/或用于刺激内源性丁酸形成的化合物的营养组合物
JP2026076271A (ja) 筋萎縮を軽減および／または筋肉再生を促進する方法
JP2025514761A (ja) 糖尿病の発症を遅らせる又は糖尿病のリスクを軽減するための方法及び組成物
CN103929979A (zh) 包含麦芽三糖的组合物，和使用该组合物抑制脱水过程所造成的损伤的方法
RU2804305C2 (ru) Пищевая композиция, содержащая мочевину и неперевариваемые олигосахариды
HK40010133A (en) Personalized pediatric nutrition products comprising human milk oligosaccharides

Legal Events

Date Code Title Description
RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20220509

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20220524

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231101

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20231101

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20241119

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20241210

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250310

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250617

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250916

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20251014

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20251031

R150 Certificate of patent or registration of utility model

Ref document number: 7769607

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150