JP7737219B2 - 潰瘍性大腸炎を治療するための方法 - Google Patents

潰瘍性大腸炎を治療するための方法

Info

Publication number
JP7737219B2
JP7737219B2 JP2019505410A JP2019505410A JP7737219B2 JP 7737219 B2 JP7737219 B2 JP 7737219B2 JP 2019505410 A JP2019505410 A JP 2019505410A JP 2019505410 A JP2019505410 A JP 2019505410A JP 7737219 B2 JP7737219 B2 JP 7737219B2
Authority
JP
Japan
Prior art keywords
subject
pharmaceutical composition
weeks
treatment
clostridium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019505410A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019525944A (ja
JP2019525944A5 (cg-RX-API-DMAC7.html
Inventor
トーマス・ジュリアス・ボロディ
Original Assignee
フィンチ セラピューティクス ホールディングス エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by フィンチ セラピューティクス ホールディングス エルエルシー filed Critical フィンチ セラピューティクス ホールディングス エルエルシー
Publication of JP2019525944A publication Critical patent/JP2019525944A/ja
Publication of JP2019525944A5 publication Critical patent/JP2019525944A5/ja
Priority to JP2022186548A priority Critical patent/JP2023010890A/ja
Application granted granted Critical
Publication of JP7737219B2 publication Critical patent/JP7737219B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2019505410A 2016-08-03 2017-08-02 潰瘍性大腸炎を治療するための方法 Active JP7737219B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022186548A JP2023010890A (ja) 2016-08-03 2022-11-22 潰瘍性大腸炎を治療するための方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662370508P 2016-08-03 2016-08-03
US62/370,508 2016-08-03
US15/360,703 US20180036352A1 (en) 2016-08-03 2016-11-23 Methods for treating ulcerative colitis
US15/360,703 2016-11-23
PCT/US2017/045092 WO2018026913A1 (en) 2016-08-03 2017-08-02 Methods for treating ulcerative colitis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022186548A Division JP2023010890A (ja) 2016-08-03 2022-11-22 潰瘍性大腸炎を治療するための方法

Publications (3)

Publication Number Publication Date
JP2019525944A JP2019525944A (ja) 2019-09-12
JP2019525944A5 JP2019525944A5 (cg-RX-API-DMAC7.html) 2020-09-17
JP7737219B2 true JP7737219B2 (ja) 2025-09-10

Family

ID=61071386

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019505410A Active JP7737219B2 (ja) 2016-08-03 2017-08-02 潰瘍性大腸炎を治療するための方法
JP2022186548A Pending JP2023010890A (ja) 2016-08-03 2022-11-22 潰瘍性大腸炎を治療するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022186548A Pending JP2023010890A (ja) 2016-08-03 2022-11-22 潰瘍性大腸炎を治療するための方法

Country Status (7)

Country Link
US (5) US20180036352A1 (cg-RX-API-DMAC7.html)
EP (1) EP3493822A1 (cg-RX-API-DMAC7.html)
JP (2) JP7737219B2 (cg-RX-API-DMAC7.html)
CN (1) CN109803667A (cg-RX-API-DMAC7.html)
AU (1) AU2017306303B2 (cg-RX-API-DMAC7.html)
CA (1) CA3032004A1 (cg-RX-API-DMAC7.html)
WO (1) WO2018026913A1 (cg-RX-API-DMAC7.html)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3045383B1 (fr) 2015-12-18 2019-06-14 Maat Pharma Procede de lyophilisation d'un echantillon de microbiote fecal
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis
BR112019006041A2 (pt) 2016-09-27 2019-09-03 Board Of Regents, The University Of Texas System métodos para aprimorar a terapia de bloqueio do ponto de verificação imunológico por modulação do microbioma
CA3058943C (en) 2017-04-03 2023-10-17 Gusto Global, Llc Rational design of microbial-based biotherapeutics
US11865145B2 (en) 2017-08-07 2024-01-09 Finch Therapeutics Holdings Llc Compositions and methods for maintaining and restoring a healthy gut barrier
KR102118203B1 (ko) * 2018-03-06 2020-06-02 주식회사 엠디헬스케어 코프로코커스 속 세균 유래 나노소포 및 이의 용도
FR3078627B1 (fr) * 2018-03-09 2020-11-13 Maat Pharma Procedure de collecte de selles et procede de preparation d'un echantillon pour transplantation de microbiote fecal
EP3597202A1 (en) * 2018-07-20 2020-01-22 Maat Pharma Fecal microbiota composition, for use in reducing treatment-induced inflammation
WO2020069280A1 (en) * 2018-09-27 2020-04-02 Crestovo Holdings Llc Compositions and methods for treating epilepsy and related disorders
CN109394795A (zh) * 2018-10-23 2019-03-01 上海市第十人民医院 一种肠菌胶囊制备方法及肠菌胶囊
CN113905749A (zh) * 2019-01-16 2022-01-07 德克萨斯大学系统董事会 用于治疗免疫检查点抑制剂相关结肠炎的方法和组合物
JP2022541795A (ja) 2019-07-19 2022-09-27 フィンチ セラピューティクス ホールディングス エルエルシー 胃腸障害の治療のための方法および産物
US20230087012A1 (en) * 2020-02-14 2023-03-23 Cornell University Transferable microbiota for the treatment of ulcerative colitis
US20220120746A1 (en) * 2020-03-18 2022-04-21 Sabine Hazan Methods of Determining Susceptibility to COVID-19 Infection
US11744866B2 (en) * 2020-03-18 2023-09-05 Sabine Hazan Methods of preventing and treating COVID-19 infection with probiotics
CA3183811A1 (en) * 2020-06-29 2022-01-06 Marla C. DUBINSKY Systems and methods for evaluating a subject for inflammatory bowel disease management
CN111888381A (zh) * 2020-09-18 2020-11-06 广西细微生物科技有限责任公司 一种肠道微生物移植工艺
CA3202036A1 (en) * 2020-12-23 2022-06-30 Herve Affagard Method of expanding a complex community of microorganisms
CN113509494A (zh) * 2021-09-06 2021-10-19 南京医科大学 普氏菌在制备治疗胆汁淤积性疾病的药物中的应用
CN114246886B (zh) * 2021-12-24 2023-05-30 山西大学 规则粪球菌在制备预防和治疗急性结肠炎的制剂中的应用
CN115478031B (zh) * 2022-09-28 2025-04-18 中国科学院深圳先进技术研究院 防治炎症性肠病的胆汁酸代谢菌及其应用
KR20240114298A (ko) * 2023-01-12 2024-07-23 에스엔제이 파마 인크 감염 저항성 장내 균주 및 그 용도
CN119868571B (zh) * 2025-01-23 2025-11-21 浙江大学 扭链瘤胃球菌及其修饰菌在制备治疗溃疡性结肠炎的产品中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004501095A (ja) 2000-05-11 2004-01-15 アンスティテュ　ナショナール　ド　ラ　ルシェルシュ　アグロノミク 消化器系障害の予防または治療のための水素依存性酢酸生成株の使用
JP2016521704A (ja) 2013-06-05 2016-07-25 レビオティクス インコーポレイテッドＲｅｂｉｏｔｉｘ，Ｉｎｃ． 微生物叢回復療法（ｍｒｔ）、組成物および製造方法

Family Cites Families (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2828E (fr) 1901-08-19 1904-06-30 Louis Emile Albert Durand Machine agricole dénommée gratteuse-bineuse-sulfateuse, destinée à travailler et sulfater simultanément les vignes ou tous végétaux plantés en rang
FR1275E (fr) 1902-02-21 1903-07-01 Buil Francois Sebastien Joseph Système de fixation des poignées de vélocipèdes
FR2427E (fr) 1903-08-19 1904-04-07 Paul Steinmetz Carburateur doseur, pour moteurs à explosion
FR5528E (fr) 1905-03-16 1906-05-02 Farcot Freres Et Cie Soc Perfectionnements aux turbines à vapeur ou à gaz
DE1118403B (de) 1960-01-27 1961-11-30 Hoechst Ag Verfahren zur Gewinnung von antitumorwirksamen Sporen
FR1275M (fr) 1961-05-06 1962-05-02 Rene Roger Médicament a base de colibacilles vivants.
BE634858A (cg-RX-API-DMAC7.html) 1962-07-19 1900-01-01
FR2828M (fr) 1963-03-01 1964-11-02 Lucien Nouvel Médicament renfermant des colibacilles antibiorésistants.
FR5528M (cg-RX-API-DMAC7.html) 1965-10-01 1967-11-13
GB1271674A (en) 1968-07-09 1972-04-26 Nisshin Flour Milling Co Process and preparation for treating diarrhoea in pigs
SE371209B (cg-RX-API-DMAC7.html) 1969-10-13 1974-11-11 Cernelle Ab
DE2134179A1 (de) 1971-07-09 1973-01-25 Rolf Dr Schuler Bifidobakterien enthaltendes praeparat und verfahren zur herstellung desselben
FR2244464A1 (en) 1973-06-26 1975-04-18 Serozym Laboratoires Yeast, lacto- and colibacillus based compsns - used to modify intestinal flora, treat colitis and digestive disorders, etc.
US4098728A (en) 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4335107A (en) 1978-06-05 1982-06-15 Snoeyenbos Glenn H Mixture to protect poultry from salmonella
CH637297A5 (fr) 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
US4309782A (en) 1980-09-11 1982-01-12 Esteban Paulin Device for collecting fecal specimens
US4536409A (en) 1981-01-23 1985-08-20 American Can Company Oxygen scavenger
US4394377A (en) 1981-07-31 1983-07-19 Syntex (U.S.A.) Inc. Ruminant animal performance by co-administering choline and propionate enchancers
US4452779A (en) 1982-02-03 1984-06-05 Cockerill Vernon Composition and method of treating lactating mammals
FI840816A0 (fi) 1984-03-01 1984-03-01 Farmos Oy Bakteriepreparat
JPS615022A (ja) 1984-06-19 1986-01-10 Advance Res & Dev Co Ltd 腸内細菌叢改善剤
US4892731A (en) 1986-12-11 1990-01-09 Tadashi Arai Biological intestinal antiseptics
IL86859A (en) 1987-07-10 1991-12-15 E Z Em Inc Aqueous cathartic solution containing inorganic salts
US4948734A (en) 1987-08-12 1990-08-14 Mycogen Corporation Novel isolates of bacillus thuringiensis having activity against nematodes
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
CA1333564C (en) 1988-08-02 1994-12-20 Thomas Julius Borody Treatment of gastro-intestinal disorders
US5213807A (en) 1990-05-03 1993-05-25 Chemburkar Pramod B Pharmaceutical composition containing ibuprofen and a prostaglandin
JP2961184B2 (ja) 1990-05-07 1999-10-12 ミヤリサン株式会社 クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物
US5266315A (en) 1990-05-07 1993-11-30 Kabushiki Kaisha Miyarisan Seibutsu Igaku Kenkyusho Composite for Clostridium difficile diarrhea and pseudomembranous colitis
GB9107305D0 (en) 1991-04-08 1991-05-22 Unilever Plc Probiotic
JP3047143B2 (ja) 1992-04-24 2000-05-29 堀井薬品工業株式会社 腸管洗浄液用組成物及び腸管洗浄液
JP3850891B2 (ja) 1994-03-01 2006-11-29 ゼリア新薬工業株式会社 緩下効果を有する組成物
US6984513B2 (en) 1994-03-03 2006-01-10 The Board Of Trustees Of The Leland Stanford Junior University Anaerobe targeted enzyme-mediated prodrug therapy
JPH07242557A (ja) 1994-03-03 1995-09-19 Ss Pharmaceut Co Ltd 乳酸菌含有瀉下薬組成物
NZ287420A (en) 1994-05-26 1997-12-19 Bracco Spa Lactobacillus strains with enhanced gut adhesion
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
AUPM864894A0 (en) 1994-10-07 1994-11-03 Borody, Thomas Julius Treatment of bowel-dependent neurological disorders
US5800821A (en) 1995-03-10 1998-09-01 New England Medical Center Hospitals, Inc. Bacterial spores as a heat stable vaccine delivery system
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US5858356A (en) 1995-12-21 1999-01-12 Abbott Laboratories Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals
US5902578A (en) 1996-03-25 1999-05-11 Abbott Laboratories Method and formula for the prevention of diarrhea
US5837238A (en) 1996-06-05 1998-11-17 Biogaia Biologics Ab Treatment of diarrhea
US6087386A (en) 1996-06-24 2000-07-11 Merck & Co., Inc. Composition of enalapril and losartan
WO1998013068A1 (fr) 1996-09-26 1998-04-02 Vladimir Borisovich Kuperman Medicament prophylactique 'trisan'
US5948787A (en) 1997-02-28 1999-09-07 Alza Corporation Compositions containing opiate analgesics
US6162464A (en) 1997-03-31 2000-12-19 Inkine Pharmaceutical, Inc. Non-aqueous colonic purgative formulations
US7374753B1 (en) 1997-06-03 2008-05-20 Ganeden Biotech, Inc. Probiotic lactic acid bacterium to treat bacterial infections associated with SIDS
US6428783B1 (en) 1998-03-11 2002-08-06 Medtech Center, Inc. Bank of autochthonous strains of microorganisms and methods of its use for recovery of intestinal microbiocenosis of the men
US5902743A (en) 1998-03-20 1999-05-11 Wisconsin Alumni Research Foundation Probiotic bifidobacterium strain
AU771630B2 (en) 1998-05-06 2004-04-01 Keijiro Nakamura Microbial culture liquors containing microorganisms differing in characteristics and living in symbiosis and metabolites thereof, carriers and adsorbents containing the active components of the culture liquors and utilization of the same
US6368591B2 (en) 1998-05-15 2002-04-09 Shanghai Sine Pharmaceutical Corporation Ltd. Beneficial microbe composition, new protective materials for the microbes, method to prepare the same and uses thereof
AT407008B (de) 1998-08-06 2000-11-27 Viernstein Helmut Dr Formulierungen mit probiotisch wirksamen mikroorganismen
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
SK3482001A3 (en) 1998-09-17 2002-02-05 Baxter Healthcare Sa Streptococcal c beta protein compositions
EP1005863A1 (en) 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof
CA2354054C (en) 1998-12-11 2011-04-12 Urex Biotech, Inc. Oral administration of lactobacillus for the treatment and prevention of urogenital infection
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
CN1183904C (zh) 1999-02-26 2005-01-12 盐野义制药株式会社 改进了服用性的咀嚼型软胶囊剂及其制法
US20040170617A1 (en) 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
US20040062757A1 (en) 2001-06-05 2004-04-01 Finegold Sydney M. Method of testing gastrointestinal diseases associated with species of genus clostridium
US6756032B1 (en) 2000-07-12 2004-06-29 The Procter & Gamble Company Method to enhance and/or prolong the effects of a primary challenge to a responsive system with a secondary challenge
EP1303285A2 (en) 2000-07-17 2003-04-23 Chr. Hansen A/S Methods and formulations with probiotic microorganisms and medicaments
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
US7214370B2 (en) 2000-12-18 2007-05-08 Probiohealth, Llc Prebiotic and preservative uses of oil-emulsified probiotic encapsulations
US6790453B2 (en) 2001-03-14 2004-09-14 Mccormick & Company, Inc. Encapsulation compositions and process for preparing the same
US7815956B2 (en) 2001-04-27 2010-10-19 Pepsico Use of erythritol and D-tagatose in diet or reduced-calorie beverages and food products
PT1411900E (pt) 2001-06-01 2010-10-11 Pozen Inc Composições farmacêuticas para a entrega coordenada de aines
US7846475B2 (en) 2001-07-05 2010-12-07 Wakunaga Pharmaceutical Co., Ltd. Soft capsules
PE20030284A1 (es) 2001-07-26 2003-05-01 Alimentary Health Ltd Cepas de bifidobacterium
US20030092724A1 (en) 2001-09-18 2003-05-15 Huaihung Kao Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic
GB0124580D0 (en) 2001-10-12 2001-12-05 Univ Reading New composition
RU2295344C2 (ru) 2002-04-05 2007-03-20 Еуро-Селтик С.А. Фармацевтический препарат, содержащий оксикодон и налоксон
CA2391422A1 (en) 2002-07-12 2004-01-12 David William Molloy Rifampin (rifadin, rimactone, rifampicin) and doxycycline, (doryx, vibramycin) and the tetracyclines and other compounds currently classified as antibiotics and anti-tuberculous drugs as a treatment to prevent, modify disease progression and/or improve symptoms for neurodegenerative diseases including alzheimers disease, lewy body dementia, schizophrenia,...
IL152127A0 (en) 2002-10-06 2003-05-29 Bio Balance Corp Probiotic compositions for the treatment of inflammatory bowel disease
BRPI0412979A (pt) 2003-08-18 2006-10-03 Bio Balance Corp composição probiótica lìquida, método para a preparação da composição probiótica lìquida e método para tratar um paciente
US7749509B2 (en) 2003-08-29 2010-07-06 Cobb And Company, Llp Treatment of autism using probiotic composition
US20060177424A1 (en) 2003-08-29 2006-08-10 Cobb Mark L Treatment of disease states and adverse physiological conditions utilizing anti-fungal compositions
US8192733B2 (en) 2003-08-29 2012-06-05 Cobb & Associates Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US7759105B2 (en) 2003-08-29 2010-07-20 Cobb & Company, Llp Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US8016816B2 (en) 2003-09-09 2011-09-13 Convatec Technologies Inc. Fecal management appliance and method and apparatus for introducing same
US7541091B2 (en) 2004-05-18 2009-06-02 M & G Usa Corporation Compartmentalized resin pellets for oxygen scavenging
JP4709838B2 (ja) 2004-08-05 2011-06-29 アニドラル エス．アール．エル． 葉酸産生ビフィドバクテリウム菌株、製剤およびこれらの用途
ATE367821T1 (de) 2004-08-05 2007-08-15 Anidral Srl Folsäure produzierende bifidobacterium bakterienstämme, ihre formulierungen und verwendung
US20060076536A1 (en) 2004-09-29 2006-04-13 Barshied Scott R Oxygen scavenging pharmaceutical package and methods for making same
US20060115465A1 (en) 2004-10-29 2006-06-01 Macfarlane George Treatment of gastrointestinal disorders
US7382263B2 (en) 2005-05-20 2008-06-03 Dow Global Technologies Inc. Oral drug compliance monitoring using radio frequency identification tags
US20060275223A1 (en) 2005-06-02 2006-12-07 Burr James B Erythritol compositions for teeth and gums
TWI362949B (en) 2005-09-13 2012-05-01 Bion Tech Inc Intestines dissolving nature is able to bear the hydrochloric acid in gastric juice and wrap up the benefit covered and grow the fungus of makes up
EP1970055B1 (en) 2005-12-29 2010-11-24 Osmotica Kereskedelmi És Szolgáltató Kft Multi-layered tablet with triple release combination
JP5006567B2 (ja) 2006-04-14 2012-08-22 花王株式会社 口腔用固形製剤
US7998510B2 (en) 2006-08-17 2011-08-16 C. B. Fleet Company, Inc. Low dose colonic cleansing system
JP2008106066A (ja) 2006-09-25 2008-05-08 Tashiro Yasuaki サポニン及び生菌を含有する組成物
DE102006062250A1 (de) 2006-12-22 2008-06-26 Roland Saur-Brosch Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden
AU2008219818B2 (en) 2007-03-01 2013-06-27 Probi Ab Use of Lactobacillus plantarum for increasing bacterial diversity
MX2009010419A (es) 2007-03-28 2010-02-18 Alimentary Health Ltd Cepas de bacterias bifidas probioticas.
MY146595A (en) 2007-03-28 2012-08-30 Alimentary Health Ltd Probiotic bifidobacterium strains
WO2008148798A2 (en) 2007-06-04 2008-12-11 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
US10406105B2 (en) 2007-06-06 2019-09-10 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
US20100184785A1 (en) 2007-06-06 2010-07-22 Basf Se Pharmaceutical formulation for the production of chewable tablets and lozenges
AU2008281850B2 (en) 2007-07-27 2013-10-10 Cargill, Incorporated Micronization of polyols
EP2030623A1 (en) 2007-08-17 2009-03-04 Nestec S.A. Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria
US20110008554A1 (en) 2007-08-31 2011-01-13 Invista North America S.A.R.I. Oxygen scavenging plastic compositions
JP5537943B2 (ja) 2007-09-27 2014-07-02 田辺三菱製薬株式会社 速崩壊性固形製剤
CA2703501C (en) 2007-10-01 2017-06-13 Laboratorios Lesvi, S.L. Orodispersible tablets
CA2702935A1 (en) 2007-10-19 2009-04-23 Purdue Research Foundation Solid formulations of crystalline compounds
JP5327984B2 (ja) 2007-10-20 2013-10-30 ユニベルシテ・ド・リエージュ ビフィズス菌の種
AU2008317000B2 (en) 2007-10-26 2014-10-23 Brenda E. Moore Probiotic compositions and methods for inducing and supporting weight loss
JP5258268B2 (ja) 2007-11-19 2013-08-07 フロイント産業株式会社 球形粒の製造方法
WO2009084678A1 (ja) 2007-12-28 2009-07-09 Sawai Pharmaceutical Co., Ltd. 口腔内崩壊錠およびその製造方法
HRP20200284T1 (hr) 2008-10-02 2020-07-10 Salix Pharmaceuticals, Ltd. Postupci liječenja hepatičke encefalopatije
US20100178413A1 (en) 2008-12-17 2010-07-15 Mark Gorris Food-based Supplement Delivery System
WO2010103132A1 (es) 2009-03-10 2010-09-16 Hero España, S.A. Aislamiento, identificación y caracterización de cepas con actividad probiótica a partir de heces de lactantes alimentados exclusivamente con leche materna
US20100255231A1 (en) 2009-04-01 2010-10-07 Multisorb Technologies, Inc. Oxygen scavenging films
KR101821417B1 (ko) 2009-04-30 2018-01-23 인트랙슨 액토바이오틱스 엔.브이. 유산균의 냉동건조에 사용하기 위한 냉동보호제
US20100285164A1 (en) 2009-05-11 2010-11-11 Jrs Pharma Orally Disintegrating Excipient
WO2010138439A1 (en) 2009-05-28 2010-12-02 Aptapharma, Inc. Multiparticulate controlled-release selective serotonin reuptake inhibitor formulations
CN201441672U (zh) 2009-07-14 2010-04-28 赵伟华 一次性灌肠装置
US20110045222A1 (en) 2009-08-19 2011-02-24 Eastman Chemical Company Oxygen-scavenging polymer blends suitable for use in packaging
GB0916335D0 (en) 2009-09-17 2009-10-28 Martin W J Medicaments
US20110081320A1 (en) 2009-10-06 2011-04-07 Nubiome, Inc. Treatment/Cure of Autoimmune Disease
US20120276149A1 (en) 2009-10-15 2012-11-01 Dan Littman Methods for modulating bacterial infection
US20110218216A1 (en) 2010-01-29 2011-09-08 Kumaravel Vivek Extended release pharmaceutical composition of donepezil
US7888062B1 (en) 2010-02-01 2011-02-15 Microbios, Inc. Process and composition for the manufacture of a microbial-based product
DK3564357T3 (da) 2010-02-01 2022-06-20 Rebiotix Inc Bakterieterapi mod clostridium difficile colitis
US8853269B2 (en) 2010-02-04 2014-10-07 Copperhead Chemical Company Inc. Composition and method for treating infections and promoting intestinal health
CA2792647A1 (en) 2010-03-10 2011-09-15 Nogra Pharma Limited Compositions for colon lavage and methods of making and using same
US9707207B2 (en) 2010-05-26 2017-07-18 The United States Of America As Represented By The Department Of Veterans Affairs Method for diagnosing, preventing, and treating neurological diseases
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物
RU2013109251A (ru) 2010-08-04 2014-09-10 Томас Джулиус БОРОДИ Композиции для трансплантации фекальной флоры и способы их получения и применения и устройства для их доставки
KR20140033309A (ko) 2010-10-04 2014-03-18 브리티쉬 콜롬비아 캔써 에이전시 브랜치 위장 암을 진단하기 위해 위장의 샘플에서의 푸소박테리움의 검출
PL3072524T3 (pl) 2010-10-07 2018-06-29 California Institute Of Technology Probiotyczne terapie dla autyzmu
WO2014152484A1 (en) * 2013-03-14 2014-09-25 Regents Of The University Of Minnesota Freeze dried fecal microbiota for use in fecal microbial transplantation
US20150374761A1 (en) 2011-03-09 2015-12-31 Regents Of The University Of Minnesota Freeze dried fecal microbiota for use in fecal microbial transplantation
EP3610881A1 (en) * 2011-03-09 2020-02-19 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
WO2013037068A1 (en) 2011-09-14 2013-03-21 Queen's University At Kingston Method for treatment of disorders of the gastrointestinal system
CA2850437A1 (en) 2011-10-11 2013-04-18 Achim Biotherapeutics Ab Composition comprising anaerobically cultivated human intestinal microbiota
CN104160014A (zh) 2011-12-01 2014-11-19 国立大学法人东京大学 诱导调节性t细胞的增殖或积累的人源细菌
US9176026B2 (en) 2011-12-15 2015-11-03 Pureflora, Inc. Device for the collection, refinement, and administration of gastrointestinal microflora
CA2872149C (en) 2012-05-02 2019-03-19 Charles River Laboratories, Inc. Viability staining method
WO2013176774A1 (en) 2012-05-25 2013-11-28 Arizona Board Of Regents Microbiome markers and therapies for autism spectrum disorders
US10220089B2 (en) 2012-08-29 2019-03-05 California Institute Of Technology Diagnosis and treatment of autism spectrum disorder
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
WO2014078911A1 (en) * 2012-11-26 2014-05-30 Borody Thomas J Compositions for the restoration of a fecal microbiota and methods for making and using them
EP2956006A4 (en) 2013-02-04 2017-02-22 Seres Therapeutics, Inc. Methods of populating a gastrointestinal tract
WO2014152338A1 (en) 2013-03-14 2014-09-25 Kabadi Mohan Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
EP2991649B1 (en) 2013-04-30 2020-06-03 Thomas Julius Borody Compositions for treating obsessive-compulsive disorder
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
EP3019181A4 (en) 2013-07-09 2016-09-21 Puretech Ventures Llc COMPOSITIONS WITH COMBINATIONS OF BIOACTIVE MOLECULARS DERIVED FROM MICROBOTS FOR TREATING DISEASES
WO2015051323A1 (en) 2013-10-03 2015-04-09 Trustees Of The University Of Pennsylvania Compositions comprising a defined microbiome and methods of use thereof
AU2014352643A1 (en) 2013-11-25 2016-06-30 Seres Therapeutics, Inc. Synergistic bacterial compositions and methods of production and use thereof
EP3082431A4 (en) 2013-12-16 2017-11-15 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
WO2016183577A1 (en) 2015-05-14 2016-11-17 Crestovo Llc Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
CN114470009A (zh) 2015-05-22 2022-05-13 亚利桑那大学董事会 用于治疗自闭症谱系障碍及相关症状的方法
BR112018008358A2 (pt) 2015-10-26 2019-04-24 Crestovo Holdings Llc ?composições e métodos para terapia relacionada à microbiota fecal?
CA3016059A1 (en) 2016-03-04 2017-09-08 The Regents Of The University Of California Microbial consortium and uses thereof
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004501095A (ja) 2000-05-11 2004-01-15 アンスティテュ　ナショナール　ド　ラ　ルシェルシュ　アグロノミク 消化器系障害の予防または治療のための水素依存性酢酸生成株の使用
JP2016521704A (ja) 2013-06-05 2016-07-25 レビオティクス インコーポレイテッドＲｅｂｉｏｔｉｘ，Ｉｎｃ． 微生物叢回復療法（ｍｒｔ）、組成物および製造方法

Also Published As

Publication number Publication date
EP3493822A1 (en) 2019-06-12
CA3032004A1 (en) 2018-02-08
JP2023010890A (ja) 2023-01-20
JP2019525944A (ja) 2019-09-12
US20180036352A1 (en) 2018-02-08
US11071759B2 (en) 2021-07-27
US12390496B2 (en) 2025-08-19
AU2017306303A1 (en) 2019-02-14
CN109803667A (zh) 2019-05-24
US10195235B2 (en) 2019-02-05
US20180125899A1 (en) 2018-05-10
US20210330717A1 (en) 2021-10-28
US20200113949A1 (en) 2020-04-16
AU2017306303B2 (en) 2025-01-02
US20190175665A1 (en) 2019-06-13
US10561690B2 (en) 2020-02-18
WO2018026913A1 (en) 2018-02-08

Similar Documents

Publication Publication Date Title
JP7737219B2 (ja) 潰瘍性大腸炎を治療するための方法
JP7273082B2 (ja) 自閉症スペクトラム障害および関連する症候を治療するための方法
US20210106629A1 (en) Compositions and Methods for Treating Inflammatory Bowel Diseases (IBDs) and Other Disorders
JP2018535254A (ja) 便微生物叢関連療法のための組成物及び方法
US20210121503A1 (en) Fecal microbiota transplantation for treating ulcerative colitis
US11213549B2 (en) Compositions and method for treating primary sclerosing cholangitis and related disorders
US20210275603A1 (en) Compositions and Methods for Treating Irritable Bowel Syndrome and Related Disorders
US20180099011A1 (en) Compositions and Methods for Treating Irritable Bowel Syndrome and Related Disorders
US20200188449A1 (en) Compositions and Methods for Treating Chronic Fatigue Syndrome and Related Disorders
WO2021097288A1 (en) Compositions and methods for treating neurodegenerative diseases
US20240173360A1 (en) Compositions and methods for treating epilepsy and related disorders
US20200197449A1 (en) Compositions and Methods for Treating Alopecia and Related Disorders
US20180099013A1 (en) Compositions and Methods for Treating Chronic Fatigue Syndrome and Related Disorders
HK40009325A (en) Methods for treating ulcerative colitis
WO2021142347A1 (en) Compositions and methods for non-alcoholic steatohepatitis (nash)

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200803

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20200803

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210802

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20211102

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220202

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220523

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220808

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20221003

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221122

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20230116

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230516

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20230619

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20230707

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250611

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20250829

R150 Certificate of patent or registration of utility model

Ref document number: 7737219

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150