JP7682605B2 - 過活動膀胱を治療するためのビベグロンの使用 - Google Patents

過活動膀胱を治療するためのビベグロンの使用 Download PDF

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JP7682605B2
JP7682605B2 JP2019567995A JP2019567995A JP7682605B2 JP 7682605 B2 JP7682605 B2 JP 7682605B2 JP 2019567995 A JP2019567995 A JP 2019567995A JP 2019567995 A JP2019567995 A JP 2019567995A JP 7682605 B2 JP7682605 B2 JP 7682605B2
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pharmaceutical composition
vibegron
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JP2020522560A (ja
JP2020522560A5 (enExample
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シー.ピシテッリ ステファン
マッド ポール
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Urovant Sciences GmbH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019567995A 2017-06-06 2018-06-06 過活動膀胱を治療するためのビベグロンの使用 Active JP7682605B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023030625A JP2023071826A (ja) 2017-06-06 2023-03-01 過活動膀胱を治療するためのビベグロンの使用
JP2025005498A JP2025063196A (ja) 2017-06-06 2025-01-15 過活動膀胱を治療するためのビベグロンの使用

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762515996P 2017-06-06 2017-06-06
US62/515,996 2017-06-06
US201862635146P 2018-02-26 2018-02-26
US62/635,146 2018-02-26
US201862637961P 2018-03-02 2018-03-02
US62/637,961 2018-03-02
PCT/IB2018/054069 WO2018224989A1 (en) 2017-06-06 2018-06-06 Use of vibegron to treat overactive bladder

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2023030625A Division JP2023071826A (ja) 2017-06-06 2023-03-01 過活動膀胱を治療するためのビベグロンの使用
JP2025005498A Division JP2025063196A (ja) 2017-06-06 2025-01-15 過活動膀胱を治療するためのビベグロンの使用

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JP2020522560A JP2020522560A (ja) 2020-07-30
JP2020522560A5 JP2020522560A5 (enExample) 2021-07-26
JP7682605B2 true JP7682605B2 (ja) 2025-05-26

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JP2019567995A Active JP7682605B2 (ja) 2017-06-06 2018-06-06 過活動膀胱を治療するためのビベグロンの使用
JP2023030625A Pending JP2023071826A (ja) 2017-06-06 2023-03-01 過活動膀胱を治療するためのビベグロンの使用
JP2025005498A Pending JP2025063196A (ja) 2017-06-06 2025-01-15 過活動膀胱を治療するためのビベグロンの使用

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JP2023030625A Pending JP2023071826A (ja) 2017-06-06 2023-03-01 過活動膀胱を治療するためのビベグロンの使用
JP2025005498A Pending JP2025063196A (ja) 2017-06-06 2025-01-15 過活動膀胱を治療するためのビベグロンの使用

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US (1) US12102638B2 (enExample)
EP (2) EP3634420A1 (enExample)
JP (3) JP7682605B2 (enExample)
KR (2) KR20200012949A (enExample)
CN (3) CN117695287A (enExample)
AU (2) AU2018282104B2 (enExample)
BR (1) BR112019025636A2 (enExample)
CA (1) CA3064989A1 (enExample)
CL (1) CL2019003533A1 (enExample)
IL (2) IL317220A (enExample)
MX (1) MX2022015629A (enExample)
PH (1) PH12019502651A1 (enExample)
WO (1) WO2018224989A1 (enExample)
ZA (1) ZA202000028B (enExample)

Families Citing this family (5)

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CA3085745A1 (en) * 2017-12-21 2019-06-27 Kyorin Pharmaceutical Co., Ltd. An agent for treating nocturnal pollakiuria
EP3890743A1 (en) * 2018-12-05 2021-10-13 Urovant Sciences GmbH Vibegron for the treatment of overactive bladder symptoms
JP2022524576A (ja) * 2019-03-18 2022-05-09 ウロバント サイエンシズ ゲーエムベーハー 過活動膀胱を処置するためのビベグロンの使用
DE102020124101A1 (de) 2020-02-04 2021-08-05 Samsung Electronics Co., Ltd. Elektronische vorrichtung mit einer speichervorrichtung und trainingsverfahren
TW202239412A (zh) * 2020-12-22 2022-10-16 瑞士商優洛凡特科學公司 使用維貝格隆(vibegron)並監測地高辛(digoxin)以治療膀胱過動症的方法

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PH12019502651A1 (en) 2020-06-08
EP3634420A1 (en) 2020-04-15
AU2024204591A1 (en) 2024-07-18
CN117695287A (zh) 2024-03-15
KR20250099259A (ko) 2025-07-01
JP2023071826A (ja) 2023-05-23
AU2018282104A1 (en) 2019-12-12
WO2018224989A1 (en) 2018-12-13
IL317220A (en) 2025-01-01
BR112019025636A2 (pt) 2020-08-25
EP4410295A3 (en) 2024-10-16
EP4410295A2 (en) 2024-08-07
KR20200012949A (ko) 2020-02-05
CA3064989A1 (en) 2018-12-13
MX2022015629A (es) 2023-01-11
JP2020522560A (ja) 2020-07-30
CN110869022A (zh) 2020-03-06
CN117695286A (zh) 2024-03-15
CL2019003533A1 (es) 2020-06-26
IL271164A (en) 2020-01-30
ZA202000028B (en) 2025-09-25
US20210077495A1 (en) 2021-03-18
US12102638B2 (en) 2024-10-01
JP2025063196A (ja) 2025-04-15
AU2018282104B2 (en) 2024-07-11

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