PL3365321T3 - Jon obojnaczy solabegronu i jego zastosowania - Google Patents
Jon obojnaczy solabegronu i jego zastosowaniaInfo
- Publication number
- PL3365321T3 PL3365321T3 PL16858451.4T PL16858451T PL3365321T3 PL 3365321 T3 PL3365321 T3 PL 3365321T3 PL 16858451 T PL16858451 T PL 16858451T PL 3365321 T3 PL3365321 T3 PL 3365321T3
- Authority
- PL
- Poland
- Prior art keywords
- solabegron zwitterion
- solabegron
- zwitterion
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562245656P | 2015-10-23 | 2015-10-23 | |
| US201562245670P | 2015-10-23 | 2015-10-23 | |
| US201662345574P | 2016-06-03 | 2016-06-03 | |
| US201662345357P | 2016-06-03 | 2016-06-03 | |
| US201662345327P | 2016-06-03 | 2016-06-03 | |
| PCT/US2016/058516 WO2017070689A2 (en) | 2015-10-23 | 2016-10-24 | Solabegron zwitterion and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3365321T3 true PL3365321T3 (pl) | 2024-03-25 |
Family
ID=58557973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16858451.4T PL3365321T3 (pl) | 2015-10-23 | 2016-10-24 | Jon obojnaczy solabegronu i jego zastosowania |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US10065922B2 (pl) |
| EP (1) | EP3365321B1 (pl) |
| CN (2) | CN108290824B (pl) |
| CA (1) | CA3001850A1 (pl) |
| DK (1) | DK3365321T3 (pl) |
| ES (1) | ES2967863T3 (pl) |
| FI (1) | FI3365321T3 (pl) |
| IL (2) | IL258856B2 (pl) |
| PL (1) | PL3365321T3 (pl) |
| PT (1) | PT3365321T (pl) |
| WO (1) | WO2017070689A2 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| AU2015358378A1 (en) | 2014-12-03 | 2017-06-29 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
| IL258856B2 (en) | 2015-10-23 | 2024-07-01 | Velicept Therapeutics Inc | Solabegron zwitterion and uses thereof |
| US10298650B2 (en) * | 2016-04-20 | 2019-05-21 | Vasona Networks, Inc. | Maximum sustainable encoding bit rates for video downloads |
| JP7682605B2 (ja) | 2017-06-06 | 2025-05-26 | ウロバント サイエンシズ ゲゼルシャフト ミット ベシュレンクター ハフトゥング | 過活動膀胱を治療するためのビベグロンの使用 |
| TW202438077A (zh) | 2018-12-05 | 2024-10-01 | 瑞士商優洛凡特科學公司 | 維貝隆(vibegron)於治療患有良性前列腺增生之男性中膀胱過動症症狀之用途 |
| CN111925294A (zh) * | 2020-07-06 | 2020-11-13 | 济南大学 | 一种托特罗定帕莫酸盐及其制备方法 |
| CN117529310A (zh) * | 2021-03-31 | 2024-02-06 | B3Ar治疗股份有限公司 | 微粒化的索拉贝隆的组合物及其使用方法 |
Family Cites Families (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL267508A (pl) | 1960-07-26 | |||
| EP0006735B1 (en) | 1978-06-28 | 1983-06-15 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| GB8519154D0 (en) | 1985-07-30 | 1985-09-04 | Ici Plc | Aromatic ethers |
| DE3934436A1 (de) | 1989-06-01 | 1991-04-18 | Thomae Gmbh Dr K | 2-hydroxy-n-propylamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5061727A (en) | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| NO179246C (no) | 1991-11-20 | 1996-09-04 | Sankyo Co | Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav |
| AU2737295A (en) | 1994-06-09 | 1996-01-04 | Glaxo Group Limited | Phenethanolamine derivatives and their use as atypical beta-adrenoceptor agonists |
| US5677346A (en) | 1995-01-31 | 1997-10-14 | Sepracor, Inc. | Treating urinary incontinence using (S)-desethyloxybutynin |
| CZ126598A3 (cs) | 1995-10-26 | 1998-09-16 | Mitsubishi-Tokyo Pharmaceuticals, Inc. | Fenylethanolaminové sloučeniny, způsob jejich výroby a farmaceutické prostředky s jejich obsahem |
| US6123961A (en) | 1996-09-25 | 2000-09-26 | Bridge Pharma, Inc. | Treating urinary incontinence with (R)-desethyloxybutynin and (R)-oxybutynin |
| GB9812709D0 (en) | 1998-06-13 | 1998-08-12 | Glaxo Group Ltd | Chemical compounds |
| US20060240105A1 (en) | 1998-11-02 | 2006-10-26 | Elan Corporation, Plc | Multiparticulate modified release composition |
| EP2020229A1 (en) | 1998-11-02 | 2009-02-04 | Elan Pharma International Limited | Multiparticulate modified release composition |
| DE19856167C1 (de) | 1998-12-05 | 2000-05-04 | Vetter & Co Apotheker | Nadelschutzanordnung für Spritzen, Karpulen und dergleichen Injektionsinstrumente |
| GB9929297D0 (en) | 1999-12-11 | 2000-02-02 | Glaxo Group Ltd | Process |
| WO2001054728A1 (fr) | 2000-01-28 | 2001-08-02 | Asahi Kasei Kabushiki Kaisha | NOUVEAUX REMEDES ET UTILISATION D'UN AGONISTE β3 |
| US6395762B1 (en) | 2000-07-17 | 2002-05-28 | American Home Products Corporation | Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists |
| US6525202B2 (en) | 2000-07-17 | 2003-02-25 | Wyeth | Cyclic amine phenyl beta-3 adrenergic receptor agonists |
| US6444685B1 (en) | 2000-07-17 | 2002-09-03 | Wyeth | N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists |
| US6451814B1 (en) | 2000-07-17 | 2002-09-17 | Wyeth | Heterocyclic β-3 adrenergic receptor agonists |
| US7709677B2 (en) | 2001-01-31 | 2010-05-04 | Glaxosmithkline Llc | Process of preparing arylethanoldiamines |
| US7034053B2 (en) | 2001-01-31 | 2006-04-25 | Smithkline Beecham Corporation | Phenethanolamine derivatives, compositions, and their use as agonists at atypical beta-adrenoreceptors |
| GB0102407D0 (en) * | 2001-01-31 | 2001-03-14 | Glaxo Group Ltd | Process |
| JP2004529902A (ja) | 2001-03-13 | 2004-09-30 | ペンウェスト ファーマシューティカルズ カンパニー | グルココルチコステロイドを含有する時間治療(chronotherapeutic)投与形態 |
| WO2003024483A1 (fr) | 2001-09-11 | 2003-03-27 | Fujisawa Pharmaceutical Co., Ltd. | Potentialisateur d'effets inhibiteurs sur la frequence des mictions et l'incontinence urinaire |
| TW200800953A (en) | 2002-10-30 | 2008-01-01 | Theravance Inc | Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine |
| EP1424079A1 (en) | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
| JP2007509896A (ja) | 2003-11-03 | 2007-04-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | β−3−アドレノセプターアゴニスト及びαアンタゴニスト及び/又は5−αレダクターゼインヒビターを含有する医薬組成物 |
| DE10352132A1 (de) | 2003-11-04 | 2005-06-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmazeutische Zusammensetzung aus einem Beta-3-Adrenozeptor-Agonisten und einem Alpha Agonisten |
| ES2329583T3 (es) | 2003-11-27 | 2009-11-27 | Develogen Aktiengesellschaft | Metodo para prevenir y tratar la diabetes con neurturina. |
| KR101071748B1 (ko) * | 2003-12-23 | 2011-10-11 | 아스텔라스세이야쿠 가부시키가이샤 | 아미노알콜 유도체 |
| US20050152974A1 (en) | 2003-12-31 | 2005-07-14 | Garth Boehm | Atomoxetine formulations |
| EP1550447A1 (en) | 2004-01-02 | 2005-07-06 | Schering Aktiengesellschaft | Menstrual cycle control and improvement of conception rates in females |
| WO2005077364A1 (ja) | 2004-02-18 | 2005-08-25 | Yamanouchi Pharmaceutical Co., Ltd. | ソリフェナシンの経皮投与製剤およびその経皮透過改善方法 |
| JP2008516909A (ja) | 2004-10-18 | 2008-05-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 前立腺及び下部泌尿生殖路の病気を治療するためのβ−3アゴニストの使用 |
| TW200716204A (en) | 2005-04-19 | 2007-05-01 | Smithkline Beecham Cork Ltd | Pharmaceutical composition |
| EP1769792A1 (de) | 2005-09-30 | 2007-04-04 | Boehringer Ingelheim Pharma GmbH & Co.KG | Verwendung eines beta-3-Adrenozeptor-Agonisten zur Behandlung von Nieren- und Blasenbeschwerden |
| ITMI20061581A1 (it) | 2006-08-04 | 2008-02-05 | Univ Bari | Ligandi del recettore beta-3 adrenergico e loro uso in terapia |
| EP1967202A1 (en) | 2007-03-05 | 2008-09-10 | AEterna Zentaris GmbH | Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity |
| CA2681749A1 (en) | 2007-03-29 | 2008-10-09 | Merck & Co., Inc. | Combination therapy for the treatment-of lower urinary tract symptoms |
| EP2064222B1 (en) | 2007-04-02 | 2014-05-07 | Theracos, Inc. | Benzylic glycoside derivatives and methods of use |
| GB0714790D0 (en) | 2007-07-30 | 2007-09-12 | Jagotec Ag | Improvements in or relating to organic compounds |
| SI2216021T1 (sl) | 2007-11-02 | 2013-01-31 | Astellas Pharma Inc. | Farmacevtski sestavek za zdravljenje prekomerno aktivnega sečnega mehurja |
| WO2009123870A1 (en) | 2008-04-04 | 2009-10-08 | Merck & Co., Inc. | Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists |
| PE20091825A1 (es) | 2008-04-04 | 2009-12-04 | Merck & Co Inc | Hidroximetil pirrolidinas como agonistas del receptor adrenergico beta 3 |
| EP2181707A1 (en) | 2008-11-04 | 2010-05-05 | Astellas Ireland Co., Ltd. | Combined use of an alpha-adrenergic receptor antagonist and an anti-muscarinic agent |
| US8778998B2 (en) | 2009-04-10 | 2014-07-15 | Auspex Pharmaceuticals, Inc. | Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor |
| US8828953B2 (en) | 2009-04-20 | 2014-09-09 | NaZura BioHealth, Inc. | Chemosensory receptor ligand-based therapies |
| US8618144B2 (en) | 2009-05-08 | 2013-12-31 | Merck Sharp & Dohme Corp | Pyrrolidine-derived beta 3 adrenergic receptor agonists |
| US8586760B2 (en) | 2009-06-15 | 2013-11-19 | Auspex Pharmaceuticals, Inc. | Aminothiazole modulators of beta-3-adrenoreceptor |
| EP2470021B1 (en) | 2009-08-27 | 2014-10-22 | Merck Sharp & Dohme Corp. | Novel pyrrolidine derived beta 3 adrenergic receptor agonists |
| IN2012DN00971A (pl) | 2009-08-27 | 2015-04-10 | Merck Sharp & Dohme | |
| MX2012004134A (es) | 2009-10-07 | 2012-05-08 | Merck Sharp & Dohme | Terapia de combinacion usando un agonista del receptor adrenergico beta 3 y un agente antimuscarinico. |
| HUE033199T2 (en) | 2009-12-15 | 2017-11-28 | Octeta Therapeutics Llc | PPAR-friendly thiazolidinediones and combinations for the treatment of neurodegenerative diseases |
| KR20120092714A (ko) | 2009-12-15 | 2012-08-21 | 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 | 비만 및 다른 대사성 질환의 치료를 위한 ppar 절약형 티아졸리딘디온 및 복합제 |
| EP2512471A1 (en) | 2009-12-15 | 2012-10-24 | Metabolic Solutions Development Company LLC | Ppar-sparing thiazolidinediones and combinations for the treatment of diabetes mellitus and other metabolic diseases |
| US8748433B2 (en) | 2010-04-30 | 2014-06-10 | Merck Sharp & Dohme Corp. | β3 adrenergic receptor agonists |
| KR101927068B1 (ko) | 2010-05-05 | 2018-12-10 | 베링거 인겔하임 인터내셔날 게엠베하 | 체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법 |
| WO2016004056A1 (en) | 2014-07-03 | 2016-01-07 | Velicept Therapeutics, Inc. | Pharmaceutical combinations |
| US9522129B2 (en) | 2010-08-03 | 2016-12-20 | Velicept Therapeutics, Inc. | Pharmaceutical Combination |
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| KR20130135239A (ko) * | 2010-08-03 | 2013-12-10 | 앨씨알엑스, 인크. | 과민성 방광 치료를 위한 베타-3 아드레날린 수용체 작용제 및 무스카린 수용체 길항제의 약학적 배합제 |
| WO2012154770A1 (en) | 2011-05-10 | 2012-11-15 | Theravida, Inc. | Combinations of tolterodine and salivary stimulants for the treatment of overactive bladder |
| KR20150020160A (ko) | 2012-02-09 | 2015-02-25 | 앨씨알엑스, 인크. | 과민성 방광의 치료를 위한 무스카린 수용체 길항제 및 베타―3 아드레날린 수용체 작용제의 조합물 |
| ES2394349B1 (es) | 2012-08-29 | 2013-11-04 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
| BR112015004244A2 (pt) | 2012-08-31 | 2017-07-04 | Astellas Pharma Inc | composição médica oralmente administrada |
| US20150306170A1 (en) | 2012-11-21 | 2015-10-29 | Ferring B.V. | Composition for immediate and extended release |
| EP2961730A2 (en) * | 2013-02-26 | 2016-01-06 | XenoPort, Inc. | Method of making 1-(acyloxy)-alkyl carbamate compounds |
| US10166183B2 (en) * | 2014-02-07 | 2019-01-01 | Auspex Pharmaceuticals, Inc. | Pharmaceutical formulations |
| AU2015358378A1 (en) * | 2014-12-03 | 2017-06-29 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
| IL258856B2 (en) | 2015-10-23 | 2024-07-01 | Velicept Therapeutics Inc | Solabegron zwitterion and uses thereof |
| WO2017210696A1 (en) | 2016-06-03 | 2017-12-07 | Velicept Therapeutics, Inc. | Dosing regimens for beta-3 adrenoceptor agonists and anti-muscarinic agents for the treatment and prevention of lower urinary tract symptoms and overactive bladder |
| WO2017210700A1 (en) | 2016-06-03 | 2017-12-07 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
| CN117529310A (zh) | 2021-03-31 | 2024-02-06 | B3Ar治疗股份有限公司 | 微粒化的索拉贝隆的组合物及其使用方法 |
-
2016
- 2016-10-24 IL IL258856A patent/IL258856B2/en unknown
- 2016-10-24 PT PT168584514T patent/PT3365321T/pt unknown
- 2016-10-24 ES ES16858451T patent/ES2967863T3/es active Active
- 2016-10-24 FI FIEP16858451.4T patent/FI3365321T3/fi active
- 2016-10-24 US US15/332,956 patent/US10065922B2/en active Active
- 2016-10-24 PL PL16858451.4T patent/PL3365321T3/pl unknown
- 2016-10-24 EP EP16858451.4A patent/EP3365321B1/en active Active
- 2016-10-24 IL IL310527A patent/IL310527A/en unknown
- 2016-10-24 DK DK16858451.4T patent/DK3365321T3/da active
- 2016-10-24 CN CN201680069478.7A patent/CN108290824B/zh active Active
- 2016-10-24 WO PCT/US2016/058516 patent/WO2017070689A2/en not_active Ceased
- 2016-10-24 CN CN202111549024.9A patent/CN114230477A/zh active Pending
- 2016-10-24 CA CA3001850A patent/CA3001850A1/en active Pending
-
2018
- 2018-06-26 US US16/018,945 patent/US10221126B2/en active Active
-
2019
- 2019-01-11 US US16/246,114 patent/US10844004B2/en active Active
-
2020
- 2020-10-22 US US17/077,446 patent/US11691944B2/en active Active
-
2023
- 2023-05-18 US US18/199,205 patent/US12435026B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2967863T3 (es) | 2024-05-06 |
| IL258856B2 (en) | 2024-07-01 |
| CN114230477A (zh) | 2022-03-25 |
| US20180370902A1 (en) | 2018-12-27 |
| IL310527A (en) | 2024-03-01 |
| US20170114005A1 (en) | 2017-04-27 |
| IL258856B1 (en) | 2024-03-01 |
| US11691944B2 (en) | 2023-07-04 |
| WO2017070689A3 (en) | 2017-07-20 |
| EP3365321A4 (en) | 2019-06-05 |
| US10065922B2 (en) | 2018-09-04 |
| CN108290824A (zh) | 2018-07-17 |
| EP3365321B1 (en) | 2023-12-13 |
| WO2017070689A2 (en) | 2017-04-27 |
| US12435026B2 (en) | 2025-10-07 |
| PT3365321T (pt) | 2024-01-12 |
| EP3365321A2 (en) | 2018-08-29 |
| US20190185414A1 (en) | 2019-06-20 |
| FI3365321T3 (fi) | 2024-01-02 |
| IL258856A (en) | 2018-06-28 |
| CA3001850A1 (en) | 2017-04-27 |
| HK1258038A1 (en) | 2019-11-01 |
| US20210317073A1 (en) | 2021-10-14 |
| US20240124391A1 (en) | 2024-04-18 |
| US10221126B2 (en) | 2019-03-05 |
| CN108290824B (zh) | 2022-03-11 |
| DK3365321T3 (da) | 2024-01-15 |
| US10844004B2 (en) | 2020-11-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL283321A (en) | Antibodies against muc16 and their uses | |
| IL258284A (en) | Anti-Lag 3 antibodies and their uses | |
| IL255577B (en) | Binding materials - tigit and their uses | |
| IL258248A (en) | Attraction Oligonucleotide Conjugates and Their Uses | |
| ZA201800536B (en) | Il-8-binding antibodies and uses thereof | |
| IL257263A (en) | Antibodies against angptl8 and their use | |
| IL253433A0 (en) | Binders - tnfrsf and their uses | |
| IL259367B (en) | Promoters and their uses | |
| IL254955B (en) | Anti-pacap antibodies and their uses | |
| SG10202008304TA (en) | Antibodies against ox40 and uses thereof | |
| IL247014A0 (en) | 6-heteroaryloxy and 6-aryloxy-quinoline-2-carboxamides and their use | |
| HUE044571T2 (hu) | Módosított ciklopentapeptidek és alkalmazásaik | |
| ZA201801549B (en) | Acetamide thienotriazoldiazepines and uses thereof | |
| SG11201708624YA (en) | Therapeutic antibodies and uses thereof | |
| PL3365321T3 (pl) | Jon obojnaczy solabegronu i jego zastosowania | |
| PT3292154T (pt) | Anticorpos anti-her3 humano e seus usos | |
| GB201503387D0 (en) | Anti-carbapenem antibodies and uses thereof | |
| ZA201801052B (en) | Combinations and uses thereof | |
| IL264473A (en) | GPR156 variants and their uses | |
| SG11201705748SA (en) | Anti-glycoprotein antibodies and uses thereof | |
| IL254241A0 (en) | Etv2 and its uses | |
| PL3307080T3 (pl) | Środek słodzący oraz jego zastosowanie | |
| GB2545167B (en) | Cloches and use thereof |