JP7562416B2 - 十二指腸ブルンナー腺由来の幹／前駆細胞ならびにそれらの単離および使用方法 - Google Patents

十二指腸ブルンナー腺由来の幹／前駆細胞ならびにそれらの単離および使用方法 Download PDF

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JP7562416B2
JP7562416B2 JP2020552401A JP2020552401A JP7562416B2 JP 7562416 B2 JP7562416 B2 JP 7562416B2 JP 2020552401 A JP2020552401 A JP 2020552401A JP 2020552401 A JP2020552401 A JP 2020552401A JP 7562416 B2 JP7562416 B2 JP 7562416B2
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cells
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stem
duodenum
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JP2021519585A5 (enExample
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カルピーノ，グイード
カーディナル，ヴィンチェンツォ
エム． リード，ローラ
アルヴァロ，ドメニコ
ガウディオ，エウジェニオ
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University of North Carolina at Chapel Hill
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    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/37—Digestive system
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C12N5/068—Stem cells; Progenitors
    • C—CHEMISTRY; METALLURGY
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    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10—Mechanical dissociation
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture

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  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020552401A 2018-03-29 2019-03-28 十二指腸ブルンナー腺由来の幹／前駆細胞ならびにそれらの単離および使用方法 Active JP7562416B2 (ja)

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JP2024044463A JP2024075687A (ja) 2018-03-29 2024-03-21 十二指腸ブルンナー腺由来の幹／前駆細胞ならびにそれらの単離および使用方法

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US201862650208P 2018-03-29 2018-03-29
US62/650,208 2018-03-29
PCT/US2019/024543 WO2019191402A1 (en) 2018-03-29 2019-03-28 Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them

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JP2024044463A Pending JP2024075687A (ja) 2018-03-29 2024-03-21 十二指腸ブルンナー腺由来の幹／前駆細胞ならびにそれらの単離および使用方法

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US (1) US20190300849A1 (enExample)
EP (1) EP3781181A4 (enExample)
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KR (1) KR20200140836A (enExample)
CN (1) CN112272698A (enExample)
AR (1) AR115304A1 (enExample)
AU (1) AU2019242887A1 (enExample)
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Families Citing this family (10)

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SG10202104575WA (en) 2016-11-04 2021-06-29 Childrens Hospital Med Ct Liver organoid compositions and methods of making and using same
CA3106634A1 (en) 2018-07-26 2020-01-30 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
CN112823012A (zh) 2018-09-12 2021-05-18 儿童医院医学中心 用于产生造血干细胞及其衍生物的类器官组合物
WO2020160371A1 (en) 2019-02-01 2020-08-06 The University Of Hong Kong Innervated organoid compositions and methods of making same
CA3141807A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
US12534709B2 (en) 2019-05-31 2026-01-27 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
KR102322635B1 (ko) * 2021-06-11 2021-11-05 인제대학교 산학협력단 말초신경양 미세조직 제조방법 및 이의 용도
AU2022304681A1 (en) * 2021-07-02 2024-01-25 Children’S Hospital Medical Center Structurally complete organoids
WO2023171702A1 (ja) * 2022-03-08 2023-09-14 慶應義塾 オルガノイドの製造方法
KR20250118284A (ko) * 2024-01-29 2025-08-06 (의) 삼성의료재단 중간엽 줄기세포 유래 췌도 오가노이드의 제조방법

Citations (4)

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US20050256077A1 (en) 2004-03-30 2005-11-17 Henning Susan J Gastrointestinal stem cells and uses thereof
US20070128584A1 (en) 2005-12-01 2007-06-07 Illani Atwater Method for isolation of cells
US20160084824A1 (en) 2008-04-23 2016-03-24 Alfagene Bioscience, Inc. Drug discovery methods involving a preclnical, in vitro isolated gastrointestinal epithelial stem cell-like progenitor cell system
JP2016513466A (ja) 2013-03-13 2016-05-16 ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 胆管壁内への幹細胞移植によって膵臓及び肝臓の疾患を治療する方法

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US20070026520A1 (en) * 2005-07-29 2007-02-01 Kelly James H Novel cells, compositions, and methods
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US20050256077A1 (en) 2004-03-30 2005-11-17 Henning Susan J Gastrointestinal stem cells and uses thereof
US20070128584A1 (en) 2005-12-01 2007-06-07 Illani Atwater Method for isolation of cells
US20160084824A1 (en) 2008-04-23 2016-03-24 Alfagene Bioscience, Inc. Drug discovery methods involving a preclnical, in vitro isolated gastrointestinal epithelial stem cell-like progenitor cell system
JP2016513466A (ja) 2013-03-13 2016-05-16 ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 胆管壁内への幹細胞移植によって膵臓及び肝臓の疾患を治療する方法

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BR112020019773A2 (pt) 2021-02-17
CA3112650A1 (en) 2019-10-03
IL277552B1 (en) 2024-04-01
IL311366B1 (en) 2025-01-01
SG11202009428YA (en) 2020-10-29
MX2020010223A (es) 2021-01-15
KR20200140836A (ko) 2020-12-16
IL277552B2 (en) 2024-08-01
EP3781181A1 (en) 2021-02-24
JP2021519585A (ja) 2021-08-12
IL311366B2 (en) 2025-05-01
JP2024075687A (ja) 2024-06-04
EP3781181A4 (en) 2021-12-29
IL277552A (en) 2020-11-30
US20190300849A1 (en) 2019-10-03
AU2019242887A1 (en) 2020-11-12
PH12020551584A1 (en) 2021-09-13
CN112272698A (zh) 2021-01-26
IL311366A (en) 2024-05-01
WO2019191402A1 (en) 2019-10-03
AR115304A1 (es) 2020-12-23
TW202002997A (zh) 2020-01-16

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