CN112272698A - 来自十二指肠布鲁纳氏腺的干/祖细胞及其分离和使用方法 - Google Patents

来自十二指肠布鲁纳氏腺的干/祖细胞及其分离和使用方法 Download PDF

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Publication number
CN112272698A
CN112272698A CN201980033560.8A CN201980033560A CN112272698A CN 112272698 A CN112272698 A CN 112272698A CN 201980033560 A CN201980033560 A CN 201980033560A CN 112272698 A CN112272698 A CN 112272698A
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cells
cell
isolated
medium
bgsc
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圭多·卡尔皮诺
温琴佐·卡尔迪纳莱
洛拉·M·里德
多梅尼科·阿尔瓦罗
欧金尼奥·高迪奥
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Sapienza University of Rome
University of North Carolina at Chapel Hill
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Sapienza University of Rome
University of North Carolina at Chapel Hill
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C12N5/068—Stem cells; Progenitors
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture

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  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201980033560.8A 2018-03-29 2019-03-28 来自十二指肠布鲁纳氏腺的干/祖细胞及其分离和使用方法 Pending CN112272698A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862650208P 2018-03-29 2018-03-29
US62/650,208 2018-03-29
PCT/US2019/024543 WO2019191402A1 (en) 2018-03-29 2019-03-28 Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them

Publications (1)

Publication Number Publication Date
CN112272698A true CN112272698A (zh) 2021-01-26

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US (1) US20190300849A1 (enExample)
EP (1) EP3781181A4 (enExample)
JP (2) JP7562416B2 (enExample)
KR (1) KR20200140836A (enExample)
CN (1) CN112272698A (enExample)
AR (1) AR115304A1 (enExample)
AU (1) AU2019242887A1 (enExample)
BR (1) BR112020019773A2 (enExample)
CA (1) CA3112650A1 (enExample)
IL (2) IL311366B2 (enExample)
MX (1) MX2020010223A (enExample)
PH (1) PH12020551584A1 (enExample)
SG (1) SG11202009428YA (enExample)
TW (1) TW202002997A (enExample)
WO (1) WO2019191402A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10202104575WA (en) 2016-11-04 2021-06-29 Childrens Hospital Med Ct Liver organoid compositions and methods of making and using same
CA3106634A1 (en) 2018-07-26 2020-01-30 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
CN112823012A (zh) 2018-09-12 2021-05-18 儿童医院医学中心 用于产生造血干细胞及其衍生物的类器官组合物
WO2020160371A1 (en) 2019-02-01 2020-08-06 The University Of Hong Kong Innervated organoid compositions and methods of making same
CA3141807A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
US12534709B2 (en) 2019-05-31 2026-01-27 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
KR102322635B1 (ko) * 2021-06-11 2021-11-05 인제대학교 산학협력단 말초신경양 미세조직 제조방법 및 이의 용도
AU2022304681A1 (en) * 2021-07-02 2024-01-25 Children’S Hospital Medical Center Structurally complete organoids
WO2023171702A1 (ja) * 2022-03-08 2023-09-14 慶應義塾 オルガノイドの製造方法
KR20250118284A (ko) * 2024-01-29 2025-08-06 (의) 삼성의료재단 중간엽 줄기세포 유래 췌도 오가노이드의 제조방법

Citations (4)

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US20150132846A1 (en) * 2008-11-04 2015-05-14 Viacyte, Inc. Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
CN105264065A (zh) * 2013-03-13 2016-01-20 北卡罗来纳大学教堂山分校 通过将干细胞移植到胆管壁来治疗胰腺和肝脏病症的方法
US20160084824A1 (en) * 2008-04-23 2016-03-24 Alfagene Bioscience, Inc. Drug discovery methods involving a preclnical, in vitro isolated gastrointestinal epithelial stem cell-like progenitor cell system
CN105456292A (zh) * 2009-10-30 2016-04-06 北卡罗来纳大学教堂山分校 来自肝外胆管树的专能干细胞及其分离方法

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WO2002057430A2 (en) * 2001-01-20 2002-07-25 Cardion Ag Pluripotent adult stem cells derived from regenerative tissue
US20050256077A1 (en) 2004-03-30 2005-11-17 Henning Susan J Gastrointestinal stem cells and uses thereof
US20070026520A1 (en) * 2005-07-29 2007-02-01 Kelly James H Novel cells, compositions, and methods
US20070128584A1 (en) 2005-12-01 2007-06-07 Illani Atwater Method for isolation of cells
CN101668848B (zh) * 2007-04-26 2014-10-22 雷蒙特亚特特拉维夫大学有限公司 来自口腔粘膜的多能自体干细胞和使用方法
EP2326336B1 (en) * 2008-07-30 2015-05-13 Mesynthes Limited Tissue scaffolds derived from forestomach extracellular matrix
US8367316B2 (en) * 2009-05-01 2013-02-05 Alfagene Bioscience, Inc. Human gastrointestinal stem cell-derived primary intestinal epithelial cell system and methods of use thereof
WO2012070014A2 (en) * 2010-11-26 2012-05-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Identification of novel cell surface markers for pancreatic progenitor cells and definite endodermal cells
CN105087479A (zh) * 2015-08-21 2015-11-25 深圳爱生再生医学科技有限公司 干细胞无血清培养基及干细胞的培养方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160084824A1 (en) * 2008-04-23 2016-03-24 Alfagene Bioscience, Inc. Drug discovery methods involving a preclnical, in vitro isolated gastrointestinal epithelial stem cell-like progenitor cell system
US20150132846A1 (en) * 2008-11-04 2015-05-14 Viacyte, Inc. Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
CN105456292A (zh) * 2009-10-30 2016-04-06 北卡罗来纳大学教堂山分校 来自肝外胆管树的专能干细胞及其分离方法
CN105264065A (zh) * 2013-03-13 2016-01-20 北卡罗来纳大学教堂山分校 通过将干细胞移植到胆管壁来治疗胰腺和肝脏病症的方法

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BR112020019773A2 (pt) 2021-02-17
CA3112650A1 (en) 2019-10-03
IL277552B1 (en) 2024-04-01
IL311366B1 (en) 2025-01-01
SG11202009428YA (en) 2020-10-29
MX2020010223A (es) 2021-01-15
KR20200140836A (ko) 2020-12-16
IL277552B2 (en) 2024-08-01
JP7562416B2 (ja) 2024-10-07
EP3781181A1 (en) 2021-02-24
JP2021519585A (ja) 2021-08-12
IL311366B2 (en) 2025-05-01
JP2024075687A (ja) 2024-06-04
EP3781181A4 (en) 2021-12-29
IL277552A (en) 2020-11-30
US20190300849A1 (en) 2019-10-03
AU2019242887A1 (en) 2020-11-12
PH12020551584A1 (en) 2021-09-13
IL311366A (en) 2024-05-01
WO2019191402A1 (en) 2019-10-03
AR115304A1 (es) 2020-12-23
TW202002997A (zh) 2020-01-16

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