JP7515254B2 - Ｂ細胞のゲノム編集のための組成物及び方法 - Google Patents

Ｂ細胞のゲノム編集のための組成物及び方法 Download PDF

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JP7515254B2
JP7515254B2 JP2019502554A JP2019502554A JP7515254B2 JP 7515254 B2 JP7515254 B2 JP 7515254B2 JP 2019502554 A JP2019502554 A JP 2019502554A JP 2019502554 A JP2019502554 A JP 2019502554A JP 7515254 B2 JP7515254 B2 JP 7515254B2
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cells
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isolated
nuclease
dna
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JP2019510513A (ja
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マイケル・ゴールドバーグ
ヴェラ・グレイナー
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デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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JP2019502554A 2015-04-03 2017-04-04 Ｂ細胞のゲノム編集のための組成物及び方法 Active JP7515254B2 (ja)

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JP2022109722A JP7463442B2 (ja) 2015-04-03 2022-07-07 Ｂ細胞のゲノム編集のための組成物及び方法
JP2024052302A JP2024071612A (ja) 2015-04-03 2024-03-27 Ｂ細胞のゲノム編集のための組成物及び方法

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US201562142882P 2015-04-03 2015-04-03
PCT/US2016/025920 WO2016161446A1 (en) 2015-04-03 2016-04-04 Composition and methods of genome editing of b-cells
USPCT/US2016/025920 2016-04-04
US15/161,213 US20160289637A1 (en) 2015-04-03 2016-05-21 Composition and methods of genome editing of b-cells
US15/161,213 2016-05-21
PCT/US2017/026011 WO2017176806A1 (en) 2015-04-03 2017-04-04 Composition and methods of genome editing of b cells

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AU (5) AU2016243052C1 (enExample)
CA (2) CA2981077A1 (enExample)
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