JP7475099B2 - チアミン誘導体を含む移植片対宿主疾患予防又は治療用薬学的組成物 - Google Patents
チアミン誘導体を含む移植片対宿主疾患予防又は治療用薬学的組成物 Download PDFInfo
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Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Description
Claims (8)
- 下記化学式1で表示されるチアミン(Thiamine)誘導体及びそれらの薬剤学的に許容可能な塩(salts)からなる群から選ばれる1種以上の化合物を含むことを特徴とする、移植片対宿主疾患(Graft Versus Host Disease;GVHD)予防又は治療用薬学的組成物:
(化学式1)
- チアミン(Thiamine)誘導体及びそれらの薬剤学的に許容可能な塩(salts)からなる群から選ばれる1種以上の化合物を含む移植片対宿主疾患(Graft Versus Host Disease;GVHD)予防又は治療用薬学的組成物であって、
チアミン誘導体は、フルスルチアミン(fursultiamine)又はアリチアミン(allithiamine)であることを特徴とする、移植片対宿主疾患予防又は治療用薬学的組成物。 - チアミン誘導体は、フルスルチアミン(fursultiamine)である、請求項1又は2に記載の移植片対宿主疾患予防又は治療用薬学的組成物。
- 移植片対宿主疾患は、放射線照射後に造血幹細胞移植を進行した癌患者に発生するものである、請求項1又は2に記載の移植片対宿主疾患予防又は治療用薬学的組成物。
- 下記化学式1で表示されるチアミン(Thiamine)誘導体及びそれらの薬剤学的に許容可能な塩(salts)からなる群から選ばれる1種以上の化合物を含むことを特徴とする、移植片対宿主疾患(Graft Versus Host Disease;GVHD)改善用食品組成物:
(化学式1)
- チアミン(Thiamine)誘導体及びそれらの薬剤学的に許容可能な塩(salts)からなる群から選ばれる1種以上の化合物を含む移植片対宿主疾患(Graft Versus Host Disease;GVHD)改善用食品組成物であって、
チアミン誘導体は、フルスルチアミン(fursultiamine)又はアリチアミン(allithiamine)であることを特徴とする、移植片対宿主疾患改善用食品組成物。 - チアミン誘導体は、フルスルチアミン(fursultiamine)である、請求項5又は6に記載移植片対宿主疾患(Graft Versus Host Disease;GVHD)改善用食品組成物。
- 移植片対宿主疾患は、放射線照射後に造血幹細胞移植を進行した癌患者に発生するものである、請求項5又は6に記載の移植片対宿主疾患改善用食品組成物。
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KR1020200120568A KR102636847B1 (ko) | 2020-09-18 | 2020-09-18 | 티아민 유도체를 포함하는 이식편대숙주질환 예방 또는 치료용 약학적 조성물 |
PCT/KR2021/012578 WO2022060079A1 (ko) | 2020-09-18 | 2021-09-15 | 티아민 유도체를 포함하는 이식편대숙주질환 예방 또는 치료용 약학적 조성물 |
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