JP7466218B2 - 高純度間葉系幹細胞 - Google Patents

高純度間葉系幹細胞 Download PDF

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JP7466218B2
JP7466218B2 JP2021570631A JP2021570631A JP7466218B2 JP 7466218 B2 JP7466218 B2 JP 7466218B2 JP 2021570631 A JP2021570631 A JP 2021570631A JP 2021570631 A JP2021570631 A JP 2021570631A JP 7466218 B2 JP7466218 B2 JP 7466218B2
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有未 松崎
隆史 陶山
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Purec Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/10—Production naturally occurring
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021570631A 2020-01-16 2020-04-06 高純度間葉系幹細胞 Active JP7466218B2 (ja)

Priority Applications (1)

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JP2024050204A JP7792151B2 (ja) 2020-01-16 2024-03-26 高純度間葉系幹細胞

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PCT/JP2020/002197 WO2021144995A1 (ja) 2020-01-16 2020-01-16 高純度間葉系幹細胞
JPPCT/JP2020/002197 2020-01-16
PCT/JP2020/016228 WO2021145002A1 (ja) 2020-01-16 2020-04-06 高純度間葉系幹細胞

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JP7466218B2 true JP7466218B2 (ja) 2024-04-12

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US (1) US20230002735A1 (https=)
EP (1) EP4053266A4 (https=)
JP (2) JP7466218B2 (https=)
KR (1) KR20220084078A (https=)
CN (1) CN114846134B (https=)
AU (1) AU2020423706B2 (https=)
CA (1) CA3163517C (https=)
IL (1) IL293724A (https=)
WO (2) WO2021144995A1 (https=)

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WO2022177032A1 (ja) * 2021-02-19 2022-08-25 ＰｕＲＥＣ株式会社 骨疾患治療用医薬組成物
AU2024354962A1 (en) 2023-10-02 2026-03-12 National University Corporation Tokai National Higher Education And Research System Method for managing quality of stem cells by image analysis using ai
TW202529782A (zh) * 2023-10-05 2025-08-01 日商ＰｕＲＥＣ股份有限公司 含有高純度間葉系幹細胞之用以治療以及／或是預防粒線體疾病之組成物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009031678A1 (ja) 2007-09-06 2009-03-12 Keio University ヒト間葉系幹細胞濃縮方法
JP2012500214A (ja) 2008-08-14 2012-01-05 オシリス セラピューティクス，インコーポレイテッド 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
WO2016017795A1 (ja) 2014-08-01 2016-02-04 有未 伊谷 ヒト間葉系幹細胞の品質評価方法、及び、そのためのモノクローナル抗体

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
JPS6025329B2 (ja) 1980-07-25 1985-06-18 株式会社日立製作所 鋼管移送騒音防止装置
DE102006043625B4 (de) * 2006-09-12 2012-02-23 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verfahren zur Isolierung und/oder Identifizierung von mesenchymalen Stammzellen (MSC)
JP6463029B2 (ja) 2013-08-02 2019-01-30 有未 伊谷 ヒト間葉系幹細胞を特異的に認識するモノクローナル抗体並びにこれを用いたヒト間葉系幹細胞の分離及び／または品質評価を行う方法
KR20160017795A (ko) 2014-08-05 2016-02-17 삼성디스플레이 주식회사 박막 트랜지스터 기판, 이의 제조 방법, 및 박막 트랜지스터 기판을 포함하는 표시 장치
EP3336177A1 (fr) * 2016-12-16 2018-06-20 Stem Cell Vet Therapeutics Procede de culture, d'isolement et d'enrichissement de cellules souches mesenchymateuses clonogeniques, a fort rendement, en vue d'une utilisation therapeutique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009031678A1 (ja) 2007-09-06 2009-03-12 Keio University ヒト間葉系幹細胞濃縮方法
JP2012500214A (ja) 2008-08-14 2012-01-05 オシリス セラピューティクス，インコーポレイテッド 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
WO2016017795A1 (ja) 2014-08-01 2016-02-04 有未 伊谷 ヒト間葉系幹細胞の品質評価方法、及び、そのためのモノクローナル抗体

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PuREC 島根大学発バイオベンチャー, Research & Development, 研究シーズとそれを基に目指す製品・サービス，[オンライン], インターネット: <URL: https://www.purec.jp/ research_and_development/>, 公開日: 2017.05.21 (当該公開日はインターネットアーカイブ <URL: https://archive.org/web/web.php>による)，[検索日: 2020.06.19]
STEM CELL REPORTS，2013年08月06日，Vol. 1，pp. 152-165
STEM CELLS INTERNATIONAL，2018年，Vol. 2018, Article ID 3038565，pp. 1-16

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Publication number Publication date
CN114846134A (zh) 2022-08-02
WO2021145002A8 (ja) 2022-06-30
WO2021145002A1 (ja) 2021-07-22
JPWO2021145002A1 (https=) 2021-07-22
CN114846134B (zh) 2024-10-29
CA3163517A1 (en) 2021-07-22
AU2020423706A1 (en) 2022-06-23
IL293724A (en) 2022-08-01
US20230002735A1 (en) 2023-01-05
JP2024089675A (ja) 2024-07-03
WO2021144995A1 (ja) 2021-07-22
EP4053266A1 (en) 2022-09-07
CA3163517C (en) 2025-05-13
EP4053266A4 (en) 2023-01-11
JP7792151B2 (ja) 2025-12-25
KR20220084078A (ko) 2022-06-21
AU2020423706B2 (en) 2024-10-24

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