AU2020423706B2 - High-purity mesenchymal stem cells - Google Patents

High-purity mesenchymal stem cells Download PDF

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Publication number
AU2020423706B2
AU2020423706B2 AU2020423706A AU2020423706A AU2020423706B2 AU 2020423706 B2 AU2020423706 B2 AU 2020423706B2 AU 2020423706 A AU2020423706 A AU 2020423706A AU 2020423706 A AU2020423706 A AU 2020423706A AU 2020423706 B2 AU2020423706 B2 AU 2020423706B2
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Australia
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cell
cell population
less
lngfr
mesenchymal stem
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AU2020423706A
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AU2020423706A1 (en
Inventor
Yumi Matsuzaki
Takashi Suyama
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Purec Co Ltd
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Purec Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/10—Production naturally occurring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2020423706A 2020-01-16 2020-04-06 High-purity mesenchymal stem cells Active AU2020423706B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/JP2020/002197 WO2021144995A1 (ja) 2020-01-16 2020-01-16 高純度間葉系幹細胞
AUPCT/JP2020/002197 2020-01-16
PCT/JP2020/016228 WO2021145002A1 (ja) 2020-01-16 2020-04-06 高純度間葉系幹細胞

Publications (2)

Publication Number Publication Date
AU2020423706A1 AU2020423706A1 (en) 2022-06-23
AU2020423706B2 true AU2020423706B2 (en) 2024-10-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020423706A Active AU2020423706B2 (en) 2020-01-16 2020-04-06 High-purity mesenchymal stem cells

Country Status (9)

Country Link
US (1) US20230002735A1 (https=)
EP (1) EP4053266A4 (https=)
JP (2) JP7466218B2 (https=)
KR (1) KR20220084078A (https=)
CN (1) CN114846134B (https=)
AU (1) AU2020423706B2 (https=)
CA (1) CA3163517C (https=)
IL (1) IL293724A (https=)
WO (2) WO2021144995A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022177032A1 (ja) * 2021-02-19 2022-08-25 ＰｕＲＥＣ株式会社 骨疾患治療用医薬組成物
AU2024354962A1 (en) 2023-10-02 2026-03-12 National University Corporation Tokai National Higher Education And Research System Method for managing quality of stem cells by image analysis using ai
TW202529782A (zh) * 2023-10-05 2025-08-01 日商ＰｕＲＥＣ股份有限公司 含有高純度間葉系幹細胞之用以治療以及／或是預防粒線體疾病之組成物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110053183A1 (en) * 2007-09-06 2011-03-03 Yumi Matsuzaki Method of concentrating human mesenchymal stem cells
AU2015297347B2 (en) * 2014-08-01 2021-05-27 PuREC Co., Ltd Method for evaluating quality of human mesenchymal stem cell, and monoclonal antibody for use in said method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6025329B2 (ja) 1980-07-25 1985-06-18 株式会社日立製作所 鋼管移送騒音防止装置
DE102006043625B4 (de) * 2006-09-12 2012-02-23 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verfahren zur Isolierung und/oder Identifizierung von mesenchymalen Stammzellen (MSC)
EP3124601A1 (en) * 2008-08-14 2017-02-01 Mesoblast International Sàrl Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions
JP6463029B2 (ja) 2013-08-02 2019-01-30 有未 伊谷 ヒト間葉系幹細胞を特異的に認識するモノクローナル抗体並びにこれを用いたヒト間葉系幹細胞の分離及び／または品質評価を行う方法
KR20160017795A (ko) 2014-08-05 2016-02-17 삼성디스플레이 주식회사 박막 트랜지스터 기판, 이의 제조 방법, 및 박막 트랜지스터 기판을 포함하는 표시 장치
EP3336177A1 (fr) * 2016-12-16 2018-06-20 Stem Cell Vet Therapeutics Procede de culture, d'isolement et d'enrichissement de cellules souches mesenchymateuses clonogeniques, a fort rendement, en vue d'une utilisation therapeutique

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110053183A1 (en) * 2007-09-06 2011-03-03 Yumi Matsuzaki Method of concentrating human mesenchymal stem cells
AU2015297347B2 (en) * 2014-08-01 2021-05-27 PuREC Co., Ltd Method for evaluating quality of human mesenchymal stem cell, and monoclonal antibody for use in said method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MABUCHI Y. ET AL.: "LNGFR+THY-I+VCAM-Ihi+ cells reveal functionally distinct subpopulations in mesenchymal stem cells", STEM CELL REPORTS, vol. 1, 6 August 2013 (2013-08-06), pages 152 - 165, XP055391281, DOI: 10.1016/j.stemcr.2013.06.001 *
RESEARCH & DEVELOPMENT:2017.Research Seeds and Products Based on Those Seeds/Overview of Services. Development of Identification and Separation Method of High-quality MSC in Human Bone Marrow and(2)Research Results Obtained to Date. *

Also Published As

Publication number Publication date
CN114846134A (zh) 2022-08-02
WO2021145002A8 (ja) 2022-06-30
WO2021145002A1 (ja) 2021-07-22
JPWO2021145002A1 (https=) 2021-07-22
CN114846134B (zh) 2024-10-29
JP7466218B2 (ja) 2024-04-12
CA3163517A1 (en) 2021-07-22
AU2020423706A1 (en) 2022-06-23
IL293724A (en) 2022-08-01
US20230002735A1 (en) 2023-01-05
JP2024089675A (ja) 2024-07-03
WO2021144995A1 (ja) 2021-07-22
EP4053266A1 (en) 2022-09-07
CA3163517C (en) 2025-05-13
EP4053266A4 (en) 2023-01-11
JP7792151B2 (ja) 2025-12-25
KR20220084078A (ko) 2022-06-21

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