JP7433051B2 - Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 - Google Patents
Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 Download PDFInfo
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- JP7433051B2 JP7433051B2 JP2019571410A JP2019571410A JP7433051B2 JP 7433051 B2 JP7433051 B2 JP 7433051B2 JP 2019571410 A JP2019571410 A JP 2019571410A JP 2019571410 A JP2019571410 A JP 2019571410A JP 7433051 B2 JP7433051 B2 JP 7433051B2
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K38/19—Cytokines; Lymphokines; Interferons
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- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023211159A JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
| JP2025155111A JP2026001033A (ja) | 2017-06-19 | 2025-09-18 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762521957P | 2017-06-19 | 2017-06-19 | |
| US62/521,957 | 2017-06-19 | ||
| US201862679687P | 2018-06-01 | 2018-06-01 | |
| US62/679,687 | 2018-06-01 | ||
| PCT/IB2018/000760 WO2018234862A1 (en) | 2017-06-19 | 2018-06-19 | Uses and methods for il-2 superagonists, agonists, and fusions thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023211159A Division JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020524174A JP2020524174A (ja) | 2020-08-13 |
| JP2020524174A5 JP2020524174A5 (https=) | 2021-07-29 |
| JP7433051B2 true JP7433051B2 (ja) | 2024-02-19 |
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ID=64737001
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571410A Active JP7433051B2 (ja) | 2017-06-19 | 2018-06-19 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
| JP2023211159A Active JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
| JP2025155111A Pending JP2026001033A (ja) | 2017-06-19 | 2025-09-18 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023211159A Active JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
| JP2025155111A Pending JP2026001033A (ja) | 2017-06-19 | 2025-09-18 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11542312B2 (https=) |
| EP (1) | EP3641814A4 (https=) |
| JP (3) | JP7433051B2 (https=) |
| CN (1) | CN111201035A (https=) |
| AU (2) | AU2018287317B2 (https=) |
| CA (2) | CA3291498A1 (https=) |
| WO (1) | WO2018234862A1 (https=) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014236207B2 (en) | 2013-03-14 | 2019-05-23 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| WO2015164815A1 (en) | 2014-04-24 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists, partial agonists and antagonists of interleukin-2 |
| KR20250081944A (ko) | 2014-09-24 | 2025-06-05 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| EP4155411A1 (en) | 2016-02-23 | 2023-03-29 | Salk Institute for Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| EP3532082A4 (en) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES |
| BR112019018915A2 (pt) | 2017-03-15 | 2020-04-14 | Pandion Therapeutics Inc | imunotolerância direcionada |
| JP2020521452A (ja) | 2017-05-24 | 2020-07-27 | パンディオン・セラピューティクス・インコーポレイテッド | 標的化免疫寛容 |
| AU2018287317B2 (en) | 2017-06-19 | 2024-06-20 | Medicenna Therapeutics Inc. | Uses and methods for IL-2 superagonists, agonists, and fusions thereof |
| US20200299349A1 (en) | 2017-11-21 | 2020-09-24 | The Board Of Trustees Of The Leland Stanford Junior University | Partial agonists of interleukin-2 |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| EP3768698B1 (en) * | 2018-03-19 | 2025-02-12 | MultiVir Inc. | Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer |
| MX2020010499A (es) | 2018-04-09 | 2020-10-28 | Salk Inst For Biological Studi | Composiciones de adenovirus oncoliticas con propiedades aumentadas de replicacion. |
| MX2021000801A (es) * | 2018-07-24 | 2021-04-12 | BioNTech SE | Agonistas de il2. |
| HUE067601T2 (hu) | 2018-11-14 | 2024-10-28 | Regeneron Pharma | PD-1 inhibitorok intraléziós beadása a bõrrák kezelésére |
| KR20210113265A (ko) * | 2019-01-07 | 2021-09-15 | 인히브릭스, 인크. | 변형된 il-2 폴리펩타이드를 포함하는 폴리펩타이드 및 이의 용도 |
| US11529402B2 (en) | 2019-01-14 | 2022-12-20 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
| MA55084A (fr) * | 2019-02-28 | 2022-01-05 | Regeneron Pharma | Administration d'inhibiteurs de pd-1 pour le traitement du cancer de la peau |
| AU2020252119B2 (en) * | 2019-03-29 | 2025-09-04 | Centre National De La Recherche Scientifique - Cnrs | Interleukin-2 variants with modified biological activity |
| WO2020236875A1 (en) | 2019-05-20 | 2020-11-26 | Pandion Therapeutics, Inc. | Madcam targeted immunotolerance |
| AU2020287373B2 (en) * | 2019-06-05 | 2026-01-29 | Asher Biotherapeutics, Inc. | Fusions of mutant interleukin-2 polypeptides with antigen binding molecules for modulating immune cell function |
| CN110256583B (zh) * | 2019-07-11 | 2022-05-20 | 中国科学院生物物理研究所 | 一种il-2突变体与抗体的融合蛋白及其应用 |
| AU2020315800A1 (en) | 2019-07-19 | 2022-03-03 | Seneca Therapeutics, Inc. | Second generation seneca valley virus oncolytic therapy: compositions and methods thereof |
| EP4013777A4 (en) * | 2019-08-15 | 2024-01-17 | Cytimm Therapeutics, Inc. | MODIFIED INTERLEUKIN 2 (IL-2) POLYPEPTIDES, CONJUGATES AND USES THEREOF |
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| US20230080403A1 (en) | 2023-03-16 |
| US12338269B2 (en) | 2025-06-24 |
| EP3641814A1 (en) | 2020-04-29 |
| JP2026001033A (ja) | 2026-01-06 |
| CA3291498A1 (en) | 2026-03-02 |
| AU2024219911A1 (en) | 2024-10-10 |
| CA3067909A1 (en) | 2018-12-27 |
| JP2024028986A (ja) | 2024-03-05 |
| US20190062395A1 (en) | 2019-02-28 |
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