JP7402805B2 - ベイロネラ（Ｖｅｉｌｌｏｎｅｌｌａ）の細菌を使用して癌及び免疫障害を処置するための組成物及び方法 - Google Patents

ベイロネラ（Ｖｅｉｌｌｏｎｅｌｌａ）の細菌を使用して癌及び免疫障害を処置するための組成物及び方法 Download PDF

Info

Publication number
JP7402805B2
JP7402805B2 JP2020542296A JP2020542296A JP7402805B2 JP 7402805 B2 JP7402805 B2 JP 7402805B2 JP 2020542296 A JP2020542296 A JP 2020542296A JP 2020542296 A JP2020542296 A JP 2020542296A JP 7402805 B2 JP7402805 B2 JP 7402805B2
Authority
JP
Japan
Prior art keywords
pieces
veillonella
pharmaceutical composition
bacteria
bacterium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2020542296A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021512133A (ja
JP2021512133A5 (enExample
Inventor
グッドマン，ブライアン
ボーズ，バウンダウナ
ダビット，クリストファー，ジェイエイチ
シゾバ，マリア
カールトン，ソフィア，エム．アール．
イタノ，アンドレア
ポニチテラ，ホリー
コーマック，テイラー，エー．
ラマニ，クリティカ
Original Assignee
エヴェロ バイオサイエンシズ，インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エヴェロ バイオサイエンシズ，インコーポレーテッド filed Critical エヴェロ バイオサイエンシズ，インコーポレーテッド
Publication of JP2021512133A publication Critical patent/JP2021512133A/ja
Publication of JP2021512133A5 publication Critical patent/JP2021512133A5/ja
Application granted granted Critical
Publication of JP7402805B2 publication Critical patent/JP7402805B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Sustainable Development (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
JP2020542296A 2018-02-06 2019-02-06 ベイロネラ（Ｖｅｉｌｌｏｎｅｌｌａ）の細菌を使用して癌及び免疫障害を処置するための組成物及び方法 Active JP7402805B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862626789P 2018-02-06 2018-02-06
US62/626,789 2018-02-06
US201862666944P 2018-05-04 2018-05-04
US62/666,944 2018-05-04
US201862703269P 2018-07-25 2018-07-25
US62/703,269 2018-07-25
PCT/US2019/016763 WO2019157003A1 (en) 2018-02-06 2019-02-06 Compositions and methods for treating cancer and immune disorders using veillonella bacteria

Publications (3)

Publication Number Publication Date
JP2021512133A JP2021512133A (ja) 2021-05-13
JP2021512133A5 JP2021512133A5 (enExample) 2022-02-15
JP7402805B2 true JP7402805B2 (ja) 2023-12-21

Family

ID=65767281

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542296A Active JP7402805B2 (ja) 2018-02-06 2019-02-06 ベイロネラ（Ｖｅｉｌｌｏｎｅｌｌａ）の細菌を使用して癌及び免疫障害を処置するための組成物及び方法

Country Status (13)

Country Link
US (2) US11090341B2 (enExample)
EP (1) EP3749340A1 (enExample)
JP (1) JP7402805B2 (enExample)
KR (1) KR20200118100A (enExample)
CN (1) CN112074283A (enExample)
AU (1) AU2019217526A1 (enExample)
BR (1) BR112020015639A2 (enExample)
CA (1) CA3090166A1 (enExample)
CO (1) CO2020010956A2 (enExample)
MX (1) MX2020008244A (enExample)
SA (1) SA520412543B1 (enExample)
TW (1) TW201945015A (enExample)
WO (1) WO2019157003A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022520999A (ja) * 2019-02-22 2022-04-04 エヴェロ バイオサイエンシズ，インコーポレーテッド 細菌の膜調製物

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017100420A1 (en) * 2015-12-08 2017-06-15 Mayo Foundation For Medical Education And Research Biomarkers for predicting clostridium difficile infection treatment outcome
IL265109B2 (en) 2016-09-13 2024-05-01 Allergan Inc Stabilized non-protein clostridial toxin compositions
WO2021142279A1 (en) * 2020-01-10 2021-07-15 Evelo Biosciences, Inc. Compositions and methods of treatment using veillonella parvula
CN115551486A (zh) * 2020-04-17 2022-12-30 伊夫罗生物科学公司 具有改善的崩解谱的固体剂型
CN114796264A (zh) * 2021-01-27 2022-07-29 北京北工大科技园有限公司 金络合物在制备治疗新型冠状病毒肺炎的药物中的应用
WO2022051494A1 (en) * 2020-09-03 2022-03-10 Evelo Biosciences, Inc. Compositions and methods for resolution of inflammation
TW202233214A (zh) 2020-11-06 2022-09-01 美商艾弗洛生物科技股份有限公司 使用小韋榮氏球菌細菌誘導免疫效應
JP2024501481A (ja) 2020-12-14 2024-01-12 エヴェロ バイオサイエンシズ，インコーポレーテッド 細胞外小胞調製物
WO2022191183A1 (ja) * 2021-03-08 2022-09-15 学校法人順天堂 炎症抑制作用を有する組成物及び改善剤
TW202304415A (zh) * 2021-04-08 2023-02-01 美商艾弗洛生物科技股份有限公司 含有細菌的藥物製劑
WO2023062422A1 (en) * 2021-10-11 2023-04-20 Vastu Vihar Biotech Private Limited An anti-inflammatory composition and a method of obtaining the same
KR102859962B1 (ko) * 2021-10-20 2025-09-18 주식회사 고바이오랩 항암 활성을 갖는 베일로넬라 파르불라 균주를 이용한 암의 완화, 예방 또는 치료용 조성물
WO2023114300A1 (en) 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Fournierella massiliensis bacteria extracellular vesicle preparations
WO2023114295A1 (en) 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Veillonella parvula bacteria extracellular vesicle preparations
CN114146098A (zh) * 2021-12-31 2022-03-08 中山大学 Veillonella atypica在制备预防和/或治疗结直肠癌药物中的应用
WO2023146843A1 (en) 2022-01-25 2023-08-03 Evelo Biosciences, Inc. Extracellular vesicle compositions and methods of use
WO2023234587A1 (ko) * 2022-05-30 2023-12-07 한국생명공학연구원 베일로넬라 세미날리스 균주, 그의 유래의 배양액 및 그의 항염증 용도
KR102861997B1 (ko) * 2022-05-30 2025-09-22 한국생명공학연구원 베일로넬라 세미날리스 균주, 그의 유래의 배양액 및 그의 항염증 용도
CN116355785A (zh) * 2022-09-29 2023-06-30 南京市儿童医院 一株小韦荣氏球菌及其在制备诊断和治疗口腔鳞状细胞癌产品中的应用
CN115990260B (zh) * 2022-12-09 2025-07-22 中国药科大学 一种用于抗肿瘤的联用组合药物
EP4658287A1 (en) * 2023-01-30 2025-12-10 MRM Health N.V. Microbial compositions for treating joint inflammation
TWI859033B (zh) * 2023-12-18 2024-10-11 安益藥業股份有限公司 一種診斷犬科動物胰臟炎的方法與試劑組與一種使用醯基肉鹼作為診斷犬科動物胰臟炎之用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016141454A1 (en) 2015-03-12 2016-09-15 The University Of British Columbia Bacterial compositions and methods of use thereof
JP2020533290A (ja) 2017-09-08 2020-11-19 エヴェロ バイオサイエンシズ，インコーポレーテッド 細菌の細胞外小胞
JP2022538765A (ja) 2019-06-11 2022-09-06 エヴェロ バイオサイエンシズ，インコーポレーテッド 処理された微生物細胞外小胞

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57139090A (en) * 1981-02-19 1982-08-27 Toyama Chem Co Ltd Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same
JPH04330016A (ja) * 1991-05-01 1992-11-18 Rikagaku Kenkyusho 過酸化脂質低下剤
US6368586B1 (en) 1996-01-26 2002-04-09 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
EP0991761B1 (en) * 1997-08-21 2008-01-16 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Novel mutants of gram negative mucosal bacteria and application thereof in vaccines
GB0130123D0 (en) 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
WO2004069156A2 (en) * 2003-01-30 2004-08-19 The Regents Of The University Of California Inactivated probiotic bacteria and methods of use thereof
CA2571805C (en) * 2006-10-27 2018-05-01 Harold David Gunn Tissue targeted antigenic activation of the immune response to cancers
US8906668B2 (en) * 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
AU2014239883B2 (en) 2013-03-14 2019-01-17 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
WO2015038731A1 (en) * 2013-09-12 2015-03-19 The Johns Hopkins University Biofilm formation to define risk for colon cancer
WO2015095241A2 (en) * 2013-12-16 2015-06-25 Seres Health, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
WO2016040074A1 (en) * 2014-09-11 2016-03-17 Drexel University Maximizing production of hydrogen from waste materials by active removal of hydrogen
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
SE1550189A1 (en) * 2015-02-19 2016-08-20 Achim Biotherapeutics Ab Therapeutic and prophylactic composition produced by microbiota
KR101734653B1 (ko) * 2015-06-23 2017-05-11 서울대학교산학협력단 아미노글리코시드계 항생제 및 프로바이오틱스를 포함하는 아프타 구내염 예방 또는 치료용 약학적 조성물

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016141454A1 (en) 2015-03-12 2016-09-15 The University Of British Columbia Bacterial compositions and methods of use thereof
JP2020533290A (ja) 2017-09-08 2020-11-19 エヴェロ バイオサイエンシズ，インコーポレーテッド 細菌の細胞外小胞
JP2022538765A (ja) 2019-06-11 2022-09-06 エヴェロ バイオサイエンシズ，インコーポレーテッド 処理された微生物細胞外小胞

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Veillonella parvula strain ATCC 17745 16S ribosomal RNA gene, partial sequence，GenBank: AY995769.1，2005年04月25日，https://www.ncbi.nlm.nih.gov/nuccore/AY995769
Veillonella sp. oral clone VeillB2 16S ribosomal RNA gene, partial sequence，GenBank: AY995751.1，2005年05月02日，https://www.ncbi.nlm.nih.gov/nuccore/AY995751.1?report=genbank&to=1459
Veillonella tobetsuensis gene for 16S ribosomal RNA, partial sequence，GenBank: AB679109.1，2013年04月13日，https://www.ncbi.nlm.nih.gov/nuccore/AB679109

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022520999A (ja) * 2019-02-22 2022-04-04 エヴェロ バイオサイエンシズ，インコーポレーテッド 細菌の膜調製物

Also Published As

Publication number Publication date
MX2020008244A (es) 2020-09-25
US20210330718A1 (en) 2021-10-28
KR20200118100A (ko) 2020-10-14
JP2021512133A (ja) 2021-05-13
BR112020015639A2 (pt) 2021-03-30
CN112074283A (zh) 2020-12-11
SA520412543B1 (ar) 2023-12-11
EP3749340A1 (en) 2020-12-16
CO2020010956A2 (es) 2020-10-30
CA3090166A1 (en) 2019-08-15
WO2019157003A1 (en) 2019-08-15
WO2019157003A9 (en) 2020-03-19
US20190350987A1 (en) 2019-11-21
US11090341B2 (en) 2021-08-17
TW201945015A (zh) 2019-12-01
AU2019217526A1 (en) 2020-08-13

Similar Documents

Publication Publication Date Title
US10702561B2 (en) Pharmaceutical compositions comprising a Blautia strain
US11090341B2 (en) Compositions and methods for treating cancer and immune disorders using Veillonella bacteria
US20220211773A1 (en) Compositions and methods for treating immune disorders using immune modulating lactococcus bacteria strains
TWI840334B (zh) 源自普雷沃菌(prevotella)之胞外囊泡
TWI814739B (zh) 細菌胞外囊泡
US20210052669A1 (en) Compositions and methods for treating immune disorders using lachnospiraceae bacteria
WO2020252144A1 (en) Secreted microbial extracellular vesicles
WO2019178487A2 (en) Compositions and methods for treating disease using klebsiella quasipneumoniae subsp. similipneumoniae
WO2019178490A1 (en) Compositions and methods for treating cancer and inflammation using klebsiella oxytoca
WO2019178494A1 (en) Compositions and methods for treating cancer and inflammation using tyzzerella nexilis
TW202140050A (zh) 使用小韋榮氏球菌進行治療的組成物及方法

Legal Events

Date Code Title Description
RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7426

Effective date: 20210324

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20210324

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220204

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220204

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20221124

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20221129

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230224

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230523

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230823

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20231121

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20231211

R150 Certificate of patent or registration of utility model

Ref document number: 7402805

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150