JPS57139090A - Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same - Google Patents
Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the sameInfo
- Publication number
- JPS57139090A JPS57139090A JP56022278A JP2227881A JPS57139090A JP S57139090 A JPS57139090 A JP S57139090A JP 56022278 A JP56022278 A JP 56022278A JP 2227881 A JP2227881 A JP 2227881A JP S57139090 A JPS57139090 A JP S57139090A
- Authority
- JP
- Japan
- Prior art keywords
- carcinostatic
- substance
- reactions
- veillonella
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:A carcinostatic substance TV-110. Appearance: Whitish gray W light brown powder. Melting point: Indifinite, begins to decompose at about 110°C and remarkably decomposes at 200°C or above. Elementary analysis: C, 37W41%; H, 4W6%; N, 4W7%. Solubility: Insoluble in methanol, ethanol, etc. Color reactions: Positive to the Molisch, phenol-sulfuric acid, anthrone-sulfuric reactions, etc.
USE: A carcinostatic agent, capable of inhibiting the multiplication of murine Ehrlich ascitic cancers, Ehrilich tuberous carcinoma and sarcoma 180 cancerous cells, and having the immunological activating actions with very low toxicity.
PROCESS: A microorganism, e.g. Veillonella alcalescens TF-V strain, (FERM-P No.5876), of the genus Veillonella is cultivated under anaerobic conditions, and a hydrophilic organic solvent is added to the supernatant liquid. The formed precipitate is then separated and purified to give the aimed carcinostatic substance TV-110.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56022278A JPS57139090A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56022278A JPS57139090A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57139090A true JPS57139090A (en) | 1982-08-27 |
JPH0242478B2 JPH0242478B2 (en) | 1990-09-21 |
Family
ID=12078288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56022278A Granted JPS57139090A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57139090A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019157003A1 (en) * | 2018-02-06 | 2019-08-15 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer and immune disorders using veillonella bacteria |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5622279A (en) * | 1979-07-31 | 1981-03-02 | Fujitsu Ltd | Buffer managing system |
-
1981
- 1981-02-19 JP JP56022278A patent/JPS57139090A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5622279A (en) * | 1979-07-31 | 1981-03-02 | Fujitsu Ltd | Buffer managing system |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019157003A1 (en) * | 2018-02-06 | 2019-08-15 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer and immune disorders using veillonella bacteria |
US11090341B2 (en) | 2018-02-06 | 2021-08-17 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer and immune disorders using Veillonella bacteria |
Also Published As
Publication number | Publication date |
---|---|
JPH0242478B2 (en) | 1990-09-21 |
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