JPS57139090A - Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same - Google Patents

Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same

Info

Publication number
JPS57139090A
JPS57139090A JP56022278A JP2227881A JPS57139090A JP S57139090 A JPS57139090 A JP S57139090A JP 56022278 A JP56022278 A JP 56022278A JP 2227881 A JP2227881 A JP 2227881A JP S57139090 A JPS57139090 A JP S57139090A
Authority
JP
Japan
Prior art keywords
carcinostatic
substance
reactions
veillonella
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56022278A
Other languages
Japanese (ja)
Other versions
JPH0242478B2 (en
Inventor
Kenzo Tamai
Isamu Saikawa
Takashi Yasuda
Shohachi Murakami
Toyoo Maeda
Maki Miyahara
Hisatsugu Tsuda
Masatoshi Sugita
Yoshiko Yamamoto
Takashi Minami
Hidetada Mikami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP56022278A priority Critical patent/JPS57139090A/en
Publication of JPS57139090A publication Critical patent/JPS57139090A/en
Publication of JPH0242478B2 publication Critical patent/JPH0242478B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:A carcinostatic substance TV-110. Appearance: Whitish gray W light brown powder. Melting point: Indifinite, begins to decompose at about 110°C and remarkably decomposes at 200°C or above. Elementary analysis: C, 37W41%; H, 4W6%; N, 4W7%. Solubility: Insoluble in methanol, ethanol, etc. Color reactions: Positive to the Molisch, phenol-sulfuric acid, anthrone-sulfuric reactions, etc.
USE: A carcinostatic agent, capable of inhibiting the multiplication of murine Ehrlich ascitic cancers, Ehrilich tuberous carcinoma and sarcoma 180 cancerous cells, and having the immunological activating actions with very low toxicity.
PROCESS: A microorganism, e.g. Veillonella alcalescens TF-V strain, (FERM-P No.5876), of the genus Veillonella is cultivated under anaerobic conditions, and a hydrophilic organic solvent is added to the supernatant liquid. The formed precipitate is then separated and purified to give the aimed carcinostatic substance TV-110.
COPYRIGHT: (C)1982,JPO&Japio
JP56022278A 1981-02-19 1981-02-19 Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same Granted JPS57139090A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56022278A JPS57139090A (en) 1981-02-19 1981-02-19 Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56022278A JPS57139090A (en) 1981-02-19 1981-02-19 Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same

Publications (2)

Publication Number Publication Date
JPS57139090A true JPS57139090A (en) 1982-08-27
JPH0242478B2 JPH0242478B2 (en) 1990-09-21

Family

ID=12078288

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56022278A Granted JPS57139090A (en) 1981-02-19 1981-02-19 Carcinostatic substance tv-110, its preparation and carcinostatic agent containing the same

Country Status (1)

Country Link
JP (1) JPS57139090A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019157003A1 (en) * 2018-02-06 2019-08-15 Evelo Biosciences, Inc. Compositions and methods for treating cancer and immune disorders using veillonella bacteria

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5622279A (en) * 1979-07-31 1981-03-02 Fujitsu Ltd Buffer managing system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5622279A (en) * 1979-07-31 1981-03-02 Fujitsu Ltd Buffer managing system

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019157003A1 (en) * 2018-02-06 2019-08-15 Evelo Biosciences, Inc. Compositions and methods for treating cancer and immune disorders using veillonella bacteria
US11090341B2 (en) 2018-02-06 2021-08-17 Evelo Biosciences, Inc. Compositions and methods for treating cancer and immune disorders using Veillonella bacteria

Also Published As

Publication number Publication date
JPH0242478B2 (en) 1990-09-21

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