JP7330896B2 - 抗ｔｓｌｐ抗体による喘息治療 - Google Patents

抗ｔｓｌｐ抗体による喘息治療 Download PDF

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Publication number
JP7330896B2
JP7330896B2 JP2019555854A JP2019555854A JP7330896B2 JP 7330896 B2 JP7330896 B2 JP 7330896B2 JP 2019555854 A JP2019555854 A JP 2019555854A JP 2019555854 A JP2019555854 A JP 2019555854A JP 7330896 B2 JP7330896 B2 JP 7330896B2
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antibody
seq
amino acid
acid sequence
tslp
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JP2020516647A (ja
JP2020516647A5 (https=
JPWO2018191479A5 (https=
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ジェーン アール． パーネス，
ジャネット グリフィス，
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Amgen Inc
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Amgen Inc
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Priority to JP2023080295A priority Critical patent/JP2023099233A/ja
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Priority to JP2024127900A priority patent/JP2024150751A/ja
Priority to JP2025147176A priority patent/JP2025170430A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2019555854A 2017-04-12 2018-04-12 抗ｔｓｌｐ抗体による喘息治療 Active JP7330896B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2023080295A JP2023099233A (ja) 2017-04-12 2023-05-15 抗ｔｓｌｐ抗体による喘息治療
JP2024127900A JP2024150751A (ja) 2017-04-12 2024-08-02 抗ｔｓｌｐ抗体による喘息治療
JP2025147176A JP2025170430A (ja) 2017-04-12 2025-09-04 抗ｔｓｌｐ抗体による喘息治療

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762484864P 2017-04-12 2017-04-12
US62/484,864 2017-04-12
US201762553575P 2017-09-01 2017-09-01
US201762553477P 2017-09-01 2017-09-01
US62/553,575 2017-09-01
US62/553,477 2017-09-01
PCT/US2018/027271 WO2018191479A1 (en) 2017-04-12 2018-04-12 Treatment of asthma with anti-tslp antibody

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023080295A Division JP2023099233A (ja) 2017-04-12 2023-05-15 抗ｔｓｌｐ抗体による喘息治療

Publications (4)

Publication Number Publication Date
JP2020516647A JP2020516647A (ja) 2020-06-11
JP2020516647A5 JP2020516647A5 (https=) 2022-11-22
JPWO2018191479A5 JPWO2018191479A5 (https=) 2022-11-22
JP7330896B2 true JP7330896B2 (ja) 2023-08-22

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JP2019555854A Active JP7330896B2 (ja) 2017-04-12 2018-04-12 抗ｔｓｌｐ抗体による喘息治療
JP2023080295A Withdrawn JP2023099233A (ja) 2017-04-12 2023-05-15 抗ｔｓｌｐ抗体による喘息治療
JP2024127900A Pending JP2024150751A (ja) 2017-04-12 2024-08-02 抗ｔｓｌｐ抗体による喘息治療
JP2025147176A Pending JP2025170430A (ja) 2017-04-12 2025-09-04 抗ｔｓｌｐ抗体による喘息治療

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JP2023080295A Withdrawn JP2023099233A (ja) 2017-04-12 2023-05-15 抗ｔｓｌｐ抗体による喘息治療
JP2024127900A Pending JP2024150751A (ja) 2017-04-12 2024-08-02 抗ｔｓｌｐ抗体による喘息治療
JP2025147176A Pending JP2025170430A (ja) 2017-04-12 2025-09-04 抗ｔｓｌｐ抗体による喘息治療

Country Status (22)

Country Link
US (3) US10828365B2 (https=)
EP (1) EP3609917A1 (https=)
JP (4) JP7330896B2 (https=)
KR (2) KR20240070727A (https=)
CN (1) CN110573525A (https=)
AU (2) AU2018253118B2 (https=)
BR (1) BR112019021482A2 (https=)
CA (1) CA3059364A1 (https=)
CL (1) CL2019002897A1 (https=)
CO (1) CO2019011462A2 (https=)
IL (1) IL269791B (https=)
JO (1) JOP20190243B1 (https=)
MX (1) MX2019012158A (https=)
MY (1) MY207509A (https=)
PE (1) PE20200484A1 (https=)
PH (1) PH12019502331A1 (https=)
SG (1) SG11201909322VA (https=)
TN (1) TN2019000289A1 (https=)
TW (2) TW202523688A (https=)
UA (1) UA130334C2 (https=)
UY (1) UY37676A (https=)
WO (1) WO2018191479A1 (https=)

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JP2023099233A (ja) * 2017-04-12 2023-07-11 アムジェン インコーポレイテッド 抗ｔｓｌｐ抗体による喘息治療

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EP3981788A4 (en) * 2019-06-04 2023-03-22 Jiangsu Hengrui Medicine Co., Ltd. ANTIBODY CAPABLE OF BINDING THYMIC STROMAL LYMPHOPOIETIN AND ITS USE
JP7597784B2 (ja) * 2019-07-11 2024-12-10 タヴォテック バイオセラピューティクス （ホン コン） リミテッド 胸腺間質性リンパ球新生因子（ｔｓｌｐ）受容体シグナル伝達に干渉する薬剤
KR102809618B1 (ko) * 2019-09-04 2025-05-16 바이오션, 인코포레이티드 Tslp에 결합하는 항체 및 이의 용도
LT4051708T (lt) * 2019-10-28 2025-04-10 Medimmune Limited Užkrūčio liaukos stromos limfopoetiną (tslp) surišančių antikūnų sausų miltelių pavidalo vaisto formos ir jų panaudojimo būdai
CN114887053B (zh) * 2019-11-29 2026-04-24 康诺亚生物医药科技（成都）有限公司 一种tslp相关病症治疗剂的开发和应用
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EP4103235A1 (en) * 2020-02-13 2022-12-21 Amgen Inc. Formulations of human anti-tslp antibodies and methods of treating inflammatory disease
US20230073888A1 (en) * 2020-02-13 2023-03-09 Amgen Inc. Treatment of atopic dermatitis with anti-tslp antibody
EP4106811A1 (en) * 2020-02-18 2022-12-28 Amgen Inc. Formulations of human anti-tslp antibodies and methods of using the same
CN113388035B (zh) * 2020-03-13 2026-02-27 迈威(上海)生物科技股份有限公司 特异性针对人tslp的抗体及其应用
WO2022117079A1 (zh) * 2020-12-03 2022-06-09 江苏恒瑞医药股份有限公司 结合胸腺基质淋巴细胞生成素的抗体及其应用
CN113501878B (zh) * 2021-02-03 2022-12-02 北京智仁美博生物科技有限公司 针对人tslp的多种抗体及其用途
CN114853888B (zh) * 2021-02-05 2023-11-03 上海洛启生物医药技术有限公司 抗tslp纳米抗体及其应用
KR20230152062A (ko) * 2021-03-03 2023-11-02 치아타이 티안큉 파마수티컬 그룹 주식회사 항tslp 항체를 포함하는 의약 조성물
PH12023552762A1 (en) * 2021-04-19 2024-04-15 Medimmune Ltd An anti-tslp fab with improved stability
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KR20230175245A (ko) 2021-04-23 2023-12-29 암젠 인크 변형된 항-tslp 항체
CN113683694B (zh) * 2021-09-03 2022-05-13 江苏荃信生物医药股份有限公司 一种抗人tslp单克隆抗体及其应用
CN117106084B (zh) * 2021-12-02 2024-03-22 北京东方百泰生物科技股份有限公司 一种抗tslp的单克隆抗体、其抗原结合片段及其应用
CN117327176A (zh) * 2022-06-24 2024-01-02 南京融捷康生物科技有限公司 一种抗tslp的单域抗体及其用途
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TW202523697A (zh) * 2023-08-25 2025-06-16 美商普羅特歐拉吉克適美國公司 抗ｔｓｌｐ抗體構築體及其用途
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JP2023099233A (ja) * 2017-04-12 2023-07-11 アムジェン インコーポレイテッド 抗ｔｓｌｐ抗体による喘息治療

Also Published As

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UY37676A (es) 2018-10-31
TW202523688A (zh) 2025-06-16
IL269791A (en) 2019-11-28
JP2025170430A (ja) 2025-11-18
US20180296669A1 (en) 2018-10-18
JP2020516647A (ja) 2020-06-11
EP3609917A1 (en) 2020-02-19
SG11201909322VA (en) 2019-11-28
TWI856945B (zh) 2024-10-01
WO2018191479A1 (en) 2018-10-18
PH12019502331A1 (en) 2020-09-28
US20250032608A1 (en) 2025-01-30
KR102666879B1 (ko) 2024-05-23
MY207509A (en) 2025-02-28
US10828365B2 (en) 2020-11-10
AU2018253118B2 (en) 2025-04-10
MX2019012158A (es) 2019-12-16
PE20200484A1 (es) 2020-03-03
UA130334C2 (uk) 2026-01-28
US20210052726A1 (en) 2021-02-25
CO2019011462A2 (es) 2019-10-31
KR20190140956A (ko) 2019-12-20
JOP20190243B1 (ar) 2024-12-22
JOP20190243A1 (ar) 2019-10-13
BR112019021482A2 (pt) 2020-05-12
CN110573525A (zh) 2019-12-13
AU2025204735A1 (en) 2025-07-17
TN2019000289A1 (en) 2021-05-07
JP2024150751A (ja) 2024-10-23
CA3059364A1 (en) 2018-10-18
TW201838652A (zh) 2018-11-01
CL2019002897A1 (es) 2020-03-06
KR20240070727A (ko) 2024-05-21
AU2018253118A1 (en) 2019-10-24
JP2023099233A (ja) 2023-07-11
IL269791B (en) 2022-07-01

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