JP7315472B2 - 炎症症状で使用するための抗ｉｌ－１ｒ３抗体 - Google Patents

炎症症状で使用するための抗ｉｌ－１ｒ３抗体 Download PDF

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JP7315472B2
JP7315472B2 JP2019561281A JP2019561281A JP7315472B2 JP 7315472 B2 JP7315472 B2 JP 7315472B2 JP 2019561281 A JP2019561281 A JP 2019561281A JP 2019561281 A JP2019561281 A JP 2019561281A JP 7315472 B2 JP7315472 B2 JP 7315472B2
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JP2020519590A (ja
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フィッシャー、シュテファン
ベックマン、カルステン
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サノフィ・バイオテクノロジー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019561281A 2017-05-08 2018-05-08 炎症症状で使用するための抗ｉｌ－１ｒ３抗体 Active JP7315472B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023114162A JP7605916B2 (ja) 2017-05-08 2023-07-12 炎症症状で使用するための抗ｉｌ－１ｒ３抗体
JP2024216380A JP7825695B2 (ja) 2017-05-08 2024-12-11 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17169953.1A EP3401332A1 (en) 2017-05-08 2017-05-08 Anti-il-1r3 antibodies for use in inflammatory conditions
EP17169953.1 2017-05-08
PCT/EP2018/061846 WO2018206565A1 (en) 2017-05-08 2018-05-08 Anti-il-1r3 antibodies for use in inflammatory conditions

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JP2023114162A Division JP7605916B2 (ja) 2017-05-08 2023-07-12 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

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JP2020519590A JP2020519590A (ja) 2020-07-02
JP7315472B2 true JP7315472B2 (ja) 2023-07-26

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JP2019561281A Active JP7315472B2 (ja) 2017-05-08 2018-05-08 炎症症状で使用するための抗ｉｌ－１ｒ３抗体
JP2023114162A Active JP7605916B2 (ja) 2017-05-08 2023-07-12 炎症症状で使用するための抗ｉｌ－１ｒ３抗体
JP2024216380A Active JP7825695B2 (ja) 2017-05-08 2024-12-11 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

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JP2023114162A Active JP7605916B2 (ja) 2017-05-08 2023-07-12 炎症症状で使用するための抗ｉｌ－１ｒ３抗体
JP2024216380A Active JP7825695B2 (ja) 2017-05-08 2024-12-11 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

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US (2) US11639392B2 (enExample)
EP (2) EP3401332A1 (enExample)
JP (3) JP7315472B2 (enExample)
CN (1) CN110831670A (enExample)
AU (2) AU2018267092B2 (enExample)
CA (1) CA3062424A1 (enExample)
WO (1) WO2018206565A1 (enExample)

Cited By (1)

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JP2023134618A (ja) * 2017-05-08 2023-09-27 サノフィ・バイオテクノロジー 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

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CN108026172B (zh) 2015-06-26 2022-04-29 赛诺菲生物技术公司 单克隆抗il-1racp抗体
EP3241845A1 (en) 2016-05-06 2017-11-08 MAB Discovery GmbH Humanized anti-il-1r3 antibodies
EP3592384B1 (en) * 2017-03-09 2025-07-02 MAB Discovery GmbH Antibodies specifically binding to human il-1r7
WO2018231827A1 (en) 2017-06-12 2018-12-20 Bluefin Biomedicine, Inc. Anti-il1rap antibodies and antibody drug conjugates
WO2019057792A1 (en) * 2017-09-19 2019-03-28 Mab Discovery Gmbh CD40 ANTIBODY AGONISTS
TW202021618A (zh) 2018-08-17 2020-06-16 美商２３與我有限公司 抗ｉｌ１ｒａｐ抗體及其使用方法
MX2021007589A (es) * 2018-12-21 2021-12-10 23Andme Inc Anticuerpos anti il-36 y procedimientos de uso de estos.
US20220298234A1 (en) * 2019-05-13 2022-09-22 The Johns Hopkins University Macrophage diversity in regenerative, fibrotic biomaterial environments
KR20230077722A (ko) * 2020-08-10 2023-06-01 지브이20 테라퓨틱스 엘엘씨 Igsf8을 표적화하여 자가면역 질환 및 암을 치료하기 위한 조성물 및 방법
CN112358539A (zh) * 2020-11-16 2021-02-12 桂林医学院附属医院 一种小鼠截短IL-36γ蛋白及其制备方法
MX2023013714A (es) 2021-05-21 2024-01-16 Leo Pharma As Anticuerpos anti-proteina accesoria del receptor de interleucina 1 (il-1).
US12054552B2 (en) * 2022-09-21 2024-08-06 Sanofi Biotechnology Humanized anti-IL-1R3 antibody and methods of use
WO2026003765A1 (en) 2024-06-25 2026-01-02 Kiniksa Pharmaceuticals, Gmbh Formulations of anti-interleukin 1 receptor 1 antibodies
WO2026006472A2 (en) 2024-06-25 2026-01-02 Kiniksa Pharmaceuticals, Gmbh Compositions of il-1r1 antibodies and methods of producing and using the same
WO2026022232A1 (en) 2024-07-24 2026-01-29 Almirall, S.A. Il-1rap inhibitor for treating or preventing hidradenitis suppurativa

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Cited By (2)

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JP2023134618A (ja) * 2017-05-08 2023-09-27 サノフィ・バイオテクノロジー 炎症症状で使用するための抗ｉｌ－１ｒ３抗体
JP7605916B2 (ja) 2017-05-08 2024-12-24 サノフィ・バイオテクノロジー 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

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JP2025038044A (ja) 2025-03-18
CA3062424A1 (en) 2018-11-15
US20230383000A1 (en) 2023-11-30
US20200140559A1 (en) 2020-05-07
AU2018267092A1 (en) 2019-11-14
EP3621693B1 (en) 2026-06-24
CN110831670A (zh) 2020-02-21
JP7825695B2 (ja) 2026-03-06
JP7605916B2 (ja) 2024-12-24
JP2020519590A (ja) 2020-07-02
JP2023134618A (ja) 2023-09-27
WO2018206565A1 (en) 2018-11-15
AU2018267092B2 (en) 2024-02-08
US11639392B2 (en) 2023-05-02
WO2018206565A9 (en) 2019-12-26
EP3401332A1 (en) 2018-11-14
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