AU2018267092B2 - Anti-IL-1R3 antibodies for use in inflammatory conditions - Google Patents

Anti-IL-1R3 antibodies for use in inflammatory conditions Download PDF

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Publication number
AU2018267092B2
AU2018267092B2 AU2018267092A AU2018267092A AU2018267092B2 AU 2018267092 B2 AU2018267092 B2 AU 2018267092B2 AU 2018267092 A AU2018267092 A AU 2018267092A AU 2018267092 A AU2018267092 A AU 2018267092A AU 2018267092 B2 AU2018267092 B2 AU 2018267092B2
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AU2018267092A1 (en
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Karsten Beckmann
Stephan Fischer
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Sanofi Biotechnology SAS
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Sanofi Biotechnology SAS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2018267092A 2017-05-08 2018-05-08 Anti-IL-1R3 antibodies for use in inflammatory conditions Active AU2018267092B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024202910A AU2024202910A1 (en) 2017-05-08 2024-05-02 Anti-IL-1R3 antibodies for use in inflammatory conditions

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17169953.1 2017-05-08
EP17169953.1A EP3401332A1 (en) 2017-05-08 2017-05-08 Anti-il-1r3 antibodies for use in inflammatory conditions
PCT/EP2018/061846 WO2018206565A1 (en) 2017-05-08 2018-05-08 Anti-il-1r3 antibodies for use in inflammatory conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2024202910A Division AU2024202910A1 (en) 2017-05-08 2024-05-02 Anti-IL-1R3 antibodies for use in inflammatory conditions

Publications (2)

Publication Number Publication Date
AU2018267092A1 AU2018267092A1 (en) 2019-11-14
AU2018267092B2 true AU2018267092B2 (en) 2024-02-08

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2018267092A Active AU2018267092B2 (en) 2017-05-08 2018-05-08 Anti-IL-1R3 antibodies for use in inflammatory conditions
AU2024202910A Pending AU2024202910A1 (en) 2017-05-08 2024-05-02 Anti-IL-1R3 antibodies for use in inflammatory conditions

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2024202910A Pending AU2024202910A1 (en) 2017-05-08 2024-05-02 Anti-IL-1R3 antibodies for use in inflammatory conditions

Country Status (7)

Country Link
US (2) US11639392B2 (enExample)
EP (2) EP3401332A1 (enExample)
JP (3) JP7315472B2 (enExample)
CN (1) CN110831670A (enExample)
AU (2) AU2018267092B2 (enExample)
CA (1) CA3062424A1 (enExample)
WO (1) WO2018206565A1 (enExample)

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EP3241845A1 (en) 2016-05-06 2017-11-08 MAB Discovery GmbH Humanized anti-il-1r3 antibodies
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EP3401332A1 (en) * 2017-05-08 2018-11-14 MAB Discovery GmbH Anti-il-1r3 antibodies for use in inflammatory conditions
CN118994394A (zh) 2017-06-12 2024-11-22 蓝鳍生物医药公司 抗-il1rap抗体和抗体药物缀合物
CN111225924B (zh) 2017-09-19 2023-10-10 Mab发现股份有限公司 激动性cd40抗体
TW202021618A (zh) * 2018-08-17 2020-06-16 美商２３與我有限公司 抗ｉｌ１ｒａｐ抗體及其使用方法
AU2019405782A1 (en) * 2018-12-21 2021-06-17 23Andme, Inc. Anti-IL-36 antibodies and methods of use thereof
US20220298234A1 (en) * 2019-05-13 2022-09-22 The Johns Hopkins University Macrophage diversity in regenerative, fibrotic biomaterial environments
US20220411517A1 (en) 2021-05-21 2022-12-29 Leo Pharma A/S IL-1 Receptor Accessory Protein Inhibitors and Uses Thereof
WO2024062074A1 (en) * 2022-09-21 2024-03-28 Sanofi Biotechnology Humanized anti-il-1r3 antibody and methods of use

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WO2016020502A1 (en) * 2014-08-06 2016-02-11 Cantargia Ab Novel antibodies and uses thereof

Also Published As

Publication number Publication date
CA3062424A1 (en) 2018-11-15
AU2024202910A1 (en) 2024-05-23
WO2018206565A9 (en) 2019-12-26
WO2018206565A1 (en) 2018-11-15
US20230383000A1 (en) 2023-11-30
EP3401332A1 (en) 2018-11-14
AU2018267092A1 (en) 2019-11-14
JP7315472B2 (ja) 2023-07-26
CN110831670A (zh) 2020-02-21
JP7605916B2 (ja) 2024-12-24
US11639392B2 (en) 2023-05-02
JP2025038044A (ja) 2025-03-18
EP3621693A1 (en) 2020-03-18
JP2020519590A (ja) 2020-07-02
JP2023134618A (ja) 2023-09-27
US20200140559A1 (en) 2020-05-07

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Owner name: SANOFI BIOTECHNOLOGY SAS

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FGA Letters patent sealed or granted (standard patent)