JP7257399B2 - 多嚢胞性卵巣症候群に罹患している女性患者における胚着床率を高める方法 - Google Patents

多嚢胞性卵巣症候群に罹患している女性患者における胚着床率を高める方法 Download PDF

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JP7257399B2
JP7257399B2 JP2020528323A JP2020528323A JP7257399B2 JP 7257399 B2 JP7257399 B2 JP 7257399B2 JP 2020528323 A JP2020528323 A JP 2020528323A JP 2020528323 A JP2020528323 A JP 2020528323A JP 7257399 B2 JP7257399 B2 JP 7257399B2
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inositol
myo
chiro
composition
weight ratio
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マルティン、モニカ オリバレス
ホヤ、フリスト フォノリャ
メディナ、マリア パス ディアス-ロペロ
ララメンディ、ホセ ルイス ロペス
ラドロン デ ゲバラ、ニコラス メンドーサ
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Biosearch SA
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2020528323A 2017-11-23 2018-04-19 多嚢胞性卵巣症候群に罹患している女性患者における胚着床率を高める方法 Active JP7257399B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382791 2017-11-23
EP17382791.6 2017-11-23
PCT/EP2018/060077 WO2019101368A1 (en) 2017-11-23 2018-04-19 Method for increasing embryo implantation rate in a female subject suffering polycystic ovary syndrome

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JP2021504360A JP2021504360A (ja) 2021-02-15
JP2021504360A5 JP2021504360A5 (https=) 2021-05-27
JP7257399B2 true JP7257399B2 (ja) 2023-04-13

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US (1) US11484540B2 (https=)
EP (1) EP3713552A1 (https=)
JP (1) JP7257399B2 (https=)
CN (1) CN111655245B (https=)
AU (1) AU2018373174B2 (https=)
BR (1) BR112020010343A2 (https=)
CA (1) CA3083301C (https=)
MA (1) MA50784A (https=)
MX (1) MX2020005223A (https=)
NZ (1) NZ765637A (https=)
TW (1) TWI842684B (https=)
WO (1) WO2019101368A1 (https=)

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RU2749783C1 (ru) * 2020-12-11 2021-06-16 Федеральное государственное автономное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет имени Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) Способ лечения синдрома поликистозных яичников, ассоциированного с метаболическим синдромом
CN114159402A (zh) * 2021-12-21 2022-03-11 湖州展望天明药业有限公司 一种不透明植物胶囊及其制备方法
EP4620480A1 (en) 2022-11-16 2025-09-24 Kansai Medical University Educational Corporation Implantation facilitator, and screening system therefor
CN117017929B (zh) * 2023-09-11 2024-11-08 山东奥克斯畜牧种业有限公司 一种用于提高采卵效果的组合物及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006213684A (ja) 2005-02-07 2006-08-17 Hokko Chem Ind Co Ltd インスリン抵抗性改善に用いられる組成物及び健康用食品
WO2013076121A1 (en) 2011-11-22 2013-05-30 Lo.Li. Pharma S.R.L. Pharmaceutical composition comprising myo-inositol and d-chiro-inositol
WO2017179012A1 (en) 2016-04-13 2017-10-19 S&R Farmaceutici S.P.A. Nutraceutical or pharmaceutical composition for use in the treatment of polycystic ovary syndrome or of diseases or disorders related thereto

Family Cites Families (11)

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CA2047686C (en) 1989-03-08 2000-09-05 Joseph Larner Dietary supplement for insulin-resistant diabetics
US5563059A (en) 1993-02-23 1996-10-08 Genentech, Inc. Use of human inhibin and human activin to increase the number of mature primate oocytes
US5906979A (en) * 1998-01-27 1999-05-25 Insmed Pharmaceuticals, Inc. Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility
US7105489B2 (en) * 2002-01-22 2006-09-12 Amylin Pharmaceuticals, Inc. Methods and compositions for treating polycystic ovary syndrome
ITRM20070341A1 (it) * 2007-06-20 2008-12-21 Lo Li Pharma Srl Formulazione integrativa inofolic finalizzata al controllo dell'induzione dell'ovulazione in programmi di procreazione medicalmente assistita
EP2596132A4 (en) 2010-07-23 2013-12-18 Harvard College METHOD FOR DETECTING SIGNS FOR ILLNESS OR SUFFERING IN BODY FLUIDS
ITMI20110445A1 (it) * 2011-03-22 2012-09-23 Lo Li Pharma Srl Formulazione farmaceutica comprendente inositolo.
ITRM20130655A1 (it) * 2013-11-26 2015-05-27 Dicofarm Spa Prodotto a base di una associazione di glucomannano ed inositolo
US9259410B2 (en) 2014-04-08 2016-02-16 Oculus Innovative Sciences, Inc. Methods of treating polycystic ovarian syndrome using chlorogenic acid and inositol
IN2014MU01312A (https=) 2014-04-09 2015-10-16 Olive Healthcare
ITUA20163025A1 (it) * 2016-04-29 2017-10-29 Sochim Int S P A Composizione per il trattamento della sindrome dell’ovaio policistico

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006213684A (ja) 2005-02-07 2006-08-17 Hokko Chem Ind Co Ltd インスリン抵抗性改善に用いられる組成物及び健康用食品
WO2013076121A1 (en) 2011-11-22 2013-05-30 Lo.Li. Pharma S.R.L. Pharmaceutical composition comprising myo-inositol and d-chiro-inositol
WO2017179012A1 (en) 2016-04-13 2017-10-19 S&R Farmaceutici S.P.A. Nutraceutical or pharmaceutical composition for use in the treatment of polycystic ovary syndrome or of diseases or disorders related thereto

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
European Review for Medical and Pharmacological Sciences,2012年,Vol.16,p.575-581
Evaluation of the Mixture Myoinositol:D-chiro-inositol 3.6:1 in Women With Polycystic Ovary Syndrome',NCT03201601, [online],2017年06月28日,[令和4年1月28日検索],インターネット<URL:https://clinicaltrials.gov/ct2/show/NCT03201601>
Expert Rev. clin. Phamacol.,2014年,vol.7, No.5,p.623-631
International Journal of Endocrinology,2016年,Volume 2016,Article ID 3204083

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Publication number Publication date
MX2020005223A (es) 2020-10-19
EP3713552A1 (en) 2020-09-30
MA50784A (fr) 2020-09-30
BR112020010343A2 (pt) 2020-11-10
NZ765637A (en) 2025-11-28
TWI842684B (zh) 2024-05-21
CN111655245A (zh) 2020-09-11
CA3083301A1 (en) 2019-05-31
US11484540B2 (en) 2022-11-01
JP2021504360A (ja) 2021-02-15
RU2020120655A3 (https=) 2021-12-23
TW201924692A (zh) 2019-07-01
AU2018373174A1 (en) 2020-07-09
US20200330495A1 (en) 2020-10-22
CA3083301C (en) 2024-05-21
WO2019101368A1 (en) 2019-05-31
CN111655245B (zh) 2023-08-08
RU2020120655A (ru) 2021-12-23
AU2018373174B2 (en) 2024-07-25

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