CN111655245B - 提高患有多囊卵巢综合征的雌性受试者的胚胎着床率的方法 - Google Patents

提高患有多囊卵巢综合征的雌性受试者的胚胎着床率的方法 Download PDF

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CN111655245B
CN111655245B CN201880087590.2A CN201880087590A CN111655245B CN 111655245 B CN111655245 B CN 111655245B CN 201880087590 A CN201880087590 A CN 201880087590A CN 111655245 B CN111655245 B CN 111655245B
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inositol
composition
chiro
myo
weight ratio
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CN111655245A (zh
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莫妮卡·奥利瓦雷斯·马丁
胡里斯托·福诺拉·何亚
玛丽亚帕斯·迪亚兹罗佩罗·梅迪纳
若泽路易斯·洛佩斯·拉腊门迪
尼古拉斯·门多萨·拉德龙德格瓦拉
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Biosearch SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201880087590.2A 2017-11-23 2018-04-19 提高患有多囊卵巢综合征的雌性受试者的胚胎着床率的方法 Active CN111655245B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382791 2017-11-23
EP17382791.6 2017-11-23
PCT/EP2018/060077 WO2019101368A1 (en) 2017-11-23 2018-04-19 Method for increasing embryo implantation rate in a female subject suffering polycystic ovary syndrome

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CN111655245A CN111655245A (zh) 2020-09-11
CN111655245B true CN111655245B (zh) 2023-08-08

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US (1) US11484540B2 (https=)
EP (1) EP3713552A1 (https=)
JP (1) JP7257399B2 (https=)
CN (1) CN111655245B (https=)
AU (1) AU2018373174B2 (https=)
BR (1) BR112020010343A2 (https=)
CA (1) CA3083301C (https=)
MA (1) MA50784A (https=)
MX (1) MX2020005223A (https=)
NZ (1) NZ765637A (https=)
TW (1) TWI842684B (https=)
WO (1) WO2019101368A1 (https=)

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Publication number Priority date Publication date Assignee Title
RU2749783C1 (ru) * 2020-12-11 2021-06-16 Федеральное государственное автономное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет имени Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) Способ лечения синдрома поликистозных яичников, ассоциированного с метаболическим синдромом
CN114159402A (zh) * 2021-12-21 2022-03-11 湖州展望天明药业有限公司 一种不透明植物胶囊及其制备方法
EP4620480A1 (en) 2022-11-16 2025-09-24 Kansai Medical University Educational Corporation Implantation facilitator, and screening system therefor
CN117017929B (zh) * 2023-09-11 2024-11-08 山东奥克斯畜牧种业有限公司 一种用于提高采卵效果的组合物及其制备方法和应用

Citations (5)

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Publication number Priority date Publication date Assignee Title
CN1291894A (zh) * 1998-01-27 2001-04-18 英斯麦得制药公司 用于治疗以高胰岛素血症、雄激素过多症、高脂血症和/或排卵停止为特征的代谢性疾病的含d－平性－肌醇的组合物
WO2008155651A2 (en) * 2007-06-20 2008-12-24 Lo.Li. Pharma S.R.L. Inositol for induction of ovulation
WO2013076121A1 (en) * 2011-11-22 2013-05-30 Lo.Li. Pharma S.R.L. Pharmaceutical composition comprising myo-inositol and d-chiro-inositol
EP2875809A1 (en) * 2013-11-26 2015-05-27 Dicofarm Spa Product based on an association of glucomannan and inositol
WO2017187375A1 (en) * 2016-04-29 2017-11-02 Sochim International S.P.A. Composition for the treatment of polycystic ovary syndrome

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CA2047686C (en) 1989-03-08 2000-09-05 Joseph Larner Dietary supplement for insulin-resistant diabetics
US5563059A (en) 1993-02-23 1996-10-08 Genentech, Inc. Use of human inhibin and human activin to increase the number of mature primate oocytes
US7105489B2 (en) * 2002-01-22 2006-09-12 Amylin Pharmaceuticals, Inc. Methods and compositions for treating polycystic ovary syndrome
JP2006213684A (ja) 2005-02-07 2006-08-17 Hokko Chem Ind Co Ltd インスリン抵抗性改善に用いられる組成物及び健康用食品
EP2596132A4 (en) 2010-07-23 2013-12-18 Harvard College METHOD FOR DETECTING SIGNS FOR ILLNESS OR SUFFERING IN BODY FLUIDS
ITMI20110445A1 (it) * 2011-03-22 2012-09-23 Lo Li Pharma Srl Formulazione farmaceutica comprendente inositolo.
US9259410B2 (en) 2014-04-08 2016-02-16 Oculus Innovative Sciences, Inc. Methods of treating polycystic ovarian syndrome using chlorogenic acid and inositol
IN2014MU01312A (https=) 2014-04-09 2015-10-16 Olive Healthcare
ITUA20162575A1 (it) 2016-04-13 2017-10-13 S&R Farm S P A Composizione farmaceutica o nutraceutica per l’uso nel trattamento della sindrome dell’ovaio policistico o di malattie o disturbi correlati ad essa

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1291894A (zh) * 1998-01-27 2001-04-18 英斯麦得制药公司 用于治疗以高胰岛素血症、雄激素过多症、高脂血症和/或排卵停止为特征的代谢性疾病的含d－平性－肌醇的组合物
WO2008155651A2 (en) * 2007-06-20 2008-12-24 Lo.Li. Pharma S.R.L. Inositol for induction of ovulation
WO2013076121A1 (en) * 2011-11-22 2013-05-30 Lo.Li. Pharma S.R.L. Pharmaceutical composition comprising myo-inositol and d-chiro-inositol
EP2875809A1 (en) * 2013-11-26 2015-05-27 Dicofarm Spa Product based on an association of glucomannan and inositol
WO2017187375A1 (en) * 2016-04-29 2017-11-02 Sochim International S.P.A. Composition for the treatment of polycystic ovary syndrome

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
D-手性肌醇的研究与开发;张泽生等;《中国食品添加剂》;第第3卷卷(第第3期期);第77-83页 *

Also Published As

Publication number Publication date
JP7257399B2 (ja) 2023-04-13
MX2020005223A (es) 2020-10-19
EP3713552A1 (en) 2020-09-30
MA50784A (fr) 2020-09-30
BR112020010343A2 (pt) 2020-11-10
NZ765637A (en) 2025-11-28
TWI842684B (zh) 2024-05-21
CN111655245A (zh) 2020-09-11
CA3083301A1 (en) 2019-05-31
US11484540B2 (en) 2022-11-01
JP2021504360A (ja) 2021-02-15
RU2020120655A3 (https=) 2021-12-23
TW201924692A (zh) 2019-07-01
AU2018373174A1 (en) 2020-07-09
US20200330495A1 (en) 2020-10-22
CA3083301C (en) 2024-05-21
WO2019101368A1 (en) 2019-05-31
RU2020120655A (ru) 2021-12-23
AU2018373174B2 (en) 2024-07-25

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