JP7241761B2 - 構成可能な流体混合システムのハウジングおよび支援ハードウェア - Google Patents

構成可能な流体混合システムのハウジングおよび支援ハードウェア Download PDF

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JP7241761B2
JP7241761B2 JP2020539092A JP2020539092A JP7241761B2 JP 7241761 B2 JP7241761 B2 JP 7241761B2 JP 2020539092 A JP2020539092 A JP 2020539092A JP 2020539092 A JP2020539092 A JP 2020539092A JP 7241761 B2 JP7241761 B2 JP 7241761B2
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cable
assembly
flexible container
various embodiments
housing
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JP2021510524A (ja
JP2021510524A5 (enExample
Inventor
ニーファイ ジョーンズ
スティーヴン クジャー
ダニエル プライス
マーク スミス
ポール タッカー
トニー シャオ
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ライフ テクノロジーズ コーポレーション
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/11Stirrers characterised by the configuration of the stirrers
    • B01F27/113Propeller-shaped stirrers for producing an axial flow, e.g. shaped like a ship or aircraft propeller
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/58Reaction vessels connected in series or in parallel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20Mixing gases with liquids
    • B01F23/23Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/051Stirrers characterised by their elements, materials or mechanical properties
    • B01F27/054Deformable stirrers, e.g. deformed by a centrifugal force applied during operation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/07Stirrers characterised by their mounting on the shaft
    • B01F27/071Fixing of the stirrer to the shaft
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/11Stirrers characterised by the configuration of the stirrers
    • B01F27/114Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/21Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by their rotating shafts
    • B01F27/211Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by their rotating shafts characterised by the material of the shaft
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/21Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by their rotating shafts
    • B01F27/212Construction of the shaft
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/21Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by their rotating shafts
    • B01F27/213Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by their rotating shafts characterised by the connection with the drive
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/23Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis
    • B01F27/232Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis with two or more rotation axes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/91Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with propellers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/92Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with helices or screws
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/32005Type of drive
    • B01F35/3204Motor driven, i.e. by means of an electric or IC motor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/41Mounting or supporting stirrer shafts or stirrer units on receptacles
    • B01F35/412Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting both extremities of the shaft
    • B01F35/4121Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting both extremities of the shaft at the top and at the bottom of the receptacle, e.g. for performing a conical orbital movement about a vertical axis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/43Supporting receptacles on frames or stands
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50Mixing receptacles
    • B01F35/513Flexible receptacles, e.g. bags supported by rigid containers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/50Means for positioning or orientating the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • C12M27/06Stirrer or mobile mixing elements with horizontal or inclined stirrer shaft or axis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F2035/35Use of other general mechanical engineering elements in mixing devices
    • B01F2035/352Bearings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20Mixing gases with liquids
    • B01F23/23Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • B01F23/2336Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the location of the place of introduction of the gas relative to the stirrer
    • B01F23/23362Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the location of the place of introduction of the gas relative to the stirrer the gas being introduced under the stirrer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/90Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms 
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/321Disposition of the drive
    • B01F35/3214Disposition of the drive at the upper side of the axis, e.g. driving the stirrer from the top of a receptacle
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2527/00Culture process characterised by the use of mechanical forces, e.g. strain, vibration

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Computer Hardware Design (AREA)
  • Aviation & Aerospace Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Accessories For Mixers (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2020539092A 2018-01-17 2019-01-03 構成可能な流体混合システムのハウジングおよび支援ハードウェア Active JP7241761B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023034912A JP7566955B2 (ja) 2018-01-17 2023-03-07 構成可能な流体混合システムのハウジングおよび支援ハードウェア

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862618215P 2018-01-17 2018-01-17
US62/618,215 2018-01-17
US201862670934P 2018-05-14 2018-05-14
US62/670,934 2018-05-14
US201862712343P 2018-07-31 2018-07-31
US62/712,343 2018-07-31
PCT/US2019/012126 WO2019143478A1 (en) 2018-01-17 2019-01-03 Configurable fluid mixing system housing and support hardware

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023034912A Division JP7566955B2 (ja) 2018-01-17 2023-03-07 構成可能な流体混合システムのハウジングおよび支援ハードウェア

Publications (3)

Publication Number Publication Date
JP2021510524A JP2021510524A (ja) 2021-04-30
JP2021510524A5 JP2021510524A5 (enExample) 2021-12-09
JP7241761B2 true JP7241761B2 (ja) 2023-03-17

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ID=65199609

Family Applications (7)

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JP2020539093A Active JP7223012B2 (ja) 2018-01-17 2019-01-03 インペラアタッチメントを備えた、らせん状混合アセンブリを含む流体混合システムおよび使用方法
JP2020539064A Pending JP2021511033A (ja) 2018-01-17 2019-01-03 細胞培養規模拡縮のためのシステムおよび方法
JP2020539092A Active JP7241761B2 (ja) 2018-01-17 2019-01-03 構成可能な流体混合システムのハウジングおよび支援ハードウェア
JP2022192703A Active JP7465331B2 (ja) 2018-01-17 2022-12-01 インペラアタッチメントを備えた、らせん状混合アセンブリを含む流体混合システムおよび使用方法
JP2023034912A Active JP7566955B2 (ja) 2018-01-17 2023-03-07 構成可能な流体混合システムのハウジングおよび支援ハードウェア
JP2023098465A Abandoned JP2023107983A (ja) 2018-01-17 2023-06-15 細胞培養規模拡縮のためのシステムおよび方法
JP2024055958A Abandoned JP2024071715A (ja) 2018-01-17 2024-03-29 インペラアタッチメントを備えた、らせん状混合アセンブリを含む流体混合システムおよび使用方法

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JP2020539093A Active JP7223012B2 (ja) 2018-01-17 2019-01-03 インペラアタッチメントを備えた、らせん状混合アセンブリを含む流体混合システムおよび使用方法
JP2020539064A Pending JP2021511033A (ja) 2018-01-17 2019-01-03 細胞培養規模拡縮のためのシステムおよび方法

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JP2022192703A Active JP7465331B2 (ja) 2018-01-17 2022-12-01 インペラアタッチメントを備えた、らせん状混合アセンブリを含む流体混合システムおよび使用方法
JP2023034912A Active JP7566955B2 (ja) 2018-01-17 2023-03-07 構成可能な流体混合システムのハウジングおよび支援ハードウェア
JP2023098465A Abandoned JP2023107983A (ja) 2018-01-17 2023-06-15 細胞培養規模拡縮のためのシステムおよび方法
JP2024055958A Abandoned JP2024071715A (ja) 2018-01-17 2024-03-29 インペラアタッチメントを備えた、らせん状混合アセンブリを含む流体混合システムおよび使用方法

Country Status (5)

Country Link
US (7) US11584910B2 (enExample)
EP (3) EP3740559A1 (enExample)
JP (7) JP7223012B2 (enExample)
CN (4) CN111615554B (enExample)
WO (3) WO2019143478A1 (enExample)

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JP7223012B2 (ja) * 2018-01-17 2023-02-15 ライフ テクノロジーズ コーポレーション インペラアタッチメントを備えた、らせん状混合アセンブリを含む流体混合システムおよび使用方法
USD894377S1 (en) * 2019-01-03 2020-08-25 Life Technologies Corporation Tube management assembly
US11535421B2 (en) * 2019-12-30 2022-12-27 Global Life Sciences Solutions Usa Llc System and method for packaging a bioprocessing bag and associated components, and packaging for a bioprocessing bag
US12138605B2 (en) 2020-02-03 2024-11-12 Life Technologies Corporation Fluid mixing systems with modular impellers and related methods
US12005403B2 (en) * 2020-08-06 2024-06-11 Signature Science, Llc Mixing chamber apparatus for high-volume sampling
CN112246173B (zh) * 2020-09-29 2022-11-04 广州市爱百伊生物技术有限公司 一种配料罐及生产线
EP4225884A1 (en) * 2020-10-08 2023-08-16 Global Life Sciences Solutions USA LLC Bioprocessing system and apparatus for reducing cell shear in a bioprocessing system
US11649654B2 (en) * 2020-10-12 2023-05-16 Cytiva Us Llc Tank with door locking mechanism
DK4323093T3 (da) * 2021-04-16 2025-11-10 Emd Millipore Corp Fleksibel engangs-sparger
CN117597189A (zh) * 2021-06-30 2024-02-23 康宁股份有限公司 用于台式生物反应器的宏观鼓泡器
WO2023021571A1 (ja) * 2021-08-17 2023-02-23 日揮株式会社 演算装置、制御装置、培養システム、及び培養システムの設計方法
CN114210520B (zh) * 2021-12-08 2023-03-14 佛山市亨力豪机械有限公司 一种淋胶机
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