JP7237586B2 - 修飾ナノポア、それを含む組成物およびその使用 - Google Patents

修飾ナノポア、それを含む組成物およびその使用 Download PDF

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JP7237586B2
JP7237586B2 JP2018530754A JP2018530754A JP7237586B2 JP 7237586 B2 JP7237586 B2 JP 7237586B2 JP 2018530754 A JP2018530754 A JP 2018530754A JP 2018530754 A JP2018530754 A JP 2018530754A JP 7237586 B2 JP7237586 B2 JP 7237586B2
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nanopore
amino acid
clya
dna
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マグリア，ジオバンニ
フランチェスキニ，ロレンゾ
ブラウンス，タイン
ジョン ヘロン，アンドリュー
ニシャンタ ジャヤシンゲ，ラクマル
ジェーン ウォーレス，エリザベス
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カトリック ユニヴェルシテット ルーヴェン カーユー ルーヴェン リサーチ アンド ディベロップメント
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2018530754A 2015-12-08 2016-12-08 修飾ナノポア、それを含む組成物およびその使用 Active JP7237586B2 (ja)

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US201562264709P 2015-12-08 2015-12-08
US62/264,709 2015-12-08
PCT/IB2016/001841 WO2017098322A1 (en) 2015-12-08 2016-12-08 Modified nanopores, compositions comprising the same, and uses thereof

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ＦＲＡＮＣＥＳＣＨＩＮＩ， Ｌｏｒｅｎｚｏ ｅｔ ａｌ．，Ａ ＮＡＮＯＰＯＲＥ ＭＡＣＨＩＮＥ ＰＲＯＭＯＴＥＳ ＴＨＥ ＶＥＣＴＯＲＩＡＬ ＴＲＡＮＳＰＯＲＴ ＯＦ ＤＮＡ ＡＣＲＯＳＳ ＭＥＭＢＲＡＮＥＳ，ＮＡＴＵＲＥ ＣＯＭＭＵＮＩＣＡＴＩＯＮＳ，ＭＡＣＭＩＬＬＡＮ ＰＵＢＬＩＳＨＥＲＳ ＬＩＭＩＴＥＤ，２０１３年 ９月，Ｖｏｌ． ４， ２４１５，ｐｐ． １－８，ＵＲＬ，ｈｔｔｐｓ：／／ｗｗｗ．ｎａｔｕｒｅ．ｃｏｍ／ａｒｔｉｃｌｅｓ／ｎｃｏｍｍｓ３４１５

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CN109072295A (zh) 2018-12-21
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JP2019507583A (ja) 2019-03-22
AU2016369071A1 (en) 2018-06-28
KR20180089499A (ko) 2018-08-08
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CN109072295B (zh) 2022-05-31
WO2017098322A1 (en) 2017-06-15
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