JP6997038B2 - マイクロニードルアレイの製造方法 - Google Patents

マイクロニードルアレイの製造方法 Download PDF

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Publication number
JP6997038B2
JP6997038B2 JP2018094789A JP2018094789A JP6997038B2 JP 6997038 B2 JP6997038 B2 JP 6997038B2 JP 2018094789 A JP2018094789 A JP 2018094789A JP 2018094789 A JP2018094789 A JP 2018094789A JP 6997038 B2 JP6997038 B2 JP 6997038B2
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JP
Japan
Prior art keywords
mold
filling
liquid
needle
microneedle array
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Application number
JP2018094789A
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English (en)
Japanese (ja)
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JP2019198479A (ja
JP2019198479A5 (enExample
Inventor
良樹 坂▲崎▼
行央 高野
哲史 若松
圭央 岡野
健一郎 玉木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Corp
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Fujifilm Corp
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Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Priority to JP2018094789A priority Critical patent/JP6997038B2/ja
Priority to EP19169862.0A priority patent/EP3569281B1/en
Priority to CN201910327480.5A priority patent/CN110496304A/zh
Priority to US16/391,338 priority patent/US11452854B2/en
Publication of JP2019198479A publication Critical patent/JP2019198479A/ja
Publication of JP2019198479A5 publication Critical patent/JP2019198479A5/ja
Application granted granted Critical
Publication of JP6997038B2 publication Critical patent/JP6997038B2/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C39/10Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles incorporating preformed parts or layers, e.g. casting around inserts or for coating articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/22Component parts, details or accessories; Auxiliary operations
    • B29C39/42Casting under special conditions, e.g. vacuum
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/22Component parts, details or accessories; Auxiliary operations
    • B29C39/44Measuring, controlling or regulating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production
    • A61M2207/10Device therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0005Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
    • B29K2105/0035Medical or pharmaceutical agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058Liquid or visquous
    • B29K2105/0073Solution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/753Medical equipment; Accessories therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP2018094789A 2018-05-16 2018-05-16 マイクロニードルアレイの製造方法 Active JP6997038B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2018094789A JP6997038B2 (ja) 2018-05-16 2018-05-16 マイクロニードルアレイの製造方法
EP19169862.0A EP3569281B1 (en) 2018-05-16 2019-04-17 Method of manufacturing microneedle array
CN201910327480.5A CN110496304A (zh) 2018-05-16 2019-04-23 微针阵列的制造方法
US16/391,338 US11452854B2 (en) 2018-05-16 2019-04-23 Method of manufacturing microneedle array

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2018094789A JP6997038B2 (ja) 2018-05-16 2018-05-16 マイクロニードルアレイの製造方法

Publications (3)

Publication Number Publication Date
JP2019198479A JP2019198479A (ja) 2019-11-21
JP2019198479A5 JP2019198479A5 (enExample) 2020-09-10
JP6997038B2 true JP6997038B2 (ja) 2022-01-17

Family

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Family Applications (1)

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JP2018094789A Active JP6997038B2 (ja) 2018-05-16 2018-05-16 マイクロニードルアレイの製造方法

Country Status (4)

Country Link
US (1) US11452854B2 (enExample)
EP (1) EP3569281B1 (enExample)
JP (1) JP6997038B2 (enExample)
CN (1) CN110496304A (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018215324A1 (de) * 2018-09-10 2020-03-12 Lts Lohmann Therapie-Systeme Ag Vorrichtung und Verfahren zur Herstellung von Mikrostrukturen
JP1664599S (enExample) * 2019-09-19 2020-07-27
JP1664598S (enExample) * 2019-09-19 2020-07-27
JP1664520S (enExample) * 2019-09-19 2020-07-27
DE102020104320A1 (de) * 2020-02-19 2021-08-19 Lts Lohmann Therapie-Systeme Ag Mikronadel-Array, Formkörper zur Herstellung eines Mikronadel-Arrays sowie Verfahren zur Herstellung eines Mikronadel-Arrays
CN111467667B (zh) * 2020-04-17 2020-12-04 南京鼓楼医院 一种多层微针阵列及其制备方法
US20220008007A1 (en) * 2020-07-13 2022-01-13 Icreate Technology (Zhuhai) Co., Ltd. Microneedle array and sensor including the same
DE102021100396A1 (de) * 2021-01-12 2022-07-14 Lts Lohmann Therapie-Systeme Ag. Verfahren und System zur Herstellung von Mikrostrukturen
KR102382088B1 (ko) * 2021-12-14 2022-04-04 주식회사 대웅테라퓨틱스 마이크로니들 제조방법
KR102427901B1 (ko) * 2022-01-28 2022-08-02 주식회사 대웅테라퓨틱스 마이크로니들 제조방법

Citations (6)

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JP2004106399A (ja) 2002-09-19 2004-04-08 Canon Inc 光学素子の成形方法及び製造装置及び光学スクリーン
JP2008124306A (ja) 2006-11-14 2008-05-29 Hinstec Co Ltd プリント基板の穴充填部欠陥検査システム及び欠陥検査方法
JP2013153866A (ja) 2012-01-27 2013-08-15 Fujifilm Corp 経皮吸収シート及び経皮吸収シートの製造方法
CN105498082A (zh) 2015-12-24 2016-04-20 广州新济药业科技有限公司 微针芯片及其制备方法
JP2016112169A (ja) 2014-12-15 2016-06-23 日本写真印刷株式会社 マイクロニードルアレイ製造装置及びマイクロニードルアレイの製造方法並びにマイクロニードルアレイを有する製品
JP2016170164A (ja) 2015-03-10 2016-09-23 富士フイルム株式会社 測定方法及び測定装置及びプログラム

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JP2771190B2 (ja) * 1988-10-07 1998-07-02 株式会社日立製作所 スルーホール充填状態検査方法およびその装置
JP2008175549A (ja) * 2007-01-16 2008-07-31 Olympus Corp 欠陥検出装置および欠陥検出方法
AU2010238605B2 (en) * 2009-04-24 2015-10-29 Corium Pharma Solutions, Inc. Methods for manufacturing microprojection arrays
JP2011224332A (ja) 2010-03-29 2011-11-10 Fujifilm Corp 経皮吸収シート及びその製造方法
JP5886535B2 (ja) 2011-03-28 2016-03-16 東レエンジニアリング株式会社 マイクロニードルシートの製造方法
JP2013162982A (ja) * 2012-02-13 2013-08-22 Fujifilm Corp マイクロニードルシートの製造方法
JP6038173B2 (ja) 2012-11-13 2016-12-07 富士フイルム株式会社 経皮吸収シートの製造方法
JP6268114B2 (ja) * 2015-03-09 2018-01-24 富士フイルム株式会社 マイクロニードルの検査方法
JP6355262B2 (ja) * 2015-03-10 2018-07-11 富士フイルム株式会社 計測システム、計測方法及び計測プログラム
JP6411395B2 (ja) 2015-03-10 2018-10-24 富士フイルム株式会社 経皮吸収シートの製造方法
JP6395694B2 (ja) * 2015-03-10 2018-09-26 富士フイルム株式会社 測定方法及び測定装置及びプログラム
KR101795566B1 (ko) * 2016-01-05 2017-11-09 경기대학교 산학협력단 그래핀 검사 장치 및 방법
JP6326445B2 (ja) * 2016-04-22 2018-05-16 株式会社Screenホールディングス 画像処理方法、画像処理装置、および画像処理プログラム
JP6700144B2 (ja) * 2016-09-06 2020-05-27 富士フイルム株式会社 マイクロニードルアレイ撮像方法及びマイクロニードルアレイ検査方法
CN107569767A (zh) * 2017-09-01 2018-01-12 东莞市睿奇电子科技有限公司 一种微针及其制造方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004106399A (ja) 2002-09-19 2004-04-08 Canon Inc 光学素子の成形方法及び製造装置及び光学スクリーン
JP2008124306A (ja) 2006-11-14 2008-05-29 Hinstec Co Ltd プリント基板の穴充填部欠陥検査システム及び欠陥検査方法
JP2013153866A (ja) 2012-01-27 2013-08-15 Fujifilm Corp 経皮吸収シート及び経皮吸収シートの製造方法
JP2016112169A (ja) 2014-12-15 2016-06-23 日本写真印刷株式会社 マイクロニードルアレイ製造装置及びマイクロニードルアレイの製造方法並びにマイクロニードルアレイを有する製品
JP2016170164A (ja) 2015-03-10 2016-09-23 富士フイルム株式会社 測定方法及び測定装置及びプログラム
CN105498082A (zh) 2015-12-24 2016-04-20 广州新济药业科技有限公司 微针芯片及其制备方法

Also Published As

Publication number Publication date
US20190351204A1 (en) 2019-11-21
EP3569281A1 (en) 2019-11-20
CN110496304A (zh) 2019-11-26
JP2019198479A (ja) 2019-11-21
EP3569281B1 (en) 2022-03-30
US11452854B2 (en) 2022-09-27

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