CN110496304A - 微针阵列的制造方法 - Google Patents

微针阵列的制造方法 Download PDF

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Publication number
CN110496304A
CN110496304A CN201910327480.5A CN201910327480A CN110496304A CN 110496304 A CN110496304 A CN 110496304A CN 201910327480 A CN201910327480 A CN 201910327480A CN 110496304 A CN110496304 A CN 110496304A
Authority
CN
China
Prior art keywords
mold
liquid
needle
pharmacy solution
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910327480.5A
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English (en)
Chinese (zh)
Inventor
坂崎良树
高野行央
若松哲史
冈野圭央
玉木健一郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Corp
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Publication of CN110496304A publication Critical patent/CN110496304A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C39/10Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles incorporating preformed parts or layers, e.g. casting around inserts or for coating articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/22Component parts, details or accessories; Auxiliary operations
    • B29C39/42Casting under special conditions, e.g. vacuum
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/22Component parts, details or accessories; Auxiliary operations
    • B29C39/44Measuring, controlling or regulating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production
    • A61M2207/10Device therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0005Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
    • B29K2105/0035Medical or pharmaceutical agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058Liquid or visquous
    • B29K2105/0073Solution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/753Medical equipment; Accessories therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN201910327480.5A 2018-05-16 2019-04-23 微针阵列的制造方法 Pending CN110496304A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018094789A JP6997038B2 (ja) 2018-05-16 2018-05-16 マイクロニードルアレイの製造方法
JP2018-094789 2018-05-16

Publications (1)

Publication Number Publication Date
CN110496304A true CN110496304A (zh) 2019-11-26

Family

ID=66217953

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910327480.5A Pending CN110496304A (zh) 2018-05-16 2019-04-23 微针阵列的制造方法

Country Status (4)

Country Link
US (1) US11452854B2 (enExample)
EP (1) EP3569281B1 (enExample)
JP (1) JP6997038B2 (enExample)
CN (1) CN110496304A (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111467667A (zh) * 2020-04-17 2020-07-31 南京鼓楼医院 一种多层微针阵列及其制备方法
CN112654388A (zh) * 2018-09-10 2021-04-13 Lts洛曼治疗系统股份公司 用于制造微结构的装置和方法

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP1664599S (enExample) * 2019-09-19 2020-07-27
JP1664598S (enExample) * 2019-09-19 2020-07-27
JP1664520S (enExample) * 2019-09-19 2020-07-27
DE102020104320A1 (de) * 2020-02-19 2021-08-19 Lts Lohmann Therapie-Systeme Ag Mikronadel-Array, Formkörper zur Herstellung eines Mikronadel-Arrays sowie Verfahren zur Herstellung eines Mikronadel-Arrays
US20220008007A1 (en) * 2020-07-13 2022-01-13 Icreate Technology (Zhuhai) Co., Ltd. Microneedle array and sensor including the same
DE102021100396A1 (de) * 2021-01-12 2022-07-14 Lts Lohmann Therapie-Systeme Ag. Verfahren und System zur Herstellung von Mikrostrukturen
KR102382088B1 (ko) * 2021-12-14 2022-04-04 주식회사 대웅테라퓨틱스 마이크로니들 제조방법
KR102427901B1 (ko) * 2022-01-28 2022-08-02 주식회사 대웅테라퓨틱스 마이크로니들 제조방법

Citations (20)

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US5015097A (en) * 1988-10-07 1991-05-14 Hitachi, Ltd. Method for inspecting filled state of via-holes filled with fillers and apparatus for carrying out the method
JP2004106399A (ja) * 2002-09-19 2004-04-08 Canon Inc 光学素子の成形方法及び製造装置及び光学スクリーン
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JP2012200572A (ja) * 2011-03-28 2012-10-22 Toray Eng Co Ltd マイクロニードルシートおよびその製造方法
JP2013153866A (ja) * 2012-01-27 2013-08-15 Fujifilm Corp 経皮吸収シート及び経皮吸収シートの製造方法
JP2013162982A (ja) * 2012-02-13 2013-08-22 Fujifilm Corp マイクロニードルシートの製造方法
CN104780967A (zh) * 2012-11-13 2015-07-15 富士胶片株式会社 经皮吸收片的制造方法
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JP2016166769A (ja) * 2015-03-09 2016-09-15 富士フイルム株式会社 マイクロニードルの検査方法
WO2017119715A1 (ko) * 2016-01-05 2017-07-13 경기대학교 산학협력단 그래핀 검사 장치 및 방법
EP3235537A1 (en) * 2014-12-15 2017-10-25 Nissha Printing Co., Ltd. Microneedle-array production device, microneedle-array production method, and article provided with microneedle array
WO2017183441A1 (ja) * 2016-04-22 2017-10-26 株式会社Screenホールディングス 画像処理方法、画像処理装置、および画像処理プログラム
CN107405478A (zh) * 2015-03-10 2017-11-28 富士胶片株式会社 经皮吸收片的制造方法
CN107569767A (zh) * 2017-09-01 2018-01-12 东莞市睿奇电子科技有限公司 一种微针及其制造方法
US20180058903A1 (en) * 2015-03-10 2018-03-01 Fujifilm Corporation Measurement method, measurement device, and program
US20180058902A1 (en) * 2015-03-10 2018-03-01 Fujifilm Corporation Measurement system, measurement method, and measurement program
US20180066938A1 (en) * 2015-03-10 2018-03-08 Fujifilm Corporation Measurement method, measurement device, and program
JP2018038509A (ja) * 2016-09-06 2018-03-15 富士フイルム株式会社 マイクロニードルアレイ撮像装置及び方法、並びに、マイクロニードルアレイ検査装置及び方法

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AU2010238605B2 (en) * 2009-04-24 2015-10-29 Corium Pharma Solutions, Inc. Methods for manufacturing microprojection arrays

Patent Citations (20)

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US5015097A (en) * 1988-10-07 1991-05-14 Hitachi, Ltd. Method for inspecting filled state of via-holes filled with fillers and apparatus for carrying out the method
JP2004106399A (ja) * 2002-09-19 2004-04-08 Canon Inc 光学素子の成形方法及び製造装置及び光学スクリーン
JP2008124306A (ja) * 2006-11-14 2008-05-29 Hinstec Co Ltd プリント基板の穴充填部欠陥検査システム及び欠陥検査方法
CN101600957A (zh) * 2007-01-16 2009-12-09 奥林巴斯株式会社 缺陷检测装置及缺陷检测方法
JP2011224332A (ja) * 2010-03-29 2011-11-10 Fujifilm Corp 経皮吸収シート及びその製造方法
JP2012200572A (ja) * 2011-03-28 2012-10-22 Toray Eng Co Ltd マイクロニードルシートおよびその製造方法
JP2013153866A (ja) * 2012-01-27 2013-08-15 Fujifilm Corp 経皮吸収シート及び経皮吸収シートの製造方法
JP2013162982A (ja) * 2012-02-13 2013-08-22 Fujifilm Corp マイクロニードルシートの製造方法
CN104780967A (zh) * 2012-11-13 2015-07-15 富士胶片株式会社 经皮吸收片的制造方法
EP3235537A1 (en) * 2014-12-15 2017-10-25 Nissha Printing Co., Ltd. Microneedle-array production device, microneedle-array production method, and article provided with microneedle array
JP2016166769A (ja) * 2015-03-09 2016-09-15 富士フイルム株式会社 マイクロニードルの検査方法
CN107405478A (zh) * 2015-03-10 2017-11-28 富士胶片株式会社 经皮吸收片的制造方法
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WO2017119715A1 (ko) * 2016-01-05 2017-07-13 경기대학교 산학협력단 그래핀 검사 장치 및 방법
WO2017183441A1 (ja) * 2016-04-22 2017-10-26 株式会社Screenホールディングス 画像処理方法、画像処理装置、および画像処理プログラム
JP2018038509A (ja) * 2016-09-06 2018-03-15 富士フイルム株式会社 マイクロニードルアレイ撮像装置及び方法、並びに、マイクロニードルアレイ検査装置及び方法
CN107569767A (zh) * 2017-09-01 2018-01-12 东莞市睿奇电子科技有限公司 一种微针及其制造方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112654388A (zh) * 2018-09-10 2021-04-13 Lts洛曼治疗系统股份公司 用于制造微结构的装置和方法
US12458785B2 (en) 2018-09-10 2025-11-04 Lts Lohmann Therapie-Systeme Ag Device and method for producing microstructures
CN111467667A (zh) * 2020-04-17 2020-07-31 南京鼓楼医院 一种多层微针阵列及其制备方法
CN111467667B (zh) * 2020-04-17 2020-12-04 南京鼓楼医院 一种多层微针阵列及其制备方法

Also Published As

Publication number Publication date
US20190351204A1 (en) 2019-11-21
EP3569281A1 (en) 2019-11-20
JP6997038B2 (ja) 2022-01-17
JP2019198479A (ja) 2019-11-21
EP3569281B1 (en) 2022-03-30
US11452854B2 (en) 2022-09-27

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