JP6993958B2 - 多重特異性抗原結合分子およびその使用 - Google Patents

多重特異性抗原結合分子およびその使用 Download PDF

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JP6993958B2
JP6993958B2 JP2018500528A JP2018500528A JP6993958B2 JP 6993958 B2 JP6993958 B2 JP 6993958B2 JP 2018500528 A JP2018500528 A JP 2018500528A JP 2018500528 A JP2018500528 A JP 2018500528A JP 6993958 B2 JP6993958 B2 JP 6993958B2
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antibody
prlr
her2
binding
drug
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JP2018524358A5 (OSRAM
JP2018524358A (ja
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ジュリアン アンドレーエフ
ニスヤ タンビ
フランク デルフィノ
ジョエル マーティン
ギャビン サーストン
キャサリン シグナー
ニコラス パパドプロス
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Regeneron Pharmaceuticals Inc
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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