JP6915943B2 - 診断およびインビボイメージングのための化学発光プローブ - Google Patents

診断およびインビボイメージングのための化学発光プローブ Download PDF

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JP6915943B2
JP6915943B2 JP2018539034A JP2018539034A JP6915943B2 JP 6915943 B2 JP6915943 B2 JP 6915943B2 JP 2018539034 A JP2018539034 A JP 2018539034A JP 2018539034 A JP2018539034 A JP 2018539034A JP 6915943 B2 JP6915943 B2 JP 6915943B2
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alkyl
alkylene
absent
group
probe
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JP2019509981A (ja
JP2019509981A5 (enExample
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シャバット，ドロン
サッチ−ファイナロ，ロニット
ハナンヤ，ニル
グリーン，オリ
エイロン，タル
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Ramot at Tel Aviv University Ltd
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    • A61K49/00—Preparations for testing in vivo
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JP2018539034A 2016-01-26 2017-01-24 診断およびインビボイメージングのための化学発光プローブ Active JP6915943B2 (ja)

Applications Claiming Priority (5)

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US201662287127P 2016-01-26 2016-01-26
US62/287,127 2016-01-26
US201662431618P 2016-12-08 2016-12-08
US62/431,618 2016-12-08
PCT/IL2017/050088 WO2017130191A1 (en) 2016-01-26 2017-01-24 Chemiluminescent probes for diagnostics and in vivo imaging

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JP2019509981A JP2019509981A (ja) 2019-04-11
JP2019509981A5 JP2019509981A5 (enExample) 2020-02-13
JP6915943B2 true JP6915943B2 (ja) 2021-08-11

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KR (1) KR102717614B1 (enExample)
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CA (1) CA3011328C (enExample)
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WO2018216012A1 (en) 2017-05-24 2018-11-29 Ramot At Tel-Aviv University Ltd. Chemiluminescent probes for imaging/detection of proteases
WO2019224339A1 (en) 2018-05-25 2019-11-28 Biosynth Ag Long wavelength emitting chemiluminescent probes
US11649475B2 (en) * 2018-05-25 2023-05-16 Ramot At Tel-Aviv University Ltd. Dioxetane compounds and their use for the detection of microorganisms
CN111073633B (zh) * 2018-10-22 2023-07-25 北京工商大学 一种萘环类苯硫酚荧光探针
WO2020159448A1 (en) * 2019-02-01 2020-08-06 Nanyang Technological University Molecular renal probes for detecting acute kidney injury
CN110437274A (zh) * 2019-08-28 2019-11-12 南京工业大学 一种用于检测氟离子的探针、制备方法及应用
CN110804009B (zh) * 2019-10-10 2025-12-12 华东理工大学 一类化学发光强度高、波长长、稳定性好的化学发光底物及其制备方法和应用
WO2021086977A1 (en) * 2019-10-28 2021-05-06 Beckman Coulter, Inc. Rapid, high-intensity chemiluminescent dioxetanes
KR102332454B1 (ko) * 2019-12-18 2021-11-29 고려대학교 산학협력단 암 세포 검출용 발광 프로브 화합물 및 이를 포함하는 암 세포 검출용 발광 센서
US20240277873A1 (en) * 2021-08-11 2024-08-22 Nanyang Technological University Ultrabright chemiluminescent probes for detection and imaging
CN114315791B (zh) * 2021-12-22 2023-12-08 东南大学 用于实现手术导航和微小转移瘤成像的小分子化学发光探针及其制备方法和用途
CN114478473B (zh) * 2022-01-25 2024-05-03 南方医科大学 一种亮氨酸氨基肽酶化学发光检测试剂的合成及应用
JP2023110666A (ja) 2022-01-28 2023-08-09 シスメックス株式会社 化合物またはその塩、組成物、化学発光方法、化学発光シグナル測定方法、試薬、試薬キットおよび被検物質測定方法
CN115417863B (zh) * 2022-09-30 2024-02-02 徐州医科大学 一种二氧化硫近红外化学发光探针及其制备方法和应用
CN115894581B (zh) * 2022-10-26 2024-07-09 徐州医科大学 一种β-葡萄糖醛酸苷酶化学发光探针及其制备方法和应用
CN115819416B (zh) * 2022-11-29 2024-06-25 遵义医科大学 一种用于检测和区分的多模态化学发光分子及其应用
CN116217515B (zh) * 2022-12-20 2024-06-18 华南师范大学 一种亚甲基蓝型探针及其制备方法和在检测半胱氨酸中的应用
WO2024147125A1 (en) * 2023-01-04 2024-07-11 Ramot At Tel-Aviv University Ltd. Cyclobutyl-substituted phenoxy-dioxetanes and uses thereof
CN116606220A (zh) * 2023-03-21 2023-08-18 华东理工大学 一种单组分有机余辉化合物及其生物检测的应用
CN116410064A (zh) * 2023-04-13 2023-07-11 西安交通大学 一种合成2-(α-甲氧基-3-羟基苯亚甲基)金刚烷类化合物的方法
CN116655716A (zh) * 2023-04-27 2023-08-29 湖南师范大学 一种检测β-半乳糖苷酶的化学发光探针、制备方法及其应用
US20240386087A1 (en) 2023-05-17 2024-11-21 The Government of the United States of America, as represented by the Secretary of Homeland Security DNA Access Control System
CN117059804B (zh) * 2023-10-13 2024-03-19 瑞浦兰钧能源股份有限公司 一种化学预锂剂、锂离子电池及其制备方法
CN117442269B (zh) * 2023-12-22 2024-12-20 中日友好医院(中日友好临床医学研究所) 一种手术缝合针的搜寻系统及方法
CN119409748A (zh) * 2025-01-06 2025-02-11 四川省医学科学院·四川省人民医院 一种N-乙酰-β-D-氨基葡萄糖酶的化学发光探针、试剂盒及其制备方法和应用
CN119798211A (zh) * 2025-01-23 2025-04-11 西安交通大学 一种巯基化合物激活型化学发光探针及其合成方法和应用

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EP3408349B1 (en) 2021-03-31
US10660974B2 (en) 2020-05-26
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EP3408349A1 (en) 2018-12-05
CA3011328C (en) 2024-09-17
US11931429B2 (en) 2024-03-19
ES2866900T3 (es) 2021-10-20
US20220047725A1 (en) 2022-02-17
US20240197924A1 (en) 2024-06-20
JP2019509981A (ja) 2019-04-11
CN108884386A (zh) 2018-11-23
KR102717614B1 (ko) 2024-10-16
CN108884386B (zh) 2022-03-15
US20190290787A1 (en) 2019-09-26
CA3011328A1 (en) 2017-08-03
BR112018015334A2 (pt) 2018-12-18
KR20180108697A (ko) 2018-10-04
US12357709B2 (en) 2025-07-15
US20200237932A1 (en) 2020-07-30
US11179482B2 (en) 2021-11-23

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