JP6807742B2 - カテーテルおよび圧力源を用いて送達する治療薬 - Google Patents
カテーテルおよび圧力源を用いて送達する治療薬 Download PDFInfo
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- JP6807742B2 JP6807742B2 JP2016520011A JP2016520011A JP6807742B2 JP 6807742 B2 JP6807742 B2 JP 6807742B2 JP 2016520011 A JP2016520011 A JP 2016520011A JP 2016520011 A JP2016520011 A JP 2016520011A JP 6807742 B2 JP6807742 B2 JP 6807742B2
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M13/00—Insufflators for therapeutic or disinfectant purposes, i.e. devices for blowing a gas, powder or vapour into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8218—Gas operated
- A61M2205/8225—Gas operated using incorporated gas cartridges for the driving gas
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Description
本発明は、2013年10月2日に出願された「Therapeutic Agents for Delivery Using a Catheter and Pressure Source」という名称の米国非仮特許出願第14/044,040号明細書の優先権の利益を主張し、その開示内容は、全体として参照により本明細書に組み込まれる。
Claims (10)
- 標的部位に治療薬を送達するためのシステムであって、
粉末からなる治療薬と、
前記治療薬を保持する容器と、
加圧流体を有する圧力源であって、前記容器の少なくとも一部と選択的に流体連通している圧力源と、
前記容器と流体連通し、かつ標的部位に前記治療薬を送達するようなサイズの内腔を有し、内視鏡の内腔を通して配置されて使用されるようにされたカテーテルと
を具備し、
前記治療薬の粒子の直径が、約1ミクロン〜約925ミクロンの範囲であり、
前記治療薬の前記粒子の質量が、約0.0001mg〜約0.5mgの範囲であり、
前記粒子の前記直径に対する前記カテーテルの内径の比が、4:1を超える値であり、
前記加圧流体の調節された圧力が、約0.01psi〜約100psiであり、及び
前記治療薬の粒子の重力F G 対抗力F D 比が0.001:1を超える値となるようにされ、
前記治療薬の粒子が前記標的部位にまでエアロゾル化することなく送達されるようにされた、システム。 - 前記治療薬の粒子の前記直径が、約45ミクロン〜約400ミクロンの範囲である、請求項1に記載のシステム。
- 前記治療薬の前記粒子の前記質量が、約0.0001mg〜約0.25mgの範囲である、請求項1又は2に記載のシステム。
- 前記粒子の直径に対する前記カテーテルの内径の前記比が、少なくとも7.5:1である、請求項1乃至3のいずれか一項に記載のシステム。
- 前記加圧流体の前記調節された圧力が、約0.5psi〜約75psiである、請求項1乃至4のいずれか一項に記載のシステム。
- 前記圧力源からの流体が、前記容器の第2領域に向かう方向で前記容器の第1領域を通して向けられ、前記流体は、前記容器の前記第2領域から前記容器の前記第1領域に向かう方向に、その後前記標的部位に向かって、前記治療薬を押し進めるように、少なくとも部分的に方向が変えられる、請求項1乃至5のいずれか一項に記載のシステム。
- 使用中、前記容器の前記第1領域が、前記容器の前記第2領域の垂直方向上方に配置される、請求項6に記載のシステム。
- 前記容器内に配置された入口チューブをさらに具備し、前記入口チューブが、前記容器の前記第1領域の近くに配置された第1端部と、前記容器の前記第2領域の近くに配置された第2端部とを有し、前記圧力源からの前記流体が、前記入口チューブを通って、前記第1領域から前記第2領域への方向で前記容器のリザーバ内に流れ込む、請求項7に記載のシステム。
- 前記容器のリザーバと流体連通する出口チューブをさらに具備し、前記出口チューブが前記容器内に少なくとも部分的に配置されている、請求項1乃至8のいずれか一項に記載のシステム。
- 前記加圧流体が二酸化炭素を含む、請求項1乃至9のいずれか一項に記載のシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/044,040 US9867931B2 (en) | 2013-10-02 | 2013-10-02 | Therapeutic agents for delivery using a catheter and pressure source |
US14/044,040 | 2013-10-02 | ||
PCT/US2014/058016 WO2015050814A2 (en) | 2013-10-02 | 2014-09-29 | Therapeutic agents for delivery using a catheter and pressure source |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2016538895A JP2016538895A (ja) | 2016-12-15 |
JP6807742B2 true JP6807742B2 (ja) | 2021-01-06 |
Family
ID=51795745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016520011A Active JP6807742B2 (ja) | 2013-10-02 | 2014-09-29 | カテーテルおよび圧力源を用いて送達する治療薬 |
Country Status (7)
Country | Link |
---|---|
US (4) | US9867931B2 (ja) |
EP (1) | EP3052168B1 (ja) |
JP (1) | JP6807742B2 (ja) |
CN (2) | CN105792869B (ja) |
AU (1) | AU2014329827B2 (ja) |
CA (1) | CA2925900C (ja) |
WO (1) | WO2015050814A2 (ja) |
Families Citing this family (36)
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CN101160143A (zh) | 2005-02-15 | 2008-04-09 | 弗吉尼亚大学 | 用于急性止血、治疗急性损伤和慢性溃疡的矿物技术(mt) |
US7604819B2 (en) | 2006-05-26 | 2009-10-20 | Z-Medica Corporation | Clay-based hemostatic agents and devices for the delivery thereof |
US8858969B2 (en) | 2010-09-22 | 2014-10-14 | Z-Medica, Llc | Hemostatic compositions, devices, and methods |
IN2014DN11041A (ja) | 2012-06-22 | 2015-09-25 | Z Medica Llc | |
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US9867931B2 (en) | 2013-10-02 | 2018-01-16 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
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WO2019067680A1 (en) | 2017-09-27 | 2019-04-04 | Cook Medical Technologies Llc | CROSSLINKING SUBMUCOSAL INJECTION SYSTEM |
US10786596B2 (en) | 2018-01-12 | 2020-09-29 | Boston Scientific Scimed, Inc. | Powder for achieving hemostasis |
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CN105792869A (zh) | 2016-07-20 |
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US10806853B2 (en) | 2020-10-20 |
US9867931B2 (en) | 2018-01-16 |
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US20200397983A1 (en) | 2020-12-24 |
CN105792869B (zh) | 2020-11-13 |
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US20230277764A1 (en) | 2023-09-07 |
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