JP6787899B2 - 医薬的活性化合物 - Google Patents

医薬的活性化合物 Download PDF

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JP6787899B2
JP6787899B2 JP2017533901A JP2017533901A JP6787899B2 JP 6787899 B2 JP6787899 B2 JP 6787899B2 JP 2017533901 A JP2017533901 A JP 2017533901A JP 2017533901 A JP2017533901 A JP 2017533901A JP 6787899 B2 JP6787899 B2 JP 6787899B2
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trans
phenyl
cyclohexyl
amino
acetamide
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JP2017533901A
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Japanese (ja)
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JP2018500351A (ja
JP2018500351A5 (enExample
Inventor
ジョン シールス，ジェイソン
ジョン シールス，ジェイソン
ポール ワッツ，ジョン
ポール ワッツ，ジョン
トーマス オニオンズ，スチュアート
トーマス オニオンズ，スチュアート
アブドゥル クッドゥース，モハメット
アブドゥル クッドゥース，モハメット
ウィリアム リグルワース，ジョーセフ
ウィリアム リグルワース，ジョーセフ
ピーター サムブルック‐スミス，コリン
ピーター サムブルック‐スミス，コリン
ネイラー，アラン
ロンデスボロー，デレク
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ベルゲンビオ アーエスアー
ベルゲンビオ アーエスアー
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Priority claimed from GBGB1508787.7A external-priority patent/GB201508787D0/en
Priority claimed from GBGB1519919.3A external-priority patent/GB201519919D0/en
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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