JP6757667B2 - Cd28を介したシグナル伝達を阻害する短ペプチドによる炎症性疾病の症候の軽減 - Google Patents

Cd28を介したシグナル伝達を阻害する短ペプチドによる炎症性疾病の症候の軽減 Download PDF

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JP6757667B2
JP6757667B2 JP2016536910A JP2016536910A JP6757667B2 JP 6757667 B2 JP6757667 B2 JP 6757667B2 JP 2016536910 A JP2016536910 A JP 2016536910A JP 2016536910 A JP2016536910 A JP 2016536910A JP 6757667 B2 JP6757667 B2 JP 6757667B2
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peptide
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ala
radiation
pharmaceutical composition
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JP2017501999A (ja
JP2017501999A5 (enExample
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カエンプフェール、レイモンド
シャーヴァン、アナト
アラド、ギラ
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イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド
アトックス バイオ リミテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70521CD28, CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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  • Immunology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
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  • Otolaryngology (AREA)
JP2016536910A 2013-12-06 2014-12-07 Cd28を介したシグナル伝達を阻害する短ペプチドによる炎症性疾病の症候の軽減 Expired - Fee Related JP6757667B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361912631P 2013-12-06 2013-12-06
US61/912,631 2013-12-06
US201461924869P 2014-01-08 2014-01-08
US61/924,869 2014-01-08
PCT/IL2014/051067 WO2015083173A1 (en) 2013-12-06 2014-12-07 Reduction of inflammatory disease symptoms by short peptides that inhibit signaling through cd28

Publications (3)

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JP2017501999A JP2017501999A (ja) 2017-01-19
JP2017501999A5 JP2017501999A5 (enExample) 2017-12-28
JP6757667B2 true JP6757667B2 (ja) 2020-09-23

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JP2016536910A Expired - Fee Related JP6757667B2 (ja) 2013-12-06 2014-12-07 Cd28を介したシグナル伝達を阻害する短ペプチドによる炎症性疾病の症候の軽減

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US (2) US9963497B2 (enExample)
EP (1) EP3077415B1 (enExample)
JP (1) JP6757667B2 (enExample)
AU (2) AU2014358677A1 (enExample)
CA (1) CA2932150A1 (enExample)
SG (2) SG10201804750XA (enExample)
WO (1) WO2015083173A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6757667B2 (ja) * 2013-12-06 2020-09-23 イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド Cd28を介したシグナル伝達を阻害する短ペプチドによる炎症性疾病の症候の軽減
CA3060443A1 (en) 2017-04-19 2018-10-25 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors
CN111163792A (zh) * 2017-10-06 2020-05-15 耶路撒冷希伯来大学伊森姆研究发展有限公司 用于治疗病毒感染的肽
JP7273421B2 (ja) 2018-02-21 2023-05-15 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用
CN111253469B (zh) * 2020-03-06 2021-09-07 暨南大学 一种自组装短肽及其在治疗痤疮方面的应用
US20250134947A1 (en) * 2021-11-02 2025-05-01 Enumita As Tri-, tetra and pentapeptides, compositions thereof and their use in the therapy of psoriasis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8535672B2 (en) * 2002-04-04 2013-09-17 Yissum Research Development Of The Hebrew University Of Jerusalem Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between CD28 and the superantigen and uses thereof
WO2004087754A1 (en) 2003-04-03 2004-10-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
US20110097339A1 (en) * 2008-07-18 2011-04-28 Domantis Limited Compositions monovalent for CD28 binding and methods of use
ES2896149T3 (es) * 2010-02-18 2022-02-24 Ose Immunotherapeutics Anticuerpos humanizados anti-CD28
DE102012008730A1 (de) 2011-12-02 2013-06-06 Dr. Budz GmbH Orale Zusammensetzungen mit ungesättigten C18-Fettsäuren und ihre Verwendung
RU2014133530A (ru) 2012-01-16 2016-03-20 Эйтокс Байо Лтд. Синтетические пептиды для лечения бактериальных инфекций
JP6757667B2 (ja) * 2013-12-06 2020-09-23 イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド Cd28を介したシグナル伝達を阻害する短ペプチドによる炎症性疾病の症候の軽減

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Publication number Publication date
AU2017261479B2 (en) 2019-05-02
US9963497B2 (en) 2018-05-08
AU2014358677A1 (en) 2016-06-02
AU2017261479A1 (en) 2017-11-30
US20180215804A1 (en) 2018-08-02
EP3077415A1 (en) 2016-10-12
US10280209B2 (en) 2019-05-07
CA2932150A1 (en) 2015-06-11
WO2015083173A1 (en) 2015-06-11
SG11201604512XA (en) 2016-07-28
US20160289295A1 (en) 2016-10-06
JP2017501999A (ja) 2017-01-19
SG10201804750XA (en) 2018-07-30
EP3077415B1 (en) 2020-02-12

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