JP6747981B2 - 腫瘍抗原発現組換えポックスウイルス及び免疫チェックポイント分子アンタゴニストまたはアゴニストを用いた癌治療のための併用療法 - Google Patents

腫瘍抗原発現組換えポックスウイルス及び免疫チェックポイント分子アンタゴニストまたはアゴニストを用いた癌治療のための併用療法 Download PDF

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JP6747981B2
JP6747981B2 JP2016567370A JP2016567370A JP6747981B2 JP 6747981 B2 JP6747981 B2 JP 6747981B2 JP 2016567370 A JP2016567370 A JP 2016567370A JP 2016567370 A JP2016567370 A JP 2016567370A JP 6747981 B2 JP6747981 B2 JP 6747981B2
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cancer
immune checkpoint
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フォイ・スーザン
マンドル・ステファニー
ラウントリー・リャン
フランツソフ・アレックス
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バヴァリアン・ノルディック・アクティーゼルスカブ
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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JP2016567370A 2014-05-13 2015-05-08 腫瘍抗原発現組換えポックスウイルス及び免疫チェックポイント分子アンタゴニストまたはアゴニストを用いた癌治療のための併用療法 Active JP6747981B2 (ja)

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US201461992788P 2014-05-13 2014-05-13
US61/992,788 2014-05-13
PCT/US2015/029855 WO2015175334A2 (en) 2014-05-13 2015-05-08 Combination therapy for treating cancer with a recombinant poxvirus expressing a tumor antigen and an immune checkpoint molecule antagonist or agonist

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JP2017515837A JP2017515837A (ja) 2017-06-15
JP2017515837A5 JP2017515837A5 (enExample) 2018-06-14
JP6747981B2 true JP6747981B2 (ja) 2020-08-26

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US (1) US20170266270A1 (enExample)
EP (1) EP3142690B1 (enExample)
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KR (1) KR102499737B1 (enExample)
CN (1) CN106456747A (enExample)
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CA (1) CA2946418C (enExample)
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CN107847534B (zh) 2015-04-17 2022-10-04 纪念斯隆凯特琳癌症中心 Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用
CA2991976A1 (en) 2015-07-13 2017-01-19 Cytomx Therapeutics, Inc. Anti-pd-1 antibodies, activatable anti-pd-1 antibodies, and methods of use thereof
US10512662B2 (en) 2016-02-25 2019-12-24 Memorial Sloan Kettering Cancer Center Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human Flt3L or GM-CSF for cancer immunotherapy
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SG11201808058PA (en) * 2016-03-18 2018-10-30 Nantcell Inc Multimodal vector for dendritic cell infection
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CN107281474A (zh) * 2016-04-11 2017-10-24 中国科学院上海巴斯德研究所 增强抗肿瘤免疫反应的新型免疫策略和免疫组合物
HUE065176T2 (hu) 2016-06-02 2024-05-28 Ultimovacs Asa Vakcina kombinációban immunellenõrzõpont inhibitorral felhasználásra rák kezelésében
RS62589B1 (sr) * 2016-11-02 2021-12-31 Jounce Therapeutics Inc Antitela na pd-1 i njihova upotreba
KR200486872Y1 (ko) 2016-11-16 2018-07-10 김영선 가변형 조립식 책상
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CN113056284A (zh) * 2018-11-20 2021-06-29 巴法里安诺迪克有限公司 通过肿瘤内和/或静脉内施用编码4-1bbl(cd137l)和/或cd40l的重组mva治疗癌症的疗法
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
EP3941514A4 (en) * 2019-03-20 2023-08-30 Turnstone Biologics Inc. ONCOLYTIC VIROTHERAPY BY HETEROLOGY SEQUENTIAL BOOSTER
AU2020350137A1 (en) 2019-09-20 2022-04-28 Merck Patent Gmbh Combination of a poxvirus encoding HPV polypeptides and IL-2 with an anti-PD-L1 antibody
CN114980920A (zh) 2019-11-18 2022-08-30 詹森生物科技公司 基于突变体calr和jak2的疫苗及其用途
US20230059344A1 (en) * 2019-11-20 2023-02-23 Bavarian Nordic A/S Medical Uses of 4-1BBL Adjuvanted Recombinant Modified Vaccinia Virus Ankara (MVA)
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IL248507A0 (en) 2016-12-29
WO2015175334A2 (en) 2015-11-19
AU2015259510A1 (en) 2016-11-10
US20170266270A1 (en) 2017-09-21
RU2724433C2 (ru) 2020-06-23
CA2946418C (en) 2023-07-04
EP3142690A2 (en) 2017-03-22
DK3142690T3 (da) 2022-05-09
NZ725459A (en) 2023-04-28
RU2016148311A3 (enExample) 2018-12-26
AU2015259510B2 (en) 2020-10-01
KR102499737B1 (ko) 2023-02-13
EP3142690B1 (en) 2022-02-23
CA2946418A1 (en) 2015-11-19
JP2017515837A (ja) 2017-06-15
IL248507B (en) 2022-07-01
ES2913236T3 (es) 2022-06-01
CN106456747A (zh) 2017-02-22
WO2015175334A3 (en) 2016-02-04
KR20170003556A (ko) 2017-01-09
RU2016148311A (ru) 2018-06-18

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