JP6660877B2 - アミロイド−β−結合性ペプチド、ならびにアルツハイマー型認知症の治療および診断のためのその使用 - Google Patents
アミロイド−β−結合性ペプチド、ならびにアルツハイマー型認知症の治療および診断のためのその使用 Download PDFInfo
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- JP6660877B2 JP6660877B2 JP2016517288A JP2016517288A JP6660877B2 JP 6660877 B2 JP6660877 B2 JP 6660877B2 JP 2016517288 A JP2016517288 A JP 2016517288A JP 2016517288 A JP2016517288 A JP 2016517288A JP 6660877 B2 JP6660877 B2 JP 6660877B2
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102013016002.2A DE102013016002A1 (de) | 2013-09-26 | 2013-09-26 | Zyklische, Amyloid-Beta-bindende Peptide und deren Verwendung |
| DE102013016002.2 | 2013-09-26 | ||
| DE102014003262.0 | 2014-03-12 | ||
| DE102014003262.0A DE102014003262A1 (de) | 2014-03-12 | 2014-03-12 | Amyloid-Beta-bindende Peptide und deren Verwendung für die Therapie und die Diagnose der Alzheimerschen Demenz |
| PCT/DE2014/000477 WO2015043567A1 (de) | 2013-09-26 | 2014-09-23 | Amyloid-beta-bindende peptide und deren verwendung für die therapie und die diagnose der alzheimerschen demenz |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539911A JP2016539911A (ja) | 2016-12-22 |
| JP2016539911A5 JP2016539911A5 (enExample) | 2018-12-27 |
| JP6660877B2 true JP6660877B2 (ja) | 2020-03-11 |
Family
ID=51932152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016517288A Active JP6660877B2 (ja) | 2013-09-26 | 2014-09-23 | アミロイド−β−結合性ペプチド、ならびにアルツハイマー型認知症の治療および診断のためのその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10995118B2 (enExample) |
| EP (2) | EP3049099B1 (enExample) |
| JP (1) | JP6660877B2 (enExample) |
| CN (1) | CN105745219B (enExample) |
| DK (1) | DK3049099T3 (enExample) |
| ES (2) | ES2953883T3 (enExample) |
| WO (1) | WO2015043567A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102016125645A1 (de) | 2016-12-23 | 2018-06-28 | Forschungszentrum Jülich GmbH | D-enantiomere Peptide zur Therapie von chronischem und neuropathischem Schmerz |
| CN106866792B (zh) * | 2017-02-24 | 2020-09-04 | 中山大学 | 一类环十肽分子及其应用 |
| DE102017010842A1 (de) * | 2017-11-23 | 2019-05-23 | Forschungszentrum Jülich GmbH | Verfahren zur Quantifizierung von Proteinaggregaten einer Proteinfehlfaltungserkrankung in einer Probe |
| DE102021121435A1 (de) | 2021-08-18 | 2023-02-23 | Priavoid Gmbh | Aß-BINDENDE SUBSTANZEN |
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| CA2214247C (en) | 1995-03-14 | 2004-02-10 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
| US7384910B2 (en) * | 1997-10-08 | 2008-06-10 | Castillo Gerardo M | Small peptides for the treatment of Alzheimer's disease and other beta-amyloid protein fibrillogenesis disorders |
| DE69930164T2 (de) | 1998-12-18 | 2006-11-23 | The Penn State Research Foundation | Intein-vermittelte cyclisierung von peptiden |
| EA004739B1 (ru) * | 1999-11-05 | 2004-08-26 | Эксоникс, Инк. | ПЕПТИДНЫЕ АНАЛОГИ И МИМЕТИКИ, ПОДХОДЯЩИЕ ДЛЯ ПРИМЕНЕНИЯ IN VIVO ПРИ ЛЕЧЕНИИ ЗАБОЛЕВАНИЙ, СВЯЗАННЫХ С АНОМАЛЬНОЙ УКЛАДКОЙ БЕЛКОВ В АМИЛОИДНЫЕ ИЛИ АМИЛОИДПОДОБНЫЕ ОТЛОЖЕНИЯ, ИЛИ ИХ ПАТОЛОГИЧЕСКИЕ ПРЕДШЕСТВЕННИКИ, ОБОГАЩЕННЫЕ b-СКЛАДКАМИ |
| AU1608801A (en) | 1999-11-15 | 2001-05-30 | Parker Hughes Institute | Diamino platinum (ii) antitumor complexes |
| DE10117281A1 (de) | 2001-04-06 | 2002-10-24 | Inst Molekulare Biotechnologie | Peptid zur Diagnose und Therapie der Alzheimer-Demenz |
| CA2530927A1 (en) * | 2003-06-30 | 2005-01-06 | Tel Aviv University Future Technology Development L.P. | Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases |
| GB0503434D0 (en) * | 2005-02-18 | 2005-03-30 | Senexis Ltd | Amyloid-binding peptides, analogues and uses thereof |
| DE102005049537B4 (de) | 2005-10-17 | 2010-04-22 | Forschungszentrum Karlsruhe Gmbh | Verfahren zur Herstellung zyklischer Peptide und Verwendung der derart hergestellten zyklischen Peptide |
| DE102006015140A1 (de) | 2006-03-31 | 2007-10-11 | Philipps-Universität Marburg | Heterozyklische Verbindungen mit Wirkung gegen neurodegenerative Erkrankungen |
| WO2007145589A1 (en) * | 2006-06-15 | 2007-12-21 | Per Arvidsson | Peptides that are capable of binding to amyloid-beta peptide. |
| EP2139524A1 (en) | 2007-03-23 | 2010-01-06 | The Governors of the University of Alberta | Multivalent heterobifunctional polymers and methods of their use |
| DE102008037564A1 (de) * | 2008-11-19 | 2010-05-20 | Forschungszentrum Jülich GmbH | Zusammensetzung zur Herstellung von anti-Amyloid beta-Peptid-Antikörpern mit D-Peptiden |
| DE102010019336A1 (de) | 2010-05-05 | 2011-11-10 | Forschungszentrum Jülich GmbH | Mittel zur Behandlung der Alzheimerschen Demenz |
| DE102010017130B4 (de) | 2010-05-28 | 2018-11-29 | Forschungszentrum Jülich GmbH | Hybrid-Verbindung, deren Verwendung und Verfahren zu deren Herstellung |
| WO2013021353A1 (en) | 2011-08-11 | 2013-02-14 | Bar-Ilan University | Surface modified proteinaceous spherical particles and uses thereof |
| CN104380111B (zh) | 2012-04-05 | 2017-08-29 | 于利希研究中心有限公司 | 包含多价结合淀粉样β蛋白的D‑肽的聚合物及其应用 |
| DE102012102998B4 (de) | 2012-04-05 | 2013-12-05 | Forschungszentrum Jülich GmbH | Polymere, enthaltend multivalente Amyloid-Beta-bindende D-Peptide und deren Verwendung |
| JP2015518474A (ja) * | 2012-04-05 | 2015-07-02 | フォルシュングスツェントルム ユーリッヒ ゲゼルシャフト ミット ベシュレンクテル ハフツングＦｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ Ｊｕｅｌｉｃｈ ＧｍｂＨ | 血液、血液生産物及び器官を処置する方法 |
| DE102012102999A1 (de) | 2012-04-05 | 2013-10-10 | Forschungszentrum Jülich GmbH | Verfahren zur Behandlung von Blut, Blutprodukten und Organen |
| DK2991664T3 (da) * | 2013-04-30 | 2019-12-02 | Forschungszentrum Juelich Gmbh | Midler til forebyggelse og behandling af følgesygdomme af HIV og andre virusinfektioner |
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| CN105745219A (zh) | 2016-07-06 |
| JP2016539911A (ja) | 2016-12-22 |
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| EP3747454C0 (de) | 2023-06-07 |
| EP3747454A1 (de) | 2020-12-09 |
| US11274125B2 (en) | 2022-03-15 |
| EP3747454B9 (de) | 2023-10-04 |
| WO2015043567A1 (de) | 2015-04-02 |
| US20200317734A1 (en) | 2020-10-08 |
| DK3049099T3 (da) | 2020-09-21 |
| EP3747454B1 (de) | 2023-06-07 |
| US10995118B2 (en) | 2021-05-04 |
| ES2818929T3 (es) | 2021-04-14 |
| US20160297852A1 (en) | 2016-10-13 |
| US20200002379A9 (en) | 2020-01-02 |
| EP3049099B1 (de) | 2020-06-17 |
| CN105745219B (zh) | 2020-10-09 |
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