JP6649271B2 - コンタクトレンズおよび眼内レンズのための(メタ)アクリルアミドポリマー - Google Patents

コンタクトレンズおよび眼内レンズのための(メタ)アクリルアミドポリマー Download PDF

Info

Publication number
JP6649271B2
JP6649271B2 JP2016563083A JP2016563083A JP6649271B2 JP 6649271 B2 JP6649271 B2 JP 6649271B2 JP 2016563083 A JP2016563083 A JP 2016563083A JP 2016563083 A JP2016563083 A JP 2016563083A JP 6649271 B2 JP6649271 B2 JP 6649271B2
Authority
JP
Japan
Prior art keywords
polymer
acrylamide
meth
iol
contact lens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016563083A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017513596A (ja
JP2017513596A5 (enExample
Inventor
パトリック エイチ. ベンズ
パトリック エイチ. ベンズ
アダム ルブール
アダム ルブール
Original Assignee
ベンズ リサーチ アンド ディベロップメント コーポレーション
ベンズ リサーチ アンド ディベロップメント コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ベンズ リサーチ アンド ディベロップメント コーポレーション, ベンズ リサーチ アンド ディベロップメント コーポレーション filed Critical ベンズ リサーチ アンド ディベロップメント コーポレーション
Publication of JP2017513596A publication Critical patent/JP2017513596A/ja
Publication of JP2017513596A5 publication Critical patent/JP2017513596A5/ja
Application granted granted Critical
Publication of JP6649271B2 publication Critical patent/JP6649271B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/24Homopolymers or copolymers of amides or imides
    • C08L33/26Homopolymers or copolymers of acrylamide or methacrylamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52Amides or imides
    • C08F20/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52Amides or imides
    • C08F20/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F20/56Acrylamide; Methacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52Amides or imides
    • C08F20/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F20/58Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-acryloylmorpholine
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/58Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/16Nitrogen-containing compounds
    • C08K5/22Compounds containing nitrogen bound to another nitrogen atom
    • C08K5/23Azo-compounds
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/02Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04Contact lenses for the eyes
    • G02C7/049Contact lenses having special fitting or structural features achieved by special materials or material structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/16Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Eyeglasses (AREA)
JP2016563083A 2014-04-18 2015-04-17 コンタクトレンズおよび眼内レンズのための(メタ)アクリルアミドポリマー Active JP6649271B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461981684P 2014-04-18 2014-04-18
US61/981,684 2014-04-18
PCT/US2015/026371 WO2015161199A1 (en) 2014-04-18 2015-04-17 (meth)acrylamide polymers for contact lens and intraocular lens

Publications (3)

Publication Number Publication Date
JP2017513596A JP2017513596A (ja) 2017-06-01
JP2017513596A5 JP2017513596A5 (enExample) 2018-06-07
JP6649271B2 true JP6649271B2 (ja) 2020-02-19

Family

ID=53015964

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016563083A Active JP6649271B2 (ja) 2014-04-18 2015-04-17 コンタクトレンズおよび眼内レンズのための(メタ)アクリルアミドポリマー

Country Status (12)

Country Link
US (1) US10371864B2 (enExample)
EP (2) EP4241797A3 (enExample)
JP (1) JP6649271B2 (enExample)
KR (1) KR102295439B1 (enExample)
CN (1) CN106456830B (enExample)
AU (1) AU2015247438B2 (enExample)
BR (1) BR112016024192B1 (enExample)
CA (1) CA2945961C (enExample)
IL (1) IL248382B (enExample)
MX (1) MX380510B (enExample)
TW (1) TWI665221B (enExample)
WO (1) WO2015161199A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2989690A1 (en) 2015-06-17 2016-12-22 Clariant International Ltd Water-soluble or water-swellable polymers as water loss reducers in cement slurries
US10196470B2 (en) * 2016-05-16 2019-02-05 Benz Research And Development Corp. Hydrophobic intraocular lens
FR3051792B1 (fr) 2016-05-30 2020-01-24 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris Nouveaux composes, derives de dioxoborolane ou de dioxaborinane fonctionnalises, leur procede de preparation et leurs utilisations
JP7032402B2 (ja) 2016-12-12 2022-03-08 クラリアント・インターナシヨナル・リミテツド ある特定のレベルのバイオベース炭素を含むポリマー
US11311473B2 (en) 2016-12-12 2022-04-26 Clariant International Ltd Use of a bio-based polymer in a cosmetic, dermatological or pharmaceutical composition
EP3554643B1 (en) 2016-12-15 2025-03-19 Clariant International Ltd Water-soluble and/or water-swellable hybrid polymer
ES3017507T3 (en) 2016-12-15 2025-05-13 Clariant Int Ltd Water-soluble and/or water-swellable hybrid polymer
EP3554644B1 (en) 2016-12-15 2025-03-19 Clariant International Ltd Water-soluble and/or water-swellable hybrid polymer
WO2018108667A1 (en) 2016-12-15 2018-06-21 Clariant International Ltd Water-soluble and/or water-swellable hybrid polymer
US10894111B2 (en) * 2016-12-16 2021-01-19 Benz Research And Development Corp. High refractive index hydrophilic materials
JP2020519402A (ja) 2017-05-16 2020-07-02 ベンズ リサーチ アンド デベロップメント コーポレイションBenz Research And Development Corp. 微量注入可能な低色収差眼内レンズ材料
TW202604566A (zh) 2020-04-17 2026-02-01 小利蘭史丹佛大學董事會 用於生物醫藥調配物之聚合物賦形劑
WO2023230078A1 (en) * 2022-05-23 2023-11-30 The Board Of Trustees Of The Leland Stanford Junior University Antibody biopharmaceutical formulations including polymer excipients

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338419A (en) * 1979-02-09 1982-07-06 Syntex (U.S.A.) Inc. Process for treatment of hydrogel lens with thiols
DE3545595A1 (de) 1985-12-21 1987-06-25 Behringwerke Ag Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung
AU3078992A (en) * 1992-12-04 1994-07-04 958075 Ontario Inc. A method for the production of a soft contact lens
US5256751A (en) * 1993-02-08 1993-10-26 Vistakon, Inc. Ophthalmic lens polymer incorporating acyclic monomer
US5532289A (en) 1995-04-14 1996-07-02 Benz Research And Development Corp. Contact lens having improved dimensional stability
US6011081A (en) 1995-04-14 2000-01-04 Benz Research And Development Corp. Contact lens having improved dimensional stability
JP2001206912A (ja) * 2000-01-25 2001-07-31 Oji Paper Co Ltd 活性エネルギー線硬化重合体及びそれを用いたインクジェット記録シート
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US7270678B2 (en) * 2002-06-28 2007-09-18 Bausch & Lomb Incorporated Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
EP1584663A4 (en) * 2002-12-26 2006-08-02 Mitsui Chemicals Inc AGING PROTECTION MATERIAL WITH HYDROXYL GROUP-CONTAINING ACRYLAMIDE DERIVATIVE AND USE THEREOF
JP4536369B2 (ja) * 2002-12-26 2010-09-01 三井化学株式会社 水酸基含有アクリルアミド誘導体を用いる防汚材料
US7905917B2 (en) 2003-03-31 2011-03-15 Bausch & Lomb Incorporated Aspheric lenses and lens family
US7214809B2 (en) * 2004-02-11 2007-05-08 Johnson & Johnson Vision Care, Inc. (Meth)acrylamide monomers containing hydroxy and silicone functionalities
US20110166247A1 (en) * 2006-12-07 2011-07-07 David Myung Interpenetrating polymer network hydrogel contact lenses
JP5390409B2 (ja) 2007-03-05 2014-01-15 ベンズ リサーチ アンド ディベロップメント コーポレーション 天然発色団およびその誘導体を含む光フィルター
EP2203490A1 (en) 2007-10-10 2010-07-07 Benz Research and Development Corporation Hydrogel with high water content and stability
US20100280147A1 (en) * 2008-02-15 2010-11-04 Laura Hartmann High refractive index interpenetrating networks for ophthalmic applications
CN102227207B (zh) * 2008-10-07 2013-07-10 狮王株式会社 毛发化妆料
US9384308B2 (en) 2010-01-05 2016-07-05 Bentley Systems, Inc. Multi-dimensional artifact assemblage for infrastructure and other assets with interface node mediators
JP5720103B2 (ja) * 2010-03-18 2015-05-20 東レ株式会社 シリコーンハイドロゲル、眼用レンズおよびコンタクトレンズ
RU2576622C2 (ru) * 2010-07-30 2016-03-10 Новартис Аг Амфифильные полисилоксановые преполимеры и их применение
US9170349B2 (en) * 2011-05-04 2015-10-27 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
MX365605B (es) 2011-09-16 2019-06-07 Benz Res And Development Corp Materiales absorbentes de luz ultravioleta para lente intraocular y uso de los mismos.
BR112014006188B1 (pt) 2011-09-16 2021-06-08 Benz Research And Development Corp. lente intraocular, composição e metodo para preparar uma composição
US9588258B2 (en) * 2011-12-23 2017-03-07 Johnson & Johnson Vision Care, Inc. Silicone hydrogels formed from zero diluent reactive mixtures
CN102617787B (zh) * 2012-03-21 2014-07-09 东南大学 一种水凝胶接触镜
US9297929B2 (en) * 2012-05-25 2016-03-29 Johnson & Johnson Vision Care, Inc. Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers
TWI582118B (zh) 2012-05-25 2017-05-11 壯生和壯生視覺關懷公司 含水溶性n-(2羥烷基)(甲基)丙烯醯胺聚合物或共聚物之隱形眼鏡
JP6163543B2 (ja) * 2012-05-25 2017-07-12 ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated 完全に重合したuvブロック性シリコーンハイドロゲルレンズ

Also Published As

Publication number Publication date
TWI665221B (zh) 2019-07-11
MX380510B (es) 2025-03-12
US10371864B2 (en) 2019-08-06
IL248382A0 (en) 2016-11-30
TW201546099A (zh) 2015-12-16
JP2017513596A (ja) 2017-06-01
EP4241797A3 (en) 2023-10-11
CA2945961C (en) 2022-08-16
US20170038500A1 (en) 2017-02-09
AU2015247438B2 (en) 2020-04-02
EP4241797A2 (en) 2023-09-13
AU2015247438A1 (en) 2016-11-03
IL248382B (en) 2022-04-01
KR20160149209A (ko) 2016-12-27
CN106456830A (zh) 2017-02-22
BR112016024192A2 (pt) 2018-06-26
WO2015161199A1 (en) 2015-10-22
BR112016024192B1 (pt) 2022-08-16
KR102295439B1 (ko) 2021-08-27
CA2945961A1 (en) 2015-10-22
CN106456830B (zh) 2020-11-03
EP3132292A1 (en) 2017-02-22
MX2016013620A (es) 2017-06-08

Similar Documents

Publication Publication Date Title
KR102295439B1 (ko) 콘택트 렌즈 및 안내 렌즈용 (메트)아크릴아미드 중합체
AU2016204924B2 (en) Hydrophobic intraocular lens
EP3555677B1 (en) High refractive index hydrophilic materials
JP5363683B2 (ja) グリスニングが低い、高屈折率の眼科的アクリルデバイス材料
ES2703566T3 (es) Envasado en húmedo de materiales de lente intraocular con elevado índice refractivo
CN105793303B (zh) 软质疏水性丙烯酸材料
KR20150143634A (ko) 개방부 및 동심 환형 구역을 갖는 파킥 렌즈
ES2326706T3 (es) Materiales para dispositivos oftalmicos de alto indice de refraccion.
JP2019056086A (ja) ゲル組成物
JP2015512665A (ja) マルチアームpegマクロマーを含む眼科用および耳鼻咽喉科用デバイス材料
US12226545B2 (en) Micro injectable, low chromatic aberration intraocular lens materials
HK1229267B (zh) 用於隐形眼镜和人工晶状体的(甲基)丙烯酰胺聚合物
JP7859323B2 (ja) 眼科デバイス用改質剤
HK1229267A1 (en) (meth)acrylamide polymers for contact lens and intraocular lens
US20240117094A1 (en) Modifier for ophthalmological device
BR112019024078B1 (pt) Lente intraocular, composição e método para fabricar uma lente intraocular compreendendo pelo menos um copolímero compreendendo subunidades monoméricas

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180417

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180417

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20181227

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190220

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20190514

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190819

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20191218

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20200116

R150 Certificate of patent or registration of utility model

Ref document number: 6649271

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250