CA2945961C - (meth)acrylamide polymers for contact lens and intraocular lens - Google Patents

(meth)acrylamide polymers for contact lens and intraocular lens Download PDF

Info

Publication number
CA2945961C
CA2945961C CA2945961A CA2945961A CA2945961C CA 2945961 C CA2945961 C CA 2945961C CA 2945961 A CA2945961 A CA 2945961A CA 2945961 A CA2945961 A CA 2945961A CA 2945961 C CA2945961 C CA 2945961C
Authority
CA
Canada
Prior art keywords
acrylamide
contact lens
meth
iol
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2945961A
Other languages
English (en)
French (fr)
Other versions
CA2945961A1 (en
Inventor
Patrick H. Benz
Adam REBOUL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Benz Research and Development Corp
Original Assignee
Benz Research and Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benz Research and Development Corp filed Critical Benz Research and Development Corp
Publication of CA2945961A1 publication Critical patent/CA2945961A1/en
Application granted granted Critical
Publication of CA2945961C publication Critical patent/CA2945961C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F20/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F20/58—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-acryloylmorpholine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/58—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/16—Nitrogen-containing compounds
    • C08K5/22—Compounds containing nitrogen bound to another nitrogen atom
    • C08K5/23—Azo-compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/24—Homopolymers or copolymers of amides or imides
    • C08L33/26—Homopolymers or copolymers of acrylamide or methacrylamide
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Eyeglasses (AREA)
CA2945961A 2014-04-18 2015-04-17 (meth)acrylamide polymers for contact lens and intraocular lens Active CA2945961C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461981684P 2014-04-18 2014-04-18
US61/981,684 2014-04-18
PCT/US2015/026371 WO2015161199A1 (en) 2014-04-18 2015-04-17 (meth)acrylamide polymers for contact lens and intraocular lens

Publications (2)

Publication Number Publication Date
CA2945961A1 CA2945961A1 (en) 2015-10-22
CA2945961C true CA2945961C (en) 2022-08-16

Family

ID=53015964

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2945961A Active CA2945961C (en) 2014-04-18 2015-04-17 (meth)acrylamide polymers for contact lens and intraocular lens

Country Status (12)

Country Link
US (1) US10371864B2 (enExample)
EP (2) EP3132292A1 (enExample)
JP (1) JP6649271B2 (enExample)
KR (1) KR102295439B1 (enExample)
CN (1) CN106456830B (enExample)
AU (1) AU2015247438B2 (enExample)
BR (1) BR112016024192B1 (enExample)
CA (1) CA2945961C (enExample)
IL (1) IL248382B (enExample)
MX (1) MX380510B (enExample)
TW (1) TWI665221B (enExample)
WO (1) WO2015161199A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107771191B (zh) 2015-06-17 2020-08-28 科莱恩国际有限公司 作为水泥浆中的降失水剂的水溶性或水溶胀性聚合物
US10196470B2 (en) 2016-05-16 2019-02-05 Benz Research And Development Corp. Hydrophobic intraocular lens
FR3051792B1 (fr) 2016-05-30 2020-01-24 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris Nouveaux composes, derives de dioxoborolane ou de dioxaborinane fonctionnalises, leur procede de preparation et leurs utilisations
US11384186B2 (en) 2016-12-12 2022-07-12 Clariant International Ltd Polymer comprising certain level of bio-based carbon
US11311473B2 (en) 2016-12-12 2022-04-26 Clariant International Ltd Use of a bio-based polymer in a cosmetic, dermatological or pharmaceutical composition
EP3554643B1 (en) 2016-12-15 2025-03-19 Clariant International Ltd Water-soluble and/or water-swellable hybrid polymer
US11339241B2 (en) 2016-12-15 2022-05-24 Clariant International Ltd. Water-soluble and/or water-swellable hybrid polymer
ES3017507T3 (en) 2016-12-15 2025-05-13 Clariant Int Ltd Water-soluble and/or water-swellable hybrid polymer
US11542343B2 (en) 2016-12-15 2023-01-03 Clariant International Ltd Water-soluble and/or water-swellable hybrid polymer
US10894111B2 (en) 2016-12-16 2021-01-19 Benz Research And Development Corp. High refractive index hydrophilic materials
CA3063611A1 (en) 2017-05-16 2018-11-22 Benz Research And Development Corp. Micro injectable, low chromatic aberration intraocular lens materials
TWI899211B (zh) * 2020-04-17 2025-10-01 小利蘭史丹佛大學董事會 用於生物醫藥調配物之聚合物賦形劑
TW202410920A (zh) 2022-05-23 2024-03-16 小利蘭史丹佛大學董事會 包括聚合物賦形劑之抗體生物醫藥調配物

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338419A (en) * 1979-02-09 1982-07-06 Syntex (U.S.A.) Inc. Process for treatment of hydrogel lens with thiols
DE3545595A1 (de) 1985-12-21 1987-06-25 Behringwerke Ag Dispersionspolymere, verfahren zu ihrer herstellung und ihre verwendung
WO1994013717A1 (en) * 1992-12-04 1994-06-23 958075 Ontario Inc. Carrying On Business As Eurocan Ventures A method for the production of a soft contact lens
US5256751A (en) * 1993-02-08 1993-10-26 Vistakon, Inc. Ophthalmic lens polymer incorporating acyclic monomer
US5532289A (en) 1995-04-14 1996-07-02 Benz Research And Development Corp. Contact lens having improved dimensional stability
US6011081A (en) 1995-04-14 2000-01-04 Benz Research And Development Corp. Contact lens having improved dimensional stability
JP2001206912A (ja) * 2000-01-25 2001-07-31 Oji Paper Co Ltd 活性エネルギー線硬化重合体及びそれを用いたインクジェット記録シート
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US7270678B2 (en) * 2002-06-28 2007-09-18 Bausch & Lomb Incorporated Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
JP4536369B2 (ja) * 2002-12-26 2010-09-01 三井化学株式会社 水酸基含有アクリルアミド誘導体を用いる防汚材料
WO2004058900A1 (ja) * 2002-12-26 2004-07-15 Mitsui Chemicals, Inc. 水酸基含有アクリルアミド誘導体を用いる防汚材料およびその用途
US7905917B2 (en) 2003-03-31 2011-03-15 Bausch & Lomb Incorporated Aspheric lenses and lens family
US7214809B2 (en) * 2004-02-11 2007-05-08 Johnson & Johnson Vision Care, Inc. (Meth)acrylamide monomers containing hydroxy and silicone functionalities
US20110166247A1 (en) * 2006-12-07 2011-07-07 David Myung Interpenetrating polymer network hydrogel contact lenses
KR101520112B1 (ko) 2007-03-05 2015-05-13 벤즈리써치앤드디벨롭먼트코오포레이숀 천연 발생 발색단 및 그의 유도체를 포함하는 광 필터
CA2702096A1 (en) 2007-10-10 2009-04-16 Benz Research And Development Corp. Hydrogel with high water content and stability
US20100280147A1 (en) * 2008-02-15 2010-11-04 Laura Hartmann High refractive index interpenetrating networks for ophthalmic applications
WO2010041530A1 (ja) * 2008-10-07 2010-04-15 ライオン株式会社 毛髪化粧料
US9384308B2 (en) 2010-01-05 2016-07-05 Bentley Systems, Inc. Multi-dimensional artifact assemblage for infrastructure and other assets with interface node mediators
JP5720103B2 (ja) * 2010-03-18 2015-05-20 東レ株式会社 シリコーンハイドロゲル、眼用レンズおよびコンタクトレンズ
BR112013002154A2 (pt) * 2010-07-30 2016-05-31 Novartis Ag pré-polímeros anfifílicos de polissiloxano e seus usos
US9170349B2 (en) * 2011-05-04 2015-10-27 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
US9381080B2 (en) 2011-09-16 2016-07-05 Benz Research And Development Corp. Hydrophobic intraocular lens
TWI583363B (zh) 2011-09-16 2017-05-21 班茲研發公司 用於眼內透鏡之紫外光吸收材料及其用途
US9588258B2 (en) * 2011-12-23 2017-03-07 Johnson & Johnson Vision Care, Inc. Silicone hydrogels formed from zero diluent reactive mixtures
CN102617787B (zh) * 2012-03-21 2014-07-09 东南大学 一种水凝胶接触镜
US9297929B2 (en) * 2012-05-25 2016-03-29 Johnson & Johnson Vision Care, Inc. Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers
HUE030467T2 (en) * 2012-05-25 2017-05-29 Bausch & Lomb Fully polymerized, UV-blocking silicone hydrogel lens
EP2855547A2 (en) * 2012-05-25 2015-04-08 Johnson & Johnson Vision Care Inc. Polymers and nanogel materials and methods for making and using the same

Also Published As

Publication number Publication date
JP6649271B2 (ja) 2020-02-19
EP4241797A3 (en) 2023-10-11
TW201546099A (zh) 2015-12-16
JP2017513596A (ja) 2017-06-01
EP3132292A1 (en) 2017-02-22
MX2016013620A (es) 2017-06-08
US20170038500A1 (en) 2017-02-09
CN106456830A (zh) 2017-02-22
US10371864B2 (en) 2019-08-06
BR112016024192A2 (pt) 2018-06-26
CN106456830B (zh) 2020-11-03
IL248382A0 (en) 2016-11-30
MX380510B (es) 2025-03-12
WO2015161199A1 (en) 2015-10-22
KR20160149209A (ko) 2016-12-27
KR102295439B1 (ko) 2021-08-27
TWI665221B (zh) 2019-07-11
EP4241797A2 (en) 2023-09-13
IL248382B (en) 2022-04-01
CA2945961A1 (en) 2015-10-22
AU2015247438B2 (en) 2020-04-02
AU2015247438A1 (en) 2016-11-03
BR112016024192B1 (pt) 2022-08-16

Similar Documents

Publication Publication Date Title
CA2945961C (en) (meth)acrylamide polymers for contact lens and intraocular lens
AU2016204924B2 (en) Hydrophobic intraocular lens
EP1077952B1 (en) Polymerizable hydrophilic ultraviolet light absorbing monomers
US6673886B2 (en) High refractive index hydrogel compositions for ophthalmic implants
EP3555677B1 (en) High refractive index hydrophilic materials
EP2822505A2 (en) Improved polymers and methods for ophthalmic applications
CN105793303A (zh) 软质疏水性丙烯酸材料
AU2017266896A1 (en) Hydrophobic intraocular lens
US20150038612A1 (en) Polymers and methods for ophthalmic applications
US12226545B2 (en) Micro injectable, low chromatic aberration intraocular lens materials
CA2964767A1 (en) Polymers and methods for opthalmic applications
HK1229267A1 (en) (meth)acrylamide polymers for contact lens and intraocular lens
HK1229267B (zh) 用於隐形眼镜和人工晶状体的(甲基)丙烯酰胺聚合物
JP2025532268A (ja) 複数のコモノマーグループを有する眼科用組成物及び眼科用レンズ
BR112019024078B1 (pt) Lente intraocular, composição e método para fabricar uma lente intraocular compreendendo pelo menos um copolímero compreendendo subunidades monoméricas
HK1199647B (en) Hydrophobic intraocular lens

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20200319

EEER Examination request

Effective date: 20200319

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 10TH ANNIV.) - STANDARD

Year of fee payment: 10

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250325

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20250325