JP6630388B2 - ラクトバチルスプランタルムtci378、およびそれを用いた脂肪の減少および胃腸機能の改善における使用 - Google Patents
ラクトバチルスプランタルムtci378、およびそれを用いた脂肪の減少および胃腸機能の改善における使用 Download PDFInfo
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- JP6630388B2 JP6630388B2 JP2018051654A JP2018051654A JP6630388B2 JP 6630388 B2 JP6630388 B2 JP 6630388B2 JP 2018051654 A JP2018051654 A JP 2018051654A JP 2018051654 A JP2018051654 A JP 2018051654A JP 6630388 B2 JP6630388 B2 JP 6630388B2
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- lactobacillus plantarum
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- tci378
- plantarum tci378
- food
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/25—Lactobacillus plantarum
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Description
(1)前脂肪細胞増殖培地:
・90%ダルベッコ改変イーグル培地(DMEM;Gibcoから購入)
・10%ウシ血清(Gibcoから購入)
・1%ペニシリン−ストレプトマイシン(Gibcoから購入)
(2)分化培地:
・90%ダルベッコ改変イーグル培地(DMEM;Gibcoから購入)
・10%ウシ胎仔血清(Gibcoから購入)
・1%ペニシリン−ストレプトマイシン(Gibcoから購入)
・1.0μmol/mLデキサメタゾン(Sigmaから購入)
・0.5mmol/mLメチルイソブチルキサンチン(Sigmaから購入)
・1.0μg/mLインスリン(Sigmaから購入)
(3)脂肪細胞維持培地:
・90%ダルベッコ改変イーグル培地(DMEM;Gibcoから購入)
・10%ウシ胎仔血清(Gibcoから購入)
・1%ペニシリン−ストレプトマイシン(Gibcoから購入)
・1.0μg/mLインスリン(Sigmaから購入)
(微生物の寄託)
寄託機関:ジャーマンコレクション・オブ・マイクロオーガニズム・アンド・セルカルチャー(Deutsche Sammlung von Mikroorganismen und Zellkulturen、DSMZ)
住所:インフォッフェンシュトラーセ7B、38124 ブラウンシュヴァイク、ドイツ
日付:2017年3月13日
寄託された微生物:ラクトバチルスプランタルムTCI378
受付番号:DSM32451
Claims (5)
- ラクトバチルスプランタルム(Lactobacillus plantarum)TCI378を含む組成物であって、
ここで、ラクトバチルスプランタルムTCI378は、ジャーマンコレクション・オブ・マイクロオーガニズム・アンド・セルカルチャー(Deutsche Sammlung von Mikroorganismen und Zellkulturen、DSMZ)に、寄託番号DSM32451として寄託されており、
前記組成物は、PLIN1遺伝子の発現レベルを減少させるためまたはGLUT4遺伝子の発現レベルを減少させるために用いられ、
ここで、前記組成物は、ラクトバチルスプランタルムTCI378の代謝産物を更に含んでいてもよく、
そしてここで、前記代謝産物は、培地中でラクトバチルスプランタルムTCI378を培養することにより得られる、前記組成物。 - 脂肪形成の低減、脂肪代謝の増強、体脂肪形成の阻止、および胃腸機能の改善のうちの少なくとも1つのための、請求項1に記載の組成物。
- 医薬組成物、食品組成物または飼料組成物である、請求項2に記載の組成物。
- 経口投与のための医薬組成物である、請求項3に記載の組成物。
- 食品組成物であって、前記食品組成物が健康食品、日常補助食品、機能性食品、栄養補助食品または特別栄養食品である、請求項3に記載の組成物。
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Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762473785P | 2017-03-20 | 2017-03-20 | |
US62/473,785 | 2017-03-20 |
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JP2018153182A JP2018153182A (ja) | 2018-10-04 |
JP6630388B2 true JP6630388B2 (ja) | 2020-01-15 |
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JP2018051654A Active JP6630388B2 (ja) | 2017-03-20 | 2018-03-19 | ラクトバチルスプランタルムtci378、およびそれを用いた脂肪の減少および胃腸機能の改善における使用 |
Country Status (5)
Country | Link |
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US (2) | US20180264054A1 (ja) |
JP (1) | JP6630388B2 (ja) |
KR (1) | KR102033031B1 (ja) |
CN (1) | CN108624523B (ja) |
TW (1) | TWI645854B (ja) |
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TWI725464B (zh) * | 2018-07-03 | 2021-04-21 | 大江生醫股份有限公司 | 減脂之益生菌株及其組合物與用途 |
CN111297912A (zh) * | 2018-12-12 | 2020-06-19 | 生合生物科技股份有限公司 | 胚芽乳酸杆菌twk10制备抗运动后发炎或降体脂组合物的用途 |
KR102606952B1 (ko) * | 2018-12-12 | 2023-11-29 | 신바이오 테크 인코포레이티드 | 운동 후 염증을 개선시키거나 체지방을 감소시키기 위한 락토바실러스 플란타룸 twk10 조성물의 방법 |
KR102177552B1 (ko) * | 2018-12-28 | 2020-11-11 | 건국대학교 산학협력단 | 락토바실러스 프란타룸 g72 균주를 포함하는 위장관 질환 예방 또는 치료용 조성물 |
TWI747280B (zh) * | 2019-05-17 | 2021-11-21 | 大江生醫股份有限公司 | 余甘子萃取發酵物及其製備與應用 |
TWI757911B (zh) * | 2019-10-07 | 2022-03-11 | 大江生醫股份有限公司 | 奇異果發酵汁液用於改善肌膚狀況的用途 |
CN110684701B (zh) * | 2019-11-19 | 2021-02-12 | 西南大学 | 植物乳杆菌s58及其在制备用于缓解肥胖的产品中的应用 |
KR102136335B1 (ko) * | 2020-03-24 | 2020-07-22 | (주)메디톡스 | 간기능 개선 또는 지방축적 억제 미생물 및 그의 용도 |
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- 2018-03-14 CN CN201810210650.7A patent/CN108624523B/zh active Active
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US11273189B2 (en) | 2022-03-15 |
CN108624523A (zh) | 2018-10-09 |
US20200254034A1 (en) | 2020-08-13 |
TWI645854B (zh) | 2019-01-01 |
US20180264054A1 (en) | 2018-09-20 |
KR20180106987A (ko) | 2018-10-01 |
KR102033031B1 (ko) | 2019-10-17 |
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CN108624523B (zh) | 2020-10-02 |
TW201834675A (zh) | 2018-10-01 |
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