JP6545959B2 - Ｒスポンジン転位およびその使用方法 - Google Patents

Ｒスポンジン転位およびその使用方法 Download PDF

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Publication number
JP6545959B2
JP6545959B2 JP2014556773A JP2014556773A JP6545959B2 JP 6545959 B2 JP6545959 B2 JP 6545959B2 JP 2014556773 A JP2014556773 A JP 2014556773A JP 2014556773 A JP2014556773 A JP 2014556773A JP 6545959 B2 JP6545959 B2 JP 6545959B2
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translocation
cancer
rearrangement
rspo3
rspo2
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Expired - Fee Related
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Japanese (ja)
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JP2015513529A (ja
JP2015513529A5 (https=
Inventor
ゾラ モドルーサン，
ゾラ モドルーサン，
ソヴァージュ， フレデリック ジェー． ドゥ
ソヴァージュ， フレデリック ジェー． ドゥ
ステファン ダリンク，
ステファン ダリンク，
ソマセカー セシャギリ，
ソマセカー セシャギリ，
エリック ウィリアム スタビスキ，
エリック ウィリアム スタビスキ，
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Genentech Inc
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014556773A 2012-02-11 2013-02-11 Ｒスポンジン転位およびその使用方法 Expired - Fee Related JP6545959B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261597746P 2012-02-11 2012-02-11
US61/597,746 2012-02-11
US201261674763P 2012-07-23 2012-07-23
US61/674,763 2012-07-23
PCT/US2013/025525 WO2013120056A1 (en) 2012-02-11 2013-02-11 R-spondin translocations and methods using the same

Related Child Applications (1)

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JP2017176424A Division JP2018021068A (ja) 2012-02-11 2017-09-14 Ｒスポンジン転位およびその使用方法

Publications (3)

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JP2015513529A JP2015513529A (ja) 2015-05-14
JP2015513529A5 JP2015513529A5 (https=) 2016-03-31
JP6545959B2 true JP6545959B2 (ja) 2019-07-17

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JP2014556773A Expired - Fee Related JP6545959B2 (ja) 2012-02-11 2013-02-11 Ｒスポンジン転位およびその使用方法
JP2017176424A Pending JP2018021068A (ja) 2012-02-11 2017-09-14 Ｒスポンジン転位およびその使用方法

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US (2) US20130209473A1 (https=)
EP (1) EP2812350B1 (https=)
JP (2) JP6545959B2 (https=)
KR (1) KR102148303B1 (https=)
CN (2) CN113398268A (https=)
AR (1) AR089978A1 (https=)
AU (1) AU2013216753B2 (https=)
BR (1) BR112014019741A2 (https=)
CA (1) CA2862316A1 (https=)
HK (1) HK1211037A1 (https=)
IL (2) IL233680B (https=)
MX (1) MX366804B (https=)
RU (1) RU2014133069A (https=)
SG (1) SG11201404703WA (https=)
WO (1) WO2013120056A1 (https=)
ZA (1) ZA201406620B (https=)

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US9777052B2 (en) 2014-12-02 2017-10-03 The Board Of Regents Of The University Of Oklahoma R-spondin variants, compositions, and methods of use
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US11104953B2 (en) 2016-05-13 2021-08-31 Children's Hospital Medical Center Septic shock endotyping strategy and mortality risk for clinical application
EP3455621B1 (en) * 2016-05-13 2023-07-19 Cincinnati Children's Hospital Medical Center Simplification of a septic shock endotyping strategy for clinical application
HRP20260151T1 (hr) * 2016-08-02 2026-03-27 Visterra, Inc. Modificirani polipeptidi i njihova uporaba
US10815534B2 (en) * 2016-08-23 2020-10-27 Mayo Foundation For Medical Education And Research Methods and materials for treating estrogen receptor positive breast cancer
WO2018075947A1 (en) * 2016-10-20 2018-04-26 The Regents Of The University Of California Methods and compositions for the treatment of rna viral infections
JP7419068B2 (ja) * 2016-12-21 2024-01-22 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 悪性腫瘍を特定するためのキット及びその使用
US12275994B2 (en) 2017-06-22 2025-04-15 Clear Gene, Inc. Methods and compositions for the analysis of cancer biomarkers
WO2021070739A1 (ja) * 2019-10-08 2021-04-15 国立大学法人 東京大学 分析装置、分析方法及びプログラム
CN114830674B (zh) 2019-12-27 2024-07-19 日本放送协会 发送装置和接收装置
CN114480632B (zh) * 2020-11-16 2023-05-16 江萤 人微卫星不稳定位点的检测方法及其应用
CN113957075B (zh) * 2021-11-22 2023-04-07 百世诺(北京)医学检验实验室有限公司 突变的遗传性心律失常基因及其应用
CN114107482A (zh) * 2021-11-29 2022-03-01 百世诺(北京)医学检验实验室有限公司 肺动脉高压突变基因及其应用
KR102554222B1 (ko) * 2023-03-21 2023-07-11 순천향대학교 산학협력단 신규한 항-인간 알스폰딘3 항체 및 이의 용도
KR102551095B1 (ko) * 2023-03-21 2023-07-04 순천향대학교 산학협력단 신규한 항-인간 알스폰딘2 항체 및 이의 용도
CN119656337A (zh) * 2024-11-06 2025-03-21 中山大学附属第六医院 肿瘤细胞pcbp1基因突变调控cd8+t细胞在制备免疫治疗药物或制剂中的用途

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