JP6420331B2 - タンパク質−高分子−薬剤コンジュゲート - Google Patents

タンパク質−高分子−薬剤コンジュゲート Download PDF

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JP6420331B2
JP6420331B2 JP2016522030A JP2016522030A JP6420331B2 JP 6420331 B2 JP6420331 B2 JP 6420331B2 JP 2016522030 A JP2016522030 A JP 2016522030A JP 2016522030 A JP2016522030 A JP 2016522030A JP 6420331 B2 JP6420331 B2 JP 6420331B2
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integer
kda
polymer
cancer
phf
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JP2016535728A (ja
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ブイ．ユルコフェツキー アレクサンドル
ブイ．ユルコフェツキー アレクサンドル
イン マオ
イン マオ
ビー．ローインガー ティモシー
ビー．ローインガー ティモシー
ディー．トーマス ジョシュア
ディー．トーマス ジョシュア
エー．スティーブンソン シェリ
エー．スティーブンソン シェリ
アール．グリジャラ ベニュー
アール．グリジャラ ベニュー
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メルサナ セラピューティクス，インコーポレイティド
メルサナ セラピューティクス，インコーポレイティド
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    • A—HUMAN NECESSITIES
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
JP2016522030A 2013-10-11 2014-10-10 タンパク質−高分子−薬剤コンジュゲート Active JP6420331B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201361890046P 2013-10-11 2013-10-11
US61/890,046 2013-10-11
US201461975455P 2014-04-04 2014-04-04
US61/975,455 2014-04-04
US201461988011P 2014-05-02 2014-05-02
US61/988,011 2014-05-02
US201462010972P 2014-06-11 2014-06-11
US62/010,972 2014-06-11
PCT/US2014/060170 WO2015054659A1 (en) 2013-10-11 2014-10-10 Protein-polymer-drug conjugates

Publications (2)

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JP2016535728A JP2016535728A (ja) 2016-11-17
JP6420331B2 true JP6420331B2 (ja) 2018-11-07

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US (2) US9849191B2 (https=)
EP (1) EP3054991B1 (https=)
JP (1) JP6420331B2 (https=)
KR (1) KR102087850B1 (https=)
CN (1) CN105979970B (https=)
AU (1) AU2014331714B2 (https=)
BR (1) BR112016007736B1 (https=)
CA (1) CA2926586C (https=)
DK (1) DK3054991T3 (https=)
EA (1) EA032231B1 (https=)
ES (1) ES2726850T3 (https=)
IL (1) IL244816B (https=)
MX (1) MX367851B (https=)
WO (1) WO2015054659A1 (https=)

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JP6971858B2 (ja) 2015-06-22 2021-11-24 バイエル ファーマ アクチエンゲゼルシャフト 酵素開裂性基を有する抗体薬物複合体（ａｄｃ）および抗体プロドラッグ複合体（ａｐｄｃ）
JP2018524313A (ja) * 2015-06-23 2018-08-30 バイエル ファーマ アクチエンゲゼルシャフト キネシンスピンドルタンパク質（ｋｓｐ）阻害剤の抗ｂ７ｈ３抗体との抗体薬物複合体
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