JP6345603B2 - 追加免疫ワクチンのアジュバント化された処方物 - Google Patents

追加免疫ワクチンのアジュバント化された処方物 Download PDF

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JP6345603B2
JP6345603B2 JP2014560382A JP2014560382A JP6345603B2 JP 6345603 B2 JP6345603 B2 JP 6345603B2 JP 2014560382 A JP2014560382 A JP 2014560382A JP 2014560382 A JP2014560382 A JP 2014560382A JP 6345603 B2 JP6345603 B2 JP 6345603B2
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composition
toxoid
alkyl
composition according
pertussis
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JP2015509522A5 (https=
JP2015509522A (ja
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シモーネ ブファーリ，
シモーネ ブファーリ，
ババラ バウドナー，
ババラ バウドナー，
デレク オーヘイガン，
デレク オーヘイガン，
シン，　マンモハン
マンモハン シン，
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ノバルティス アーゲー
ノバルティス アーゲー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/13—Poliovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014560382A 2012-03-08 2013-03-08 追加免疫ワクチンのアジュバント化された処方物 Active JP6345603B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261608398P 2012-03-08 2012-03-08
US61/608,398 2012-03-08
US201261697730P 2012-09-06 2012-09-06
US61/697,730 2012-09-06
PCT/EP2013/054672 WO2013132041A2 (en) 2012-03-08 2013-03-08 Adjuvanted formulations of booster vaccines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017096343A Division JP2017132821A (ja) 2012-03-08 2017-05-15 追加免疫ワクチンのアジュバント化された処方物

Publications (3)

Publication Number Publication Date
JP2015509522A JP2015509522A (ja) 2015-03-30
JP2015509522A5 JP2015509522A5 (https=) 2016-04-21
JP6345603B2 true JP6345603B2 (ja) 2018-06-20

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JP2014560382A Active JP6345603B2 (ja) 2012-03-08 2013-03-08 追加免疫ワクチンのアジュバント化された処方物
JP2017096343A Withdrawn JP2017132821A (ja) 2012-03-08 2017-05-15 追加免疫ワクチンのアジュバント化された処方物
JP2018194314A Pending JP2019001832A (ja) 2012-03-08 2018-10-15 追加免疫ワクチンのアジュバント化された処方物
JP2021015094A Active JP7295895B2 (ja) 2012-03-08 2021-02-02 追加免疫ワクチンのアジュバント化された処方物
JP2023045185A Pending JP2023085364A (ja) 2012-03-08 2023-03-22 追加免疫ワクチンのアジュバント化された処方物

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JP2017096343A Withdrawn JP2017132821A (ja) 2012-03-08 2017-05-15 追加免疫ワクチンのアジュバント化された処方物
JP2018194314A Pending JP2019001832A (ja) 2012-03-08 2018-10-15 追加免疫ワクチンのアジュバント化された処方物
JP2021015094A Active JP7295895B2 (ja) 2012-03-08 2021-02-02 追加免疫ワクチンのアジュバント化された処方物
JP2023045185A Pending JP2023085364A (ja) 2012-03-08 2023-03-22 追加免疫ワクチンのアジュバント化された処方物

Country Status (9)

Country Link
US (3) US9375471B2 (https=)
EP (1) EP2822581A2 (https=)
JP (5) JP6345603B2 (https=)
CN (1) CN104159602B (https=)
AU (1) AU2013229432A1 (https=)
CA (1) CA2866406A1 (https=)
MX (1) MX372965B (https=)
RU (1) RU2014140521A (https=)
WO (1) WO2013132041A2 (https=)

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JP2017132821A (ja) 2017-08-03
AU2013229432A1 (en) 2014-10-16
CA2866406A1 (en) 2013-09-12
WO2013132041A2 (en) 2013-09-12
JP2023085364A (ja) 2023-06-20
US9375471B2 (en) 2016-06-28
US10842868B2 (en) 2020-11-24
US20160263216A1 (en) 2016-09-15
JP2019001832A (ja) 2019-01-10
JP2021088564A (ja) 2021-06-10
JP2015509522A (ja) 2015-03-30
JP7295895B2 (ja) 2023-06-21
MX2014010417A (es) 2014-09-22
EP2822581A2 (en) 2015-01-14
US20180177871A1 (en) 2018-06-28
US20130236492A1 (en) 2013-09-12
MX372965B (es) 2020-04-01
CN104159602B (zh) 2017-10-24

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