JP6313479B2 - 有機セレン化合物の組成物およびその使用方法 - Google Patents

有機セレン化合物の組成物およびその使用方法 Download PDF

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JP6313479B2
JP6313479B2 JP2016575297A JP2016575297A JP6313479B2 JP 6313479 B2 JP6313479 B2 JP 6313479B2 JP 2016575297 A JP2016575297 A JP 2016575297A JP 2016575297 A JP2016575297 A JP 2016575297A JP 6313479 B2 JP6313479 B2 JP 6313479B2
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alkyl
cells
compounds
formula
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JP2017512828A (ja
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パワー，ローナン
ラン，ジージェン
イアニクーリス，アレキサンドロス
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オールテック，インク．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Inorganic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
JP2016575297A 2014-03-14 2014-03-14 有機セレン化合物の組成物およびその使用方法 Active JP6313479B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2014/029542 WO2015137983A1 (en) 2014-03-14 2014-03-14 Compositions of selenoorganic compounds and methods of use thereof

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JP2017512828A JP2017512828A (ja) 2017-05-25
JP6313479B2 true JP6313479B2 (ja) 2018-04-18

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JP2016178302A Active JP7009053B2 (ja) 2014-03-14 2016-09-13 有機セレン化合物の組成物およびその使用方法

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EP (1) EP3116511B1 (enExample)
JP (2) JP6313479B2 (enExample)
KR (3) KR102448455B1 (enExample)
CN (3) CN113694074A (enExample)
AU (4) AU2014386236B2 (enExample)
BR (1) BR112016020233B1 (enExample)
CA (1) CA2940283C (enExample)
DK (2) DK3116511T3 (enExample)
HU (2) HUE051713T2 (enExample)
IL (1) IL247312A0 (enExample)
MX (2) MX2016011897A (enExample)
PE (1) PE20211069A1 (enExample)
PT (1) PT3116511T (enExample)
RU (2) RU2665135C2 (enExample)
WO (2) WO2015137983A1 (enExample)

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RU2016136530A3 (enExample) 2019-11-25
RU2016133469A (ru) 2018-04-17
KR20210104070A (ko) 2021-08-24
BR112016020233B1 (pt) 2022-07-19
HUE056172T2 (hu) 2022-01-28
CA2940283C (en) 2021-03-30
KR102764247B1 (ko) 2025-02-07
HUE051713T2 (hu) 2021-03-29
RU2731383C2 (ru) 2020-09-02
EP3116511A1 (en) 2017-01-18
CN106822168A (zh) 2017-06-13
US20160082033A1 (en) 2016-03-24
JP7009053B2 (ja) 2022-01-25
PE20211069A1 (es) 2021-06-09
MX2016011897A (es) 2017-04-27
KR102448455B1 (ko) 2022-09-28
EP3116511B1 (en) 2020-08-26
US10201558B2 (en) 2019-02-12
JP2017078056A (ja) 2017-04-27
PT3116511T (pt) 2020-11-19
WO2017048253A1 (en) 2017-03-23
US10201559B2 (en) 2019-02-12
AU2019246818B2 (en) 2021-02-25
RU2016136530A (ru) 2018-03-16
AU2019246818A1 (en) 2019-10-31
AU2016222315A1 (en) 2017-03-30
KR20160125989A (ko) 2016-11-01
NZ723233A (en) 2020-10-30
CA2940283A1 (en) 2015-09-17
AU2016222315B2 (en) 2022-08-04
CN106822168B (zh) 2020-11-27
JP2017512828A (ja) 2017-05-25
MX2016011898A (es) 2018-03-12
DK3116511T3 (da) 2020-11-23
CN106456658A (zh) 2017-02-22
WO2015137983A1 (en) 2015-09-17
CN113694074A (zh) 2021-11-26
AU2014386236A1 (en) 2016-09-01
BR112016020233A2 (enExample) 2017-08-15
AU2022204588A1 (en) 2022-07-21
US20160361338A1 (en) 2016-12-15
IL247312A0 (en) 2016-09-29
NZ723402A (en) 2024-11-29
AU2014386236B2 (en) 2019-07-11
EP3116511A4 (en) 2017-10-18
KR20170032862A (ko) 2017-03-23
BR102016021058A2 (pt) 2017-05-30
RU2665135C2 (ru) 2018-08-28
US9642874B2 (en) 2017-05-09
US20160045533A1 (en) 2016-02-18
DK3144001T3 (da) 2021-11-15
KR102466389B1 (ko) 2022-11-11

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