JP6305920B2 - 併用療法 - Google Patents
併用療法 Download PDFInfo
- Publication number
- JP6305920B2 JP6305920B2 JP2014517338A JP2014517338A JP6305920B2 JP 6305920 B2 JP6305920 B2 JP 6305920B2 JP 2014517338 A JP2014517338 A JP 2014517338A JP 2014517338 A JP2014517338 A JP 2014517338A JP 6305920 B2 JP6305920 B2 JP 6305920B2
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- receptor
- individual
- cell
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011902623 | 2011-07-01 | ||
| AU2011902623A AU2011902623A0 (en) | 2011-07-01 | Combination therapy | |
| PCT/AU2012/000795 WO2013003895A1 (en) | 2011-07-01 | 2012-07-02 | Combination therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018039564A Division JP6490270B2 (ja) | 2011-07-01 | 2018-03-06 | 併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520759A JP2014520759A (ja) | 2014-08-25 |
| JP2014520759A5 JP2014520759A5 (https=) | 2015-08-20 |
| JP6305920B2 true JP6305920B2 (ja) | 2018-04-04 |
Family
ID=47436374
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014517338A Active JP6305920B2 (ja) | 2011-07-01 | 2012-07-02 | 併用療法 |
| JP2018039564A Active JP6490270B2 (ja) | 2011-07-01 | 2018-03-06 | 併用療法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018039564A Active JP6490270B2 (ja) | 2011-07-01 | 2018-03-06 | 併用療法 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9566318B2 (https=) |
| EP (1) | EP2726095B1 (https=) |
| JP (2) | JP6305920B2 (https=) |
| CN (1) | CN103702683B (https=) |
| AU (1) | AU2012278921B2 (https=) |
| BR (1) | BR112013033974A2 (https=) |
| CA (1) | CA2840251C (https=) |
| ES (1) | ES2689272T3 (https=) |
| MX (1) | MX349321B (https=) |
| WO (1) | WO2013003895A1 (https=) |
| ZA (1) | ZA201400120B (https=) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10010075B2 (en) | 2010-12-29 | 2018-07-03 | Ecolab Usa Inc. | Water temperature as a means of controlling kinetics of onsite generated peracids |
| US10233149B2 (en) | 2014-12-18 | 2019-03-19 | Ecolab Usa Inc. | Methods for forming peroxyformic acid and uses thereof |
| US10433547B2 (en) | 2014-12-18 | 2019-10-08 | Ecolab Usa Inc. | Generation of peroxyformic acid through polyhydric alcohol formate |
| US10477862B2 (en) | 2010-12-29 | 2019-11-19 | Ecolab Usa Inc. | In situ generation of peroxycarboxylic acids at alkaline pH, and methods of use thereof |
| US11040902B2 (en) | 2014-12-18 | 2021-06-22 | Ecolab Usa Inc. | Use of percarboxylic acids for scale prevention in treatment systems |
| US11180385B2 (en) | 2012-10-05 | 2021-11-23 | Ecolab USA, Inc. | Stable percarboxylic acid compositions and uses thereof |
| US12058999B2 (en) | 2018-08-22 | 2024-08-13 | Ecolab Usa Inc. | Hydrogen peroxide and peracid stabilization with molecules based on a pyridine carboxylic acid |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4384852B2 (ja) | 2001-01-17 | 2009-12-16 | イントリート ピーティーワイ リミテッド | 非機能性p2x7レセプター抗体、癌及びその他の容態の診断及び処置 |
| ES2619681T3 (es) | 2007-09-14 | 2017-06-26 | Biosceptre (Aust) Pty Ltd | Novedosos epítopos P2X7 |
| CN102143978B (zh) | 2008-07-04 | 2015-02-18 | 生物权威国际有限公司 | 抗p2x7肽和表位 |
| EP2467404B1 (en) | 2009-08-20 | 2015-09-30 | Biosceptre International Limited | Anti p2x7 receptor antibodies and fragments thereof |
| WO2011075789A1 (en) | 2009-12-24 | 2011-06-30 | Biosceptre International Limited | Antibodies to non-functional oligomeric p2x7 receptors |
| EP2613808B1 (en) | 2010-09-10 | 2017-11-08 | Biosceptre (Aust) Pty Ltd | Companion animal cancer treatments with an anti p2x7 antibody |
| MX349321B (es) | 2011-07-01 | 2017-07-21 | Biosceptre (Aust) Pty Ltd | Terapia combinada. |
| US12121539B2 (en) | 2015-09-11 | 2024-10-22 | Biosceptre (Aust) Pty Ltd | Chimeric antigen receptors and uses thereof |
| MX2019004410A (es) * | 2016-10-21 | 2019-09-26 | Biosceptre Uk Ltd | Particulas citotoxicas. |
| WO2020227159A2 (en) | 2019-05-03 | 2020-11-12 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity |
| CN114173811A (zh) * | 2019-07-26 | 2022-03-11 | 生物权威(澳大利亚)有限责任公司 | P2x7受体靶向治疗 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE920765A1 (en) | 1991-03-12 | 1992-09-23 | Scripps Research Inst | Cell surface receptors homologous to coagulation factors v¹and viii |
| US5500161A (en) | 1993-09-21 | 1996-03-19 | Massachusetts Institute Of Technology And Virus Research Institute | Method for making hydrophobic polymeric microparticles |
| AU2566595A (en) | 1994-05-27 | 1995-12-21 | Glaxo Group Limited | P-2x receptors (purinoceptor family) |
| WO1997006256A2 (en) | 1995-08-09 | 1997-02-20 | Institut National De La Sante Et De La Recherche Medicale | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis |
| JP2001521372A (ja) | 1996-04-30 | 2001-11-06 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ヒトP2x4レセプタースプライス−変異体 |
| US6303338B1 (en) | 1996-08-16 | 2001-10-16 | Human Genome Sciences, Inc. | Pancreas-derived plasminogen activator inhibitor |
| US6306393B1 (en) | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| JP3885177B2 (ja) | 1997-03-26 | 2007-02-21 | 大塚製薬株式会社 | ヒト遺伝子 |
| US6133434A (en) | 1997-04-28 | 2000-10-17 | Glaxo Group Limited | Purinergic receptor |
| EP1086223B1 (en) | 1998-06-01 | 2009-07-29 | Agensys, Inc. | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof |
| DE19829473C2 (de) | 1998-07-01 | 2000-08-10 | Magnus Von Knebel Doeberitz Ch | Verfahren zur frühen Diagnose von Carcinomen |
| EP1157038A4 (en) | 1999-02-26 | 2005-01-19 | Smithkline Beecham Corp | CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17) |
| AUPP991199A0 (en) | 1999-04-21 | 1999-05-13 | University Of Sydney, The | Methods for diagnosing pre-cancerous and cancerous conditions |
| NL1012452C2 (nl) | 1999-06-28 | 2001-01-02 | Univ Delft Tech | Werkwijze voor de bereiding van eiwit-agglomeraten, eiwit-agglomeraten, een levensmiddel en een farmaceutisch preparaat die deze bevatten alsmede een inrichting voor het bereiden van eiwit-agglomeraten. |
| AU1339701A (en) | 1999-10-22 | 2001-05-08 | Lifespan Biosciences, Inc. | Anti-cancer nucleic acid and protein targets |
| AUPR201500A0 (en) | 2000-12-11 | 2001-01-11 | Biosceptre Pty Ltd | Methods for identifying pre-neoplastic and neoplastic states in mammals |
| JP4384852B2 (ja) | 2001-01-17 | 2009-12-16 | イントリート ピーティーワイ リミテッド | 非機能性p2x7レセプター抗体、癌及びその他の容態の診断及び処置 |
| CN100497386C (zh) | 2001-09-03 | 2009-06-10 | 因特里特有限公司 | 非功能性p2x7受体的抗体及其应用 |
| EP1469072B1 (en) | 2003-04-17 | 2007-08-29 | Affectis Pharmaceuticals AG | Means and methods for diagnosing and treating affective disorders |
| DE602005017743D1 (de) * | 2004-01-23 | 2009-12-31 | Angeletti P Ist Richerche Bio | Impfstoffträger für schimpansen-adenovirus |
| US7858323B2 (en) * | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
| GB0419295D0 (en) * | 2004-08-31 | 2004-09-29 | Genomica Sau | Methods and compositions to prevent neuronal degeneration |
| CA2607541A1 (en) | 2005-05-05 | 2006-12-28 | Medicure International Inc. | Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphaste and vitamin b6 related compounds |
| US7767789B2 (en) | 2005-06-02 | 2010-08-03 | University Hopitals of Cleveland | Truncated proteins as cancer markers |
| EP1929305A2 (en) | 2005-08-31 | 2008-06-11 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
| WO2008043146A1 (en) | 2006-10-10 | 2008-04-17 | Biosceptre International Limited | Antibodies against non functional p2x7 receptor |
| JP2010505426A (ja) | 2006-10-10 | 2010-02-25 | バイオスセプター インターナショナル リミテッド | 非機能性p2x7受容体に対する抗体を産生するハイブリドーマ |
| ATE542139T1 (de) | 2007-09-14 | 2012-02-15 | Biosceptre Int Ltd | Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit |
| ES2619681T3 (es) * | 2007-09-14 | 2017-06-26 | Biosceptre (Aust) Pty Ltd | Novedosos epítopos P2X7 |
| CN102143978B (zh) | 2008-07-04 | 2015-02-18 | 生物权威国际有限公司 | 抗p2x7肽和表位 |
| KR20170097234A (ko) * | 2008-12-10 | 2017-08-25 | 더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드 | 유방암 재발 예방용 백신 |
| EP2467404B1 (en) | 2009-08-20 | 2015-09-30 | Biosceptre International Limited | Anti p2x7 receptor antibodies and fragments thereof |
| WO2011075789A1 (en) * | 2009-12-24 | 2011-06-30 | Biosceptre International Limited | Antibodies to non-functional oligomeric p2x7 receptors |
| US8828944B2 (en) * | 2010-04-22 | 2014-09-09 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
| EP2613808B1 (en) | 2010-09-10 | 2017-11-08 | Biosceptre (Aust) Pty Ltd | Companion animal cancer treatments with an anti p2x7 antibody |
| MX349321B (es) | 2011-07-01 | 2017-07-21 | Biosceptre (Aust) Pty Ltd | Terapia combinada. |
-
2012
- 2012-07-02 MX MX2014000199A patent/MX349321B/es active IP Right Grant
- 2012-07-02 EP EP12807960.5A patent/EP2726095B1/en active Active
- 2012-07-02 CN CN201280033124.9A patent/CN103702683B/zh active Active
- 2012-07-02 BR BR112013033974A patent/BR112013033974A2/pt not_active Application Discontinuation
- 2012-07-02 AU AU2012278921A patent/AU2012278921B2/en active Active
- 2012-07-02 CA CA2840251A patent/CA2840251C/en active Active
- 2012-07-02 ES ES12807960.5T patent/ES2689272T3/es active Active
- 2012-07-02 US US14/129,240 patent/US9566318B2/en active Active
- 2012-07-02 WO PCT/AU2012/000795 patent/WO2013003895A1/en not_active Ceased
- 2012-07-02 JP JP2014517338A patent/JP6305920B2/ja active Active
-
2014
- 2014-01-07 ZA ZA2014/00120A patent/ZA201400120B/en unknown
-
2017
- 2017-01-05 US US15/399,337 patent/US10245308B2/en active Active
-
2018
- 2018-03-06 JP JP2018039564A patent/JP6490270B2/ja active Active
-
2019
- 2019-02-05 US US16/268,344 patent/US10543262B2/en active Active
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10010075B2 (en) | 2010-12-29 | 2018-07-03 | Ecolab Usa Inc. | Water temperature as a means of controlling kinetics of onsite generated peracids |
| US10201156B2 (en) | 2010-12-29 | 2019-02-12 | Ecolab Usa Inc. | Continuous on-line adjustable disinfectant/sanitizer/bleach generator |
| US11311011B2 (en) | 2010-12-29 | 2022-04-26 | Ecolab Usa Inc. | Continuous on-line adjustable disinfectant/sanitizer/bleach generator |
| US10244751B2 (en) | 2010-12-29 | 2019-04-02 | Ecolab Usa Inc. | Water temperature as a means of controlling kinetics of onsite generated peracids |
| US10477862B2 (en) | 2010-12-29 | 2019-11-19 | Ecolab Usa Inc. | In situ generation of peroxycarboxylic acids at alkaline pH, and methods of use thereof |
| US11180385B2 (en) | 2012-10-05 | 2021-11-23 | Ecolab USA, Inc. | Stable percarboxylic acid compositions and uses thereof |
| US10542751B2 (en) | 2014-12-18 | 2020-01-28 | Ecolab Usa Inc. | Generation of peroxyformic acid through polyhydric alcohol formate |
| US10709131B2 (en) | 2014-12-18 | 2020-07-14 | Ecolab Usa Inc. | Generation of peroxyformic acid through polyhydric alcohol formate |
| US10834924B2 (en) | 2014-12-18 | 2020-11-17 | Ecolab Usa Inc. | Generation of peroxyformic acid through polyhydric alcohol formate |
| US10899707B2 (en) | 2014-12-18 | 2021-01-26 | Ecolab Usa Inc. | Methods for forming peroxyformic acid and uses thereof |
| US11040902B2 (en) | 2014-12-18 | 2021-06-22 | Ecolab Usa Inc. | Use of percarboxylic acids for scale prevention in treatment systems |
| US10433547B2 (en) | 2014-12-18 | 2019-10-08 | Ecolab Usa Inc. | Generation of peroxyformic acid through polyhydric alcohol formate |
| US10233149B2 (en) | 2014-12-18 | 2019-03-19 | Ecolab Usa Inc. | Methods for forming peroxyformic acid and uses thereof |
| US11684067B2 (en) | 2014-12-18 | 2023-06-27 | Ecolab Usa Inc. | Generation of peroxyformic acid through polyhydric alcohol formate |
| US12058999B2 (en) | 2018-08-22 | 2024-08-13 | Ecolab Usa Inc. | Hydrogen peroxide and peracid stabilization with molecules based on a pyridine carboxylic acid |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2689272T3 (es) | 2018-11-13 |
| BR112013033974A2 (pt) | 2017-02-14 |
| AU2012278921A1 (en) | 2014-01-16 |
| ZA201400120B (en) | 2015-09-30 |
| EP2726095A4 (en) | 2015-01-07 |
| CA2840251A1 (en) | 2013-01-10 |
| JP2018087249A (ja) | 2018-06-07 |
| US10543262B2 (en) | 2020-01-28 |
| US20190224290A1 (en) | 2019-07-25 |
| CN103702683A (zh) | 2014-04-02 |
| US20150004179A1 (en) | 2015-01-01 |
| US20170157229A1 (en) | 2017-06-08 |
| AU2012278921B2 (en) | 2016-11-10 |
| JP2014520759A (ja) | 2014-08-25 |
| CA2840251C (en) | 2023-09-12 |
| MX349321B (es) | 2017-07-21 |
| EP2726095B1 (en) | 2018-06-06 |
| MX2014000199A (es) | 2014-06-11 |
| CN103702683B (zh) | 2017-07-04 |
| US10245308B2 (en) | 2019-04-02 |
| JP6490270B2 (ja) | 2019-03-27 |
| EP2726095A1 (en) | 2014-05-07 |
| WO2013003895A1 (en) | 2013-01-10 |
| US9566318B2 (en) | 2017-02-14 |
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