CN103702683B - 联合治疗 - Google Patents

联合治疗 Download PDF

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Publication number
CN103702683B
CN103702683B CN201280033124.9A CN201280033124A CN103702683B CN 103702683 B CN103702683 B CN 103702683B CN 201280033124 A CN201280033124 A CN 201280033124A CN 103702683 B CN103702683 B CN 103702683B
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CN
China
Prior art keywords
cancer
receptor
individual
antibody
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201280033124.9A
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English (en)
Chinese (zh)
Other versions
CN103702683A (zh
Inventor
朱利安·亚历山大·巴登
安格斯·基得利-拜尔德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Authority (australia) LLC
Original Assignee
Bio Authority (australia) LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2011902623A external-priority patent/AU2011902623A0/en
Application filed by Bio Authority (australia) LLC filed Critical Bio Authority (australia) LLC
Publication of CN103702683A publication Critical patent/CN103702683A/zh
Application granted granted Critical
Publication of CN103702683B publication Critical patent/CN103702683B/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201280033124.9A 2011-07-01 2012-07-02 联合治疗 Active CN103702683B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2011902623 2011-07-01
AU2011902623A AU2011902623A0 (en) 2011-07-01 Combination therapy
PCT/AU2012/000795 WO2013003895A1 (en) 2011-07-01 2012-07-02 Combination therapy

Publications (2)

Publication Number Publication Date
CN103702683A CN103702683A (zh) 2014-04-02
CN103702683B true CN103702683B (zh) 2017-07-04

Family

ID=47436374

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280033124.9A Active CN103702683B (zh) 2011-07-01 2012-07-02 联合治疗

Country Status (11)

Country Link
US (3) US9566318B2 (https=)
EP (1) EP2726095B1 (https=)
JP (2) JP6305920B2 (https=)
CN (1) CN103702683B (https=)
AU (1) AU2012278921B2 (https=)
BR (1) BR112013033974A2 (https=)
CA (1) CA2840251C (https=)
ES (1) ES2689272T3 (https=)
MX (1) MX349321B (https=)
WO (1) WO2013003895A1 (https=)
ZA (1) ZA201400120B (https=)

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EP2467404B1 (en) 2009-08-20 2015-09-30 Biosceptre International Limited Anti p2x7 receptor antibodies and fragments thereof
WO2011075789A1 (en) 2009-12-24 2011-06-30 Biosceptre International Limited Antibodies to non-functional oligomeric p2x7 receptors
EP2613808B1 (en) 2010-09-10 2017-11-08 Biosceptre (Aust) Pty Ltd Companion animal cancer treatments with an anti p2x7 antibody
US8933263B2 (en) 2010-12-29 2015-01-13 Ecolab Usa Inc. Water temperature as a means of controlling kinetics of onsite generated peracids
US8846107B2 (en) 2010-12-29 2014-09-30 Ecolab Usa Inc. In situ generation of peroxycarboxylic acids at alkaline pH, and methods of use thereof
MX349321B (es) 2011-07-01 2017-07-21 Biosceptre (Aust) Pty Ltd Terapia combinada.
US9321664B2 (en) 2011-12-20 2016-04-26 Ecolab Usa Inc. Stable percarboxylic acid compositions and uses thereof
EP3766523A1 (en) 2014-12-18 2021-01-20 Ecolab USA Inc. Generation of peroxyformic acid through polyhydric alcohol formate
EP3232781A4 (en) 2014-12-18 2018-08-22 Ecolab USA Inc. Methods for forming peroxyformic acid and uses thereof
US11040902B2 (en) 2014-12-18 2021-06-22 Ecolab Usa Inc. Use of percarboxylic acids for scale prevention in treatment systems
US12121539B2 (en) 2015-09-11 2024-10-22 Biosceptre (Aust) Pty Ltd Chimeric antigen receptors and uses thereof
MX2019004410A (es) * 2016-10-21 2019-09-26 Biosceptre Uk Ltd Particulas citotoxicas.
EP3841059A1 (en) 2018-08-22 2021-06-30 Ecolab USA Inc. Hydrogen peroxide and peracid stabilization with molecules based on a pyridine carboxylic acid at c-3, -4 or -5
WO2020227159A2 (en) 2019-05-03 2020-11-12 Flagship Pioneering Innovations V, Inc. Methods of modulating immune activity
CN114173811A (zh) * 2019-07-26 2022-03-11 生物权威(澳大利亚)有限责任公司 P2x7受体靶向治疗

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EP1157038A4 (en) 1999-02-26 2005-01-19 Smithkline Beecham Corp CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17)
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CN102143978B (zh) 2008-07-04 2015-02-18 生物权威国际有限公司 抗p2x7肽和表位
KR20170097234A (ko) * 2008-12-10 2017-08-25 더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드 유방암 재발 예방용 백신
EP2467404B1 (en) 2009-08-20 2015-09-30 Biosceptre International Limited Anti p2x7 receptor antibodies and fragments thereof
WO2011075789A1 (en) * 2009-12-24 2011-06-30 Biosceptre International Limited Antibodies to non-functional oligomeric p2x7 receptors
US8828944B2 (en) * 2010-04-22 2014-09-09 Institut Gustave Roussy Compounds and uses thereof to induce an immunogenic cancer cell death in a subject
EP2613808B1 (en) 2010-09-10 2017-11-08 Biosceptre (Aust) Pty Ltd Companion animal cancer treatments with an anti p2x7 antibody
MX349321B (es) 2011-07-01 2017-07-21 Biosceptre (Aust) Pty Ltd Terapia combinada.

Patent Citations (1)

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Also Published As

Publication number Publication date
ES2689272T3 (es) 2018-11-13
BR112013033974A2 (pt) 2017-02-14
AU2012278921A1 (en) 2014-01-16
ZA201400120B (en) 2015-09-30
EP2726095A4 (en) 2015-01-07
CA2840251A1 (en) 2013-01-10
JP2018087249A (ja) 2018-06-07
US10543262B2 (en) 2020-01-28
US20190224290A1 (en) 2019-07-25
CN103702683A (zh) 2014-04-02
US20150004179A1 (en) 2015-01-01
US20170157229A1 (en) 2017-06-08
AU2012278921B2 (en) 2016-11-10
JP2014520759A (ja) 2014-08-25
CA2840251C (en) 2023-09-12
MX349321B (es) 2017-07-21
EP2726095B1 (en) 2018-06-06
MX2014000199A (es) 2014-06-11
US10245308B2 (en) 2019-04-02
JP6490270B2 (ja) 2019-03-27
EP2726095A1 (en) 2014-05-07
JP6305920B2 (ja) 2018-04-04
WO2013003895A1 (en) 2013-01-10
US9566318B2 (en) 2017-02-14

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