JP6293071B2 - 脈管穿刺を閉塞するための器具 - Google Patents
脈管穿刺を閉塞するための器具 Download PDFInfo
- Publication number
- JP6293071B2 JP6293071B2 JP2015018455A JP2015018455A JP6293071B2 JP 6293071 B2 JP6293071 B2 JP 6293071B2 JP 2015018455 A JP2015018455 A JP 2015018455A JP 2015018455 A JP2015018455 A JP 2015018455A JP 6293071 B2 JP6293071 B2 JP 6293071B2
- Authority
- JP
- Japan
- Prior art keywords
- puncture
- carrier
- plug
- plug device
- hydrogel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/06—Coatings containing a mixture of two or more compounds
Description
患者の脈管構造に経皮的にアクセスするための、例えば脈管内で作業を行うため、および作業完了後に生じる穿刺を閉塞するための器具および方法が知られている。例えば、中空針を患者の皮膚およびその被覆組織を通して血管内に挿入することができる。ガイドワイヤを針管腔から血管内に通すことができ、その後針を取り除くこともできる。次に誘導シースをガイドワイヤ上に沿って進め、例えば一緒に、もしくは続けて一つまたは複数の拡張器を血管内に通すこともできる。医療処置を行うために、カテーテルまたはその他装置を誘導シースの中およびガイドワイヤの上をある位置まで進めることもできる。このように誘導シースは、脈管装置の血管内へのアクセスおよび/または導入を容易にすると同時に、血管壁の外傷を最小限にし、かつ/または失血を最小限にする。処置終了後に装置および誘導シースは除去され、皮膚と血管壁の間に伸びる穿刺が残ることがある。
発明は、体内の穿刺を閉塞するための器具、より具体的には血管に伸びる脈管穿刺内に一時的もしくは永久的な止血を提供するための器具、および/または患者の皮膚から血管もしくはその他体部管腔に伸びる経皮的穿刺の中に閉塞栓を送達するための器具を目的とする。
図面に転ずると、図1A〜1Dは組織(図示せず)を貫通して伸びる穿刺を閉塞するための装置2を描いている。一般的には、装置2はその上に第一ヒドロゲル前駆体6および第二ヒドロゲル前駆体7を配した、例えば栓の形をした担体またはコア4を具備する。第一および第二ヒドロゲル前駆体6、7は、担体4の上に非反応状態で配される。第一および第二ヒドロゲル前駆体6、7は、例えば水性の生理的環境に曝される前もしくは曝されるまでは非反応状態を保つことができる。水性の生理的環境は、例えば組織を貫通して伸びる穿刺跡の内側に存在するだろう。
Claims (10)
- 組織路の端部に配置された血管壁の貫通部を閉塞する装置であって、
近位端及び遠位端を有するシャフトと、
前記シャフトの遠位端付近の閉鎖要素であって、前記組織路を通って通過するために径方向に収縮した構造と血管内に展開して前記貫通部を閉鎖するために径方向に拡張した構造との間で変形可能な閉鎖要素と、
前記閉鎖要素に近接して前記シャフトの外面に配置された止血インプラントと、
前記止血インプラントを覆うように配置されて近位方向に引き戻し可能な保護スリーブと
を含み、
前記止血インプラントは、前記シャフトの外面と前記保護スリーブの内面との間に配置される装置。 - 前記閉鎖要素は拡張式ワイヤメッシュを含む請求項1に記載の装置。
- 前記閉鎖要素は拡張式フレームを含む請求項1に記載の装置。
- 前記閉鎖要素は膨張式バルーンを含む請求項1に記載の装置。
- 前記径方向に収縮した構造と前記径方向に拡張した構造との間で前記拡張式ワイヤメッシュを作動させるためのアクチュエータをさらに含む請求項2に記載の装置。
- 前記止血インプラントは前記シャフトに担持された円筒形プラグを含む請求項1に記載の装置。
- 前記止血インプラントはコラーゲンを含む請求項1に記載の装置。
- 前記止血インプラントはコラーゲンを含む請求項5に記載の装置。
- 前記止血インプラントはポリエチレングリコールを含む請求項1に記載の装置。
- 前記シャフトは管状体を含む請求項1に記載の装置。
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US10/982,387 | 2004-11-05 | ||
US10/982,384 | 2004-11-05 | ||
US10/982,384 US7335220B2 (en) | 2004-11-05 | 2004-11-05 | Apparatus and methods for sealing a vascular puncture |
US10/982,387 US7790192B2 (en) | 1998-08-14 | 2004-11-05 | Apparatus and methods for sealing a vascular puncture |
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JP2017245417A Division JP7082873B2 (ja) | 2004-11-05 | 2017-12-21 | 穿刺部を閉塞する器具 |
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JP2012237135A Expired - Fee Related JP5777110B2 (ja) | 2004-11-05 | 2012-10-26 | 脈管穿刺を閉塞するための器具 |
JP2015018455A Active JP6293071B2 (ja) | 2004-11-05 | 2015-02-02 | 脈管穿刺を閉塞するための器具 |
JP2015148223A Active JP6491562B2 (ja) | 2004-11-05 | 2015-07-28 | 血管の壁の貫通部又は穿刺部を封止する器具 |
JP2017100990A Active JP6186536B1 (ja) | 2004-11-05 | 2017-05-22 | 血管の壁の貫通部を封止する器具 |
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JP2012237135A Expired - Fee Related JP5777110B2 (ja) | 2004-11-05 | 2012-10-26 | 脈管穿刺を閉塞するための器具 |
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JP2017100990A Active JP6186536B1 (ja) | 2004-11-05 | 2017-05-22 | 血管の壁の貫通部を封止する器具 |
JP2017245417A Active JP7082873B2 (ja) | 2004-11-05 | 2017-12-21 | 穿刺部を閉塞する器具 |
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US (11) | US7790192B2 (ja) |
EP (4) | EP2845613B1 (ja) |
JP (6) | JP5243036B2 (ja) |
CA (1) | CA2583235C (ja) |
WO (1) | WO2006052611A1 (ja) |
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