JP6268100B2 - 鼻腔内デクスメデトミジン組成物およびその使用方法 - Google Patents

鼻腔内デクスメデトミジン組成物およびその使用方法 Download PDF

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JP6268100B2
JP6268100B2 JP2014546186A JP2014546186A JP6268100B2 JP 6268100 B2 JP6268100 B2 JP 6268100B2 JP 2014546186 A JP2014546186 A JP 2014546186A JP 2014546186 A JP2014546186 A JP 2014546186A JP 6268100 B2 JP6268100 B2 JP 6268100B2
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dexmedetomidine
minutes
hours
pharmaceutically acceptable
administered
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JP2015513309A (ja
JP2015513309A5 (enExample
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ジェラルディン・エイ・ヘンウッド
ランドール・ジェイ・マック
ジョン・ジョゼフ・コレング・ジュニア
クリストファー・ティ・シャー
チャールズ・アレクサンダー・フレイヤー
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レクロ・ファーマ,インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2014546186A 2011-12-11 2012-12-11 鼻腔内デクスメデトミジン組成物およびその使用方法 Expired - Fee Related JP6268100B2 (ja)

Applications Claiming Priority (3)

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US201161569255P 2011-12-11 2011-12-11
US61/569,255 2011-12-11
PCT/US2012/068988 WO2013090278A2 (en) 2011-12-11 2012-12-11 Intranasal dexmedetomidine compositions and methods of use thereof

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JP2017172633A Division JP6505177B2 (ja) 2011-12-11 2017-09-08 鼻腔内デクスメデトミジン組成物およびその使用方法

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JP2015513309A JP2015513309A (ja) 2015-05-07
JP2015513309A5 JP2015513309A5 (enExample) 2016-01-21
JP6268100B2 true JP6268100B2 (ja) 2018-01-24

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US (2) US9795559B2 (enExample)
EP (2) EP2787970B1 (enExample)
JP (2) JP6268100B2 (enExample)
KR (1) KR102190009B1 (enExample)
CN (1) CN104470516A (enExample)
AU (2) AU2012352528B9 (enExample)
BR (1) BR112014019171A8 (enExample)
CA (1) CA2858721C (enExample)
CL (1) CL2014001515A1 (enExample)
CO (1) CO7000773A2 (enExample)
CR (1) CR20140318A (enExample)
DO (1) DOP2014000123A (enExample)
EC (1) ECSP14007644A (enExample)
IL (1) IL232977B (enExample)
MX (1) MX367286B (enExample)
PE (1) PE20142314A1 (enExample)
PH (1) PH12014501273A1 (enExample)
RU (1) RU2692245C2 (enExample)
SG (2) SG11201403094TA (enExample)
WO (1) WO2013090278A2 (enExample)

Cited By (1)

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JP2018030850A (ja) * 2011-12-11 2018-03-01 レクロ・ファーマ,インコーポレーテッド 鼻腔内デクスメデトミジン組成物およびその使用方法

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Cited By (2)

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Publication number Priority date Publication date Assignee Title
JP2018030850A (ja) * 2011-12-11 2018-03-01 レクロ・ファーマ,インコーポレーテッド 鼻腔内デクスメデトミジン組成物およびその使用方法
US10682311B2 (en) 2011-12-11 2020-06-16 Baudax Bio, Inc. Intranasal dexmedetomidine compositions and methods of use thereof

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IL232977A0 (en) 2014-07-31
US20180055764A1 (en) 2018-03-01
CN104470516A (zh) 2015-03-25
CL2014001515A1 (es) 2014-12-05
CA2858721C (en) 2021-03-16
WO2013090278A3 (en) 2014-12-24
ECSP14007644A (es) 2015-11-30
NZ626999A (en) 2016-07-29
EP2787970A2 (en) 2014-10-15
PE20142314A1 (es) 2015-01-23
JP2015513309A (ja) 2015-05-07
BR112014019171A8 (pt) 2017-07-11
AU2018200591A1 (en) 2018-02-15
RU2692245C2 (ru) 2019-06-24
SG11201403094TA (en) 2014-10-30
EP3406247A1 (en) 2018-11-28
JP6505177B2 (ja) 2019-04-24
US9795559B2 (en) 2017-10-24
KR20140107329A (ko) 2014-09-04
HK1203049A1 (en) 2015-10-16
WO2013090278A2 (en) 2013-06-20
AU2012352528B2 (en) 2017-10-26
DOP2014000123A (es) 2014-12-31
EP2787970A4 (en) 2015-10-28
AU2012352528A1 (en) 2014-07-10
IL232977B (en) 2019-01-31
SG10201604653TA (en) 2016-07-28
US10682311B2 (en) 2020-06-16
US20130178465A1 (en) 2013-07-11
CA2858721A1 (en) 2013-06-20
AU2018200591B2 (en) 2018-11-29
CR20140318A (es) 2014-10-28
BR112014019171A2 (enExample) 2017-06-20
MX367286B (es) 2019-08-13
AU2012352528B9 (en) 2017-11-02
MX2014006961A (es) 2014-09-22
RU2014128343A (ru) 2016-01-27
EP2787970B1 (en) 2018-04-11
KR102190009B1 (ko) 2020-12-15
PH12014501273A1 (en) 2014-09-08
JP2018030850A (ja) 2018-03-01
CO7000773A2 (es) 2014-07-21

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