JP6241932B2 - 腫瘍性疾患のための治療 - Google Patents

腫瘍性疾患のための治療 Download PDF

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Publication number
JP6241932B2
JP6241932B2 JP2013526085A JP2013526085A JP6241932B2 JP 6241932 B2 JP6241932 B2 JP 6241932B2 JP 2013526085 A JP2013526085 A JP 2013526085A JP 2013526085 A JP2013526085 A JP 2013526085A JP 6241932 B2 JP6241932 B2 JP 6241932B2
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cancer
disease
treatment
neoplastic disease
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Japanese (ja)
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JP2013536236A (ja
JP2013536236A5 (enExample
Inventor
シマール，ジョン
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Xbiotech Inc
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Xbiotech Inc
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Publication of JP2013536236A publication Critical patent/JP2013536236A/ja
Publication of JP2013536236A5 publication Critical patent/JP2013536236A5/ja
Priority to JP2016100753A priority Critical patent/JP6917681B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2013526085A 2010-08-23 2011-08-23 腫瘍性疾患のための治療 Active JP6241932B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2016100753A JP6917681B2 (ja) 2010-08-23 2016-05-19 腫瘍性疾患のための治療

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US37609710P 2010-08-23 2010-08-23
US61/376,097 2010-08-23
US40675910P 2010-10-26 2010-10-26
US61/406,759 2010-10-26
US41118310P 2010-11-08 2010-11-08
US61/411,183 2010-11-08
US201161480635P 2011-04-29 2011-04-29
US61/480,635 2011-04-29
PCT/US2011/048747 WO2012027324A2 (en) 2010-08-23 2011-08-23 Treatment for neoplastic diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016100753A Division JP6917681B2 (ja) 2010-08-23 2016-05-19 腫瘍性疾患のための治療

Publications (3)

Publication Number Publication Date
JP2013536236A JP2013536236A (ja) 2013-09-19
JP2013536236A5 JP2013536236A5 (enExample) 2015-04-30
JP6241932B2 true JP6241932B2 (ja) 2017-12-06

Family

ID=45594256

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2013526085A Active JP6241932B2 (ja) 2010-08-23 2011-08-23 腫瘍性疾患のための治療
JP2016100753A Active JP6917681B2 (ja) 2010-08-23 2016-05-19 腫瘍性疾患のための治療
JP2019125907A Active JP7316120B2 (ja) 2010-08-23 2019-07-05 腫瘍性疾患のための治療
JP2021096528A Pending JP2021138750A (ja) 2010-08-23 2021-06-09 腫瘍性疾患のための治療
JP2025133305A Pending JP2025166117A (ja) 2010-08-23 2025-08-08 腫瘍性疾患のための治療

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2016100753A Active JP6917681B2 (ja) 2010-08-23 2016-05-19 腫瘍性疾患のための治療
JP2019125907A Active JP7316120B2 (ja) 2010-08-23 2019-07-05 腫瘍性疾患のための治療
JP2021096528A Pending JP2021138750A (ja) 2010-08-23 2021-06-09 腫瘍性疾患のための治療
JP2025133305A Pending JP2025166117A (ja) 2010-08-23 2025-08-08 腫瘍性疾患のための治療

Country Status (17)

Country Link
US (3) US10294296B2 (enExample)
EP (3) EP3075394B1 (enExample)
JP (5) JP6241932B2 (enExample)
KR (7) KR20210128021A (enExample)
CN (3) CN103153340A (enExample)
AU (1) AU2011293554B9 (enExample)
DK (1) DK2608808T3 (enExample)
ES (2) ES2856723T3 (enExample)
IL (2) IL262856B (enExample)
MX (2) MX342776B (enExample)
NZ (1) NZ607472A (enExample)
PH (2) PH12013500316A1 (enExample)
PT (1) PT2608808T (enExample)
RU (2) RU2013110030A (enExample)
SG (1) SG187853A1 (enExample)
WO (1) WO2012027324A2 (enExample)
ZA (1) ZA201301420B (enExample)

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US10975146B2 (en) 2018-06-29 2021-04-13 Cedars-Sinai Medical Center Interleukin-1 inhibition for combination treatment of pancreatic cancer
CA3095675A1 (en) 2020-10-07 2022-04-07 Xbiotech Inc. True human antibody specific for interleukin 1 alpha (il-1a)
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Also Published As

Publication number Publication date
WO2012027324A2 (en) 2012-03-01
IL262856A (en) 2018-12-31
PH12016500578B1 (en) 2017-03-06
KR20240134401A (ko) 2024-09-09
MX342776B (es) 2016-10-12
KR20210128021A (ko) 2021-10-25
ES2856723T3 (es) 2021-09-28
KR20200010609A (ko) 2020-01-30
CN107281488A (zh) 2017-10-24
KR20160062200A (ko) 2016-06-01
ES2622482T3 (es) 2017-07-06
KR20130108305A (ko) 2013-10-02
KR20170113687A (ko) 2017-10-12
PH12013500316A1 (en) 2016-09-02
EP3075394B1 (en) 2018-11-28
AU2011293554B9 (en) 2015-03-19
NZ607472A (en) 2014-09-26
JP2013536236A (ja) 2013-09-19
MX2013002160A (es) 2013-04-05
RU2679119C2 (ru) 2019-02-06
EP3443985A1 (en) 2019-02-20
EP2608808B1 (en) 2017-01-18
JP7316120B2 (ja) 2023-07-27
PH12016500578A1 (en) 2017-03-06
CN103153340A (zh) 2013-06-12
JP2016175939A (ja) 2016-10-06
KR20180116458A (ko) 2018-10-24
JP2019194233A (ja) 2019-11-07
RU2017112088A (ru) 2019-01-24
EP3075394A1 (en) 2016-10-05
JP2025166117A (ja) 2025-11-05
WO2012027324A3 (en) 2012-05-10
CN107252484A (zh) 2017-10-17
IL262856B (en) 2020-06-30
EP2608808A4 (en) 2014-01-15
US11932688B2 (en) 2024-03-19
JP2021138750A (ja) 2021-09-16
ZA201301420B (en) 2014-04-30
EP3443985B1 (en) 2020-12-16
EP2608808A2 (en) 2013-07-03
US10294296B2 (en) 2019-05-21
JP6917681B2 (ja) 2021-08-11
US20230382989A1 (en) 2023-11-30
AU2011293554B2 (en) 2015-02-26
PT2608808T (pt) 2017-04-24
CN107281488B (zh) 2021-02-09
RU2013110030A (ru) 2014-09-27
KR101910760B1 (ko) 2018-10-22
IL275350A (en) 2020-07-30
RU2017112088A3 (enExample) 2019-01-24
IL275350B (en) 2021-07-29
MX388939B (es) 2025-03-20
KR102104296B1 (ko) 2020-04-27
SG187853A1 (en) 2013-03-28
KR102748255B1 (ko) 2024-12-31
US20120045444A1 (en) 2012-02-23
AU2011293554A1 (en) 2013-03-07
US20190127460A1 (en) 2019-05-02
KR102314003B1 (ko) 2021-10-19
DK2608808T3 (en) 2017-04-24

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