JP6182593B2 - 置換ヘテロ二環化合物、組成物及び医薬並びにそれらの用途 - Google Patents

置換ヘテロ二環化合物、組成物及び医薬並びにそれらの用途 Download PDF

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JP6182593B2
JP6182593B2 JP2015506355A JP2015506355A JP6182593B2 JP 6182593 B2 JP6182593 B2 JP 6182593B2 JP 2015506355 A JP2015506355 A JP 2015506355A JP 2015506355 A JP2015506355 A JP 2015506355A JP 6182593 B2 JP6182593 B2 JP 6182593B2
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phenyl
dihydro
pyrrolo
methyl
benzoxazepin
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JP2015514749A (ja
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タッカー，マヘシュ
コウル，サモン
ブーニヤ，デブナット
ムークティア，カシム
クーハデ，サントッシュ
ムノット，ヨゲシュ
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アドヴィーナス セラピューティクス リミテッド
アドヴィーナス セラピューティクス リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D487/04—Ortho-condensed systems

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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2015506355A 2012-04-20 2013-04-18 置換ヘテロ二環化合物、組成物及び医薬並びにそれらの用途 Active JP6182593B2 (ja)

Applications Claiming Priority (3)

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IN1573/CHE/2012 2012-04-20
IN1573CH2012 IN2012CH01573A (enExample) 2012-04-20 2013-04-18
PCT/IN2013/000259 WO2013157022A1 (en) 2012-04-20 2013-04-18 Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof

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JP6182593B2 true JP6182593B2 (ja) 2017-08-16

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US (1) US9233983B2 (enExample)
EP (1) EP2838898B1 (enExample)
JP (1) JP6182593B2 (enExample)
CN (1) CN104662018B (enExample)
AU (1) AU2013250726B2 (enExample)
CA (1) CA2869954C (enExample)
IL (1) IL235146A (enExample)
IN (1) IN2012CH01573A (enExample)
WO (1) WO2013157022A1 (enExample)
ZA (1) ZA201407341B (enExample)

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